5GUT
The crystal structure of mouse DNMT1 (731-1602) mutant - N1248A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA (cytosine-5)-methyltransferase 1 | polymer | 872 | 98850.5 | 1 | UniProt (P13864) Pfam (PF01426) Pfam (PF00145) | Mus musculus (Mouse) | Met-1,DNA methyltransferase MmuI,M.MmuI,MCMT |
| 2 | B (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) PubChem (16760024) PubChem (193) PubChem (25210495) PubChem (13792) PubChem (177678424) PubChem (44361184) PubChem (21125603) PubChem (46936206) PubChem (50989525) PubChem (25203782) PubChem (51380914) PubChem (52224398) PubChem (189149) PubChem (57544532) PubChem (439155) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (52224400) PubChem (5284331) PubChem (6419189) PubChem (118374891) PubChem (118560068) PubChem (71170554) PubChem (13231890) PubChem (164157219) PubChem (126969526) PubChem (129105892) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525) | |||
| 3 | C, D (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E, F, G, H, I... (A) | SULFATE ION | non-polymer | 96.1 | 10 | Chemie (SO4) | |||
| 5 | O (A) | water | water | 18.0 | 479 | Chemie (HOH) |
Sequence modifications
A: 731 - 1602 (UniProt: P13864)
| PDB | External Database | Details |
|---|---|---|
| Ala 1248 | Asn 1248 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 98850.5 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1475.9 | |
| All* | Total formula weight | 100326.3 |
