5GUT
The crystal structure of mouse DNMT1 (731-1602) mutant - N1248A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA (cytosine-5)-methyltransferase 1 | polymer | 872 | 98850.5 | 1 | UniProt (P13864) Pfam (PF01426) Pfam (PF00145) | Mus musculus (Mouse) | Met-1,DNA methyltransferase MmuI,M.MmuI,MCMT |
| 2 | B (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 3 | C, D (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E, F, G, H, I... (A) | SULFATE ION | non-polymer | 96.1 | 10 | Chemie (SO4) | |||
| 5 | O (A) | water | water | 18.0 | 479 | Chemie (HOH) |
Sequence modifications
A: 731 - 1602 (UniProt: P13864)
| PDB | External Database | Details |
|---|---|---|
| Ala 1248 | Asn 1248 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 98850.5 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1475.9 | |
| All* | Total formula weight | 100326.3 |
