6KX2

Crystal structure of GDP bound RhoA protein

Summary for 6KX2

• Entry DOI: 10.2210/pdb6kx2/pdb
• Descriptor: Transforming protein RhoA, GUANOSINE-5'-DIPHOSPHATE (3 entities in total)
• Functional Keywords: rhoa, gdp, complex, cell invasion
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 20884.53

Authors

Zhang, H.,Luo, C. (deposition date: 2019-09-09, release date: 2020-08-19, Last modification date: 2023-11-22)

• Primary citation: Sun, Z.,Zhang, H.,Zhang, Y.,Liao, L.,Zhou, W.,Zhang, F.,Lian, F.,Huang, J.,Xu, P.,Zhang, R.,Lu, W.,Zhu, M.,Tao, H.,Yang, F.,Ding, H.,Chen, S.,Yue, L.,Zhou, B.,Zhang, N.,Tan, M.,Jiang, H.,Chen, K.,Liu, B.,Liu, C.,Dang, Y.,Luo, C.; Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion.; Adv Sci, 7:2000098-2000098, 2020; PubMed: 32714746; DOI: 10.1002/advs.202000098

Experimental method

X-RAY DIFFRACTION (1.454 Å)