3NSP

Crystal structure of tetrameric RXRalpha-LBD

Summary for 3NSP

Related3NSQ
DescriptorRetinoid X receptor, alpha (2 entities in total)
Functional Keywordsnuclear receptor retinoic x recepor alpha ligand binding domain, transcription
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total molecular weight53712.08
Authors
Zhang, H.,Hu, T.,Li, L.,Zhou, R.,Chen, L.,Hu, L.,Jiang, H.,Shen, X. (deposition date: 2010-07-02, release date: 2010-11-17, Last modification date: 2012-04-11)
Primary citation
Zhang, H.,Zhou, R.,Li, L.,Chen, J.,Chen, L.,Li, C.,Ding, H.,Yu, L.,Hu, L.,Jiang, H.,Shen, X.
Danthron functions as a retinoic X receptor antagonist by stabilizing tetramers of the receptor.
J.Biol.Chem., 286:1868-1875, 2011
PubMed: 21084305 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M110.166215
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.9 Å)
NMR Information
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.29917014.5%1.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3nsp
no rotation
Molmil generated image of 3nsp
rotated about x axis by 90°
Molmil generated image of 3nsp
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 3nsp
no rotation
Molmil generated image of 3nsp
rotated about x axis by 90°
Molmil generated image of 3nsp
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (3nsp.pdb1.gz [121.86 KB])