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9C9R
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BU of 9c9r by Molmil
Crystal structure of Chaetomium thermophilum Gcn2 HisRS-like domain, F1090C/G1326S variant
Descriptor: non-specific serine/threonine protein kinase
Authors:Bou-Nader, C, Bahmanjah, S, Zhang, J.
Deposit date:2024-06-14
Release date:2024-08-21
Last modified:2024-09-18
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Gcn2 structurally mimics and functionally repurposes the HisRS enzyme for the integrated stress response.
Proc.Natl.Acad.Sci.USA, 121, 2024
9C9Q
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BU of 9c9q by Molmil
Crystal structure of Chaetomium thermophilum Gcn2 HisRS-like domain
Descriptor: non-specific serine/threonine protein kinase
Authors:Bou-Nader, C, Bahmanjah, S, Zhang, J.
Deposit date:2024-06-14
Release date:2024-08-21
Last modified:2024-09-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Gcn2 structurally mimics and functionally repurposes the HisRS enzyme for the integrated stress response.
Proc.Natl.Acad.Sci.USA, 121, 2024
2X7L
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BU of 2x7l by Molmil
Implications of the HIV-1 Rev dimer structure at 3.2A resolution for multimeric binding to the Rev response element
Descriptor: FAB HEAVY CHAIN, FAB LIGHT CHAIN, PROTEIN REV
Authors:DiMattia, M.A, Watts, N.R, Stahl, S.J, Rader, C, Wingfield, P.T, Stuart, D.I, Steven, A.C, Grimes, J.M.
Deposit date:2010-03-01
Release date:2010-03-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Implications of the HIV-1 Rev Dimer Structure at 3. 2 A Resolution for Multimeric Binding to the Rev Response Element.
Proc.Natl.Acad.Sci.USA, 107, 2010
7TUS
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BU of 7tus by Molmil
Sculpting a uniquely reactive cysteine residue for site-specific antibody conjugation
Descriptor: Antibody Heavy Chain, Antibody Light Chain, DI(HYDROXYETHYL)ETHER, ...
Authors:Park, H, Rader, C.
Deposit date:2022-02-03
Release date:2022-06-08
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Sculpting a Uniquely Reactive Cysteine Residue for Site-Specific Antibody Conjugation.
Bioconjug.Chem., 33, 2022
2PYP
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BU of 2pyp by Molmil
PHOTOACTIVE YELLOW PROTEIN, PHOTOSTATIONARY STATE, 50% GROUND STATE, 50% BLEACHED
Descriptor: 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN
Authors:Genick, U.K, Borgstahl, G.E.O, Ng, K, Ren, Z, Pradervand, C, Burke, P, Srajer, V, Teng, T, Schildkamp, W, Mcree, D.E, Moffat, K, Getzoff, E.D.
Deposit date:1997-02-03
Release date:1998-04-29
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a protein photocycle intermediate by millisecond time-resolved crystallography.
Science, 275, 1997
2PYR
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BU of 2pyr by Molmil
PHOTOACTIVE YELLOW PROTEIN, 1 NANOSECOND INTERMEDIATE (287K)
Descriptor: 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN
Authors:Perman, B, Srajer, V, Ren, Z, Teng, T.Y, Pradervand, C, Ursby, T, Bourgeois, D, Schotte, F, Wulff, M, Kort, R, Hellingwerf, K, Moffat, K.
Deposit date:1998-03-04
Release date:1999-04-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Energy transduction on the nanosecond time scale: early structural events in a xanthopsin photocycle.
Science, 279, 1998
6DZR
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BU of 6dzr by Molmil
Crystal structure of h38C2 K99R mutation
Descriptor: CITRATE ANION, SULFATE ION, h38c2 heavy chain, ...
Authors:Park, H, Rader, C.
Deposit date:2018-07-05
Release date:2019-07-10
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Site-Selective Antibody Functionalization via Orthogonally Reactive Arginine and Lysine Residues.
Cell Chem Biol, 26, 2019
2LNY
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BU of 2lny by Molmil
ShB peptide structure bound to negatively charged lipid-bilayer after Molecular Dynamics refinement
Descriptor: ShB peptide
Authors:Weingarth, M.
Deposit date:2012-01-06
Release date:2012-08-08
Last modified:2024-05-15
Method:SOLID-STATE NMR
Cite:Supramolecular structure of membrane-associated polypeptides by combining solid-state NMR and molecular dynamics simulations.
Biophys.J., 103, 2012
6F7T
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BU of 6f7t by Molmil
Crystal Structure of an Fab fragment in complex with a peptide from Bacillus subtilis RNase Y
Descriptor: FAB RY79-90, HEAVY CHAIN, LIGHT CHAIN, ...
Authors:Golinelli-Pimpaneau, B, Hardouin, P.
Deposit date:2017-12-11
Release date:2018-10-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Dissociation of the Dimer of the Intrinsically Disordered Domain of RNase Y upon Antibody Binding.
Biophys. J., 115, 2018
8CIY
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BU of 8ciy by Molmil
DNA-polymerase sliding clamp (DnaN) from Escherichia coli in complex with Cyclohexyl-Griselimycin.
Descriptor: ACETATE ION, Beta sliding clamp, CALCIUM ION, ...
Authors:Fu, C, Liu, Y, Walt, C, Bader, C, Rasheed, S, Lukat, P, Neuber, M, Blankenfeldt, W, Kalinina, O, Mueller, R.
Deposit date:2023-02-11
Release date:2023-11-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Elucidation of unusual biosynthesis and DnaN-targeting mode of action of potent anti-tuberculosis antibiotics Mycoplanecins.
Nat Commun, 15, 2024
8CIZ
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BU of 8ciz by Molmil
DNA-polymerase sliding clamp (DnaN) from Escherichia coli in complex with Mycoplanecin A.
Descriptor: Beta sliding clamp, Mycoplanecin A
Authors:Fu, C, Liu, Y, Walt, C, Bader, C, Rasheed, S, Lukat, P, Neuber, M, Blankenfeldt, W, Kalinina, O, Mueller, R.
Deposit date:2023-02-11
Release date:2023-11-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Elucidation of unusual biosynthesis and DnaN-targeting mode of action of potent anti-tuberculosis antibiotics Mycoplanecins.
Nat Commun, 15, 2024
8CIX
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BU of 8cix by Molmil
DNA-polymerase sliding clamp (DnaN) from Escherichia coli in complex with Griselimycin.
Descriptor: ACETATE ION, Beta sliding clamp, CALCIUM ION, ...
Authors:Fu, C, Liu, Y, Walt, C, Bader, C, Rasheed, S, Lukat, P, Neuber, M, Blankenfeldt, W, Kalinina, O, Mueller, R.
Deposit date:2023-02-11
Release date:2023-11-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Elucidation of unusual biosynthesis and DnaN-targeting mode of action of potent anti-tuberculosis antibiotics Mycoplanecins.
Nat Commun, 15, 2024
7BET
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BU of 7bet by Molmil
Structure of Ribonucleotide reductase R2 from Escherichia coli collected by femtosecond serial crystallography on a COC membrane
Descriptor: FE (III) ION, Ribonucleoside-diphosphate reductase 1 subunit beta
Authors:Aurelius, O, John, J, Martiel, I, Marsh, M, Vera, L, Huang, C.Y, Olieric, V, Leonarski, P, Nass, K, Padeste, C, Karpik, A, Hogbom, M, Wang, M, Pedrini, B.
Deposit date:2020-12-24
Release date:2022-01-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Commissioning results from the SwissMX instrument for fixed target macromolecular crystallography at SwissFEL
To Be Published
9CBS
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BU of 9cbs by Molmil
Crystal structure of Chaetomium thermophilum Gcn2 HisRS-like domain, catalytic domain
Descriptor: non-specific serine/threonine protein kinase
Authors:Zhang, J.
Deposit date:2024-06-20
Release date:2024-08-21
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Gcn2 structurally mimics and functionally repurposes the HisRS enzyme for the integrated stress response.
Proc.Natl.Acad.Sci.USA, 121, 2024
7AT6
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BU of 7at6 by Molmil
Structure of thaumatin collected by femtosecond serial crystallography on a COC membrane
Descriptor: L(+)-TARTARIC ACID, R-1,2-PROPANEDIOL, SODIUM ION, ...
Authors:Martiel, I, Marsh, M, Vera, L, Huang, C.Y, Olieric, V, Leonarski, P, Nass, K, Padeste, C, Karpik, A, Wang, M, Pedrini, B.
Deposit date:2020-10-29
Release date:2021-11-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Commissioning results from the SwissMX instrument for fixed target macromolecular crystallography at SwissFEL
To Be Published
6CLW
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BU of 6clw by Molmil
Crystal structure of TnmH
Descriptor: O-methyltransferase
Authors:Chang, C.Y, Annaval, T, Adhikari, A, Yan, X, Shen, B.
Deposit date:2018-03-02
Release date:2019-03-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Characterization of TnmH as anO-Methyltransferase Revealing Insights into Tiancimycin Biosynthesis and Enabling a Biocatalytic Strategy To Prepare Antibody-Tiancimycin Conjugates.
J.Med.Chem., 63, 2020
6CLX
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BU of 6clx by Molmil
Crystal structure of TnmH in complex with SAM
Descriptor: O-methyltransferase, S-ADENOSYLMETHIONINE
Authors:Chang, C.Y, Annaval, T, Adhikari, A, Yan, X, Shen, B.
Deposit date:2018-03-02
Release date:2019-03-06
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Characterization of TnmH as anO-Methyltransferase Revealing Insights into Tiancimycin Biosynthesis and Enabling a Biocatalytic Strategy To Prepare Antibody-Tiancimycin Conjugates.
J.Med.Chem., 63, 2020
8V1I
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BU of 8v1i by Molmil
Crystal structure of human mascRNA
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
Authors:Skeparnias, I, Zhang, J.
Deposit date:2023-11-20
Release date:2024-07-10
Last modified:2024-07-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of MALAT1 RNA maturation and mascRNA biogenesis.
Nat.Struct.Mol.Biol., 2024
8V1H
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BU of 8v1h by Molmil
Crystal structure of human pre-mascRNA
Descriptor: SODIUM ION, pre-mascRNA
Authors:Skeparnias, I, Zhang, J.
Deposit date:2023-11-20
Release date:2024-07-10
Last modified:2024-07-17
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Structural basis of MALAT1 RNA maturation and mascRNA biogenesis.
Nat.Struct.Mol.Biol., 2024
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