8CIZ
DNA-polymerase sliding clamp (DnaN) from Escherichia coli in complex with Mycoplanecin A.
Summary for 8CIZ
Entry DOI | 10.2210/pdb8ciz/pdb |
Related PRD ID | PRD_002467 |
Descriptor | Beta sliding clamp, Mycoplanecin A (3 entities in total) |
Functional Keywords | dnan, sliding clamp, dna-polymerase beta subunit, antibiotic, natural product, anti-tuberculosis, transferase |
Biological source | Escherichia coli More |
Total number of polymer chains | 4 |
Total formula weight | 84206.68 |
Authors | Fu, C.,Liu, Y.,Walt, C.,Bader, C.,Rasheed, S.,Lukat, P.,Neuber, M.,Blankenfeldt, W.,Kalinina, O.,Mueller, R. (deposition date: 2023-02-11, release date: 2023-11-29, Last modification date: 2024-02-07) |
Primary citation | Fu, C.,Liu, Y.,Walt, C.,Rasheed, S.,Bader, C.D.,Lukat, P.,Neuber, M.,Haeckl, F.P.J.,Blankenfeldt, W.,Kalinina, O.V.,Muller, R. Elucidation of unusual biosynthesis and DnaN-targeting mode of action of potent anti-tuberculosis antibiotics Mycoplanecins. Nat Commun, 15:791-791, 2024 Cited by PubMed: 38278788DOI: 10.1038/s41467-024-44953-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.27 Å) |
Structure validation
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