2X7L

Implications of the HIV-1 Rev dimer structure at 3.2A resolution for multimeric binding to the Rev response element

Summary for 2X7L

DescriptorFAB HEAVY CHAIN, FAB LIGHT CHAIN, PROTEIN REV (3 entities in total)
Functional Keywordsnuclear export, immune system, post-transcriptional regulation
Biological sourcesynthetic construct
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Total number of polymer chains18
Total molecular weight365002.76
Authors
DiMattia, M.A.,Watts, N.R.,Stahl, S.J.,Rader, C.,Wingfield, P.T.,Stuart, D.I.,Steven, A.C.,Grimes, J.M. (deposition date: 2010-03-01, release date: 2010-03-23, Last modification date: 2019-02-20)
Primary citation
Dimattia, M.A.,Watts, N.R.,Stahl, S.J.,Rader, C.,Wingfield, P.T.,Stuart, D.I.,Steven, A.C.,Grimes, J.M.
Implications of the HIV-1 Rev Dimer Structure at 3. 2 A Resolution for Multimeric Binding to the Rev Response Element.
Proc.Natl.Acad.Sci.USA, 107:5810-, 2010
PubMed: 20231488 (PDB entries with the same primary citation)
DOI: 10.1073/PNAS.0914946107
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.17 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.26510 3.9% 16.0% 2.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2x7l
no rotation
Molmil generated image of 2x7l
rotated about x axis by 90°
Molmil generated image of 2x7l
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 2x7l
no rotation
Molmil generated image of 2x7l
rotated about x axis by 90°
Molmil generated image of 2x7l
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (2x7l.pdb1.gz [172.01 KB])
Coordinate files for Biological unit (2x7l.pdb4.gz [171.33 KB])
Coordinate files for Biological unit (2x7l.pdb3.gz [173.02 KB])
Coordinate files for Biological unit (2x7l.pdb2.gz [172.85 KB])
Coordinate files for Biological unit (2x7l.pdb6.gz [171.34 KB])
Coordinate files for Biological unit (2x7l.pdb5.gz [170.94 KB])
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