6U85
Site-specific lysine arylation as an alternative bioconjugation strategy for chemically programmed antibodies and antibody-drug conjugates
Summary for 6U85
Entry DOI | 10.2210/pdb6u85/pdb |
Descriptor | Antibody Fab heavy chain, antibody Fab Light chain, GLYCEROL, ... (4 entities in total) |
Functional Keywords | single chain fv, scfv, antibody, ror2, kringle domain, receptor tyrosine kinase-like orphan receptor, phage display, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 48077.60 |
Authors | |
Primary citation | Hwang, D.,Tsuji, K.,Park, H.,Burke Jr., T.R.,Rader, C. Site-Specific Lysine Arylation as an Alternative Bioconjugation Strategy for Chemically Programmed Antibodies and Antibody-Drug Conjugates. Bioconjug.Chem., 30:2889-2896, 2019 Cited by PubMed: 31675216DOI: 10.1021/acs.bioconjchem.9b00609 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.78 Å) |
Structure validation
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