9CBS

Crystal structure of Chaetomium thermophilum Gcn2 HisRS-like domain, catalytic domain

Summary for 9CBS

Entry DOI	10.2210/pdb9cbs/pdb
Related	9C9Q 9C9R
Descriptor	non-specific serine/threonine protein kinase (2 entities in total)
Functional Keywords	stress response, gcn2, trna-binding, regulatory, translation
Biological source	Thermochaetoides thermophila
Total number of polymer chains	4
Total formula weight	150431.83
Authors	Zhang, J. (deposition date: 2024-06-20, release date: 2024-08-21, Last modification date: 2024-09-18)
Primary citation	Bou-Nader, C.,Gaikwad, S.,Bahmanjah, S.,Zhang, F.,Hinnebusch, A.G.,Zhang, J. Gcn2 structurally mimics and functionally repurposes the HisRS enzyme for the integrated stress response. Proc.Natl.Acad.Sci.USA, 121:e2409628121-e2409628121, 2024 Cited by PubMed: 39163341 DOI: 10.1073/pnas.2409628121 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.69 Å)

Structure validation