2NT7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2nt7 by Molmil](/molmil-images/mine/2nt7) | Crystal structure of PTP1B-inhibitor complex | Descriptor: | Tyrosine-protein phosphatase non-receptor type 1, {[5-(3-{[1-(BENZYLSULFONYL)PIPERIDIN-4-YL]AMINO}PHENYL)-4-BROMO-2-(2H-TETRAZOL-5-YL)-3-THIENYL]OXY}ACETIC ACID | Authors: | Xu, W, Follows, B. | Deposit date: | 2006-11-07 | Release date: | 2007-04-17 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Probing acid replacements of thiophene PTP1B inhibitors. Bioorg.Med.Chem.Lett., 17, 2007
|
|
7UNL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7unl by Molmil](/molmil-images/mine/7unl) | Human TMEM175 in an open state | Descriptor: | Endosomal/lysosomal potassium channel TMEM175, POTASSIUM ION | Authors: | Oh, S, Hite, R.K. | Deposit date: | 2022-04-11 | Release date: | 2022-06-01 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.45 Å) | Cite: | Differential ion dehydration energetics explains selectivity in the non-canonical lysosomal K + channel TMEM175. Elife, 11, 2022
|
|
1NFP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1nfp by Molmil](/molmil-images/mine/1nfp) | |
7UNM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7unm by Molmil](/molmil-images/mine/7unm) | Human TMEM175 in an closed state | Descriptor: | Endosomal/lysosomal potassium channel TMEM175, POTASSIUM ION | Authors: | Oh, S, Hite, R.K. | Deposit date: | 2022-04-11 | Release date: | 2022-06-29 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.61 Å) | Cite: | Differential ion dehydration energetics explains selectivity in the non-canonical lysosomal K + channel TMEM175. Elife, 11, 2022
|
|
4LVT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4lvt by Molmil](/molmil-images/mine/4lvt) | Bcl_2-Navitoclax (ABT-263) Complex | Descriptor: | 4-(4-{[2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-[(4-{[(2R)-4-(morpholin-4-yl)-1-(phenylsulfanyl)butan-2-yl]amino}-3-[(trifluoromethyl)sulfonyl]phenyl)sulfonyl]benzamide, Apoptosis regulator Bcl-2 | Authors: | Park, C.H. | Deposit date: | 2013-07-26 | Release date: | 2013-08-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets. NAT.MED. (N.Y.), 19, 2013
|
|
7XUE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xue by Molmil](/molmil-images/mine/7xue) | |
7XUG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xug by Molmil](/molmil-images/mine/7xug) | |
7XUI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xui by Molmil](/molmil-images/mine/7xui) | |
3EUK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3euk by Molmil](/molmil-images/mine/3euk) | Crystal structure of MukE-MukF(residues 292-443)-MukB(head domain)-ATPgammaS complex, asymmetric dimer | Descriptor: | Chromosome partition protein mukB, Linker, Chromosome partition protein mukE, ... | Authors: | Woo, J.S, Lim, J.H, Shin, H.C, Oh, B.H. | Deposit date: | 2008-10-10 | Release date: | 2009-01-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Structural studies of a bacterial condensin complex reveal ATP-dependent disruption of intersubunit interactions. Cell(Cambridge,Mass.), 136, 2009
|
|
5CUF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5cuf by Molmil](/molmil-images/mine/5cuf) | X-ray crystal structure of SeMet human Sestrin2 | Descriptor: | Sestrin-2 | Authors: | Kim, H, An, S, Ro, S.-H, Lee, J.H, Cho, U.-S. | Deposit date: | 2015-07-24 | Release date: | 2016-01-13 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Janus-faced Sestrin2 controls ROS and mTOR signalling through two separate functional domains. Nat Commun, 6, 2015
|
|
3EUH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3euh by Molmil](/molmil-images/mine/3euh) | Crystal Structure of the MukE-MukF Complex | Descriptor: | Chromosome partition protein mukF, GLYCINE, MukE | Authors: | Suh, M.K, Ku, B, Ha, N.C, Woo, J.S, Oh, B.H. | Deposit date: | 2008-10-10 | Release date: | 2009-01-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural studies of a bacterial condensin complex reveal ATP-dependent disruption of intersubunit interactions. Cell(Cambridge,Mass.), 136, 2009
|
|
7V6U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7v6u by Molmil](/molmil-images/mine/7v6u) | Crystal structure of bacterial peptidase | Descriptor: | 1,2-ETHANEDIOL, D-MALATE, Murein DD-endopeptidase MepS/Murein LD-carboxypeptidase | Authors: | Kim, Y, Lee, W.C. | Deposit date: | 2021-08-20 | Release date: | 2022-08-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.144 Å) | Cite: | The crystal structure of bacterial DD-endopeptidase To be published
|
|
8C8P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8c8p by Molmil](/molmil-images/mine/8c8p) | |
7V6T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7v6t by Molmil](/molmil-images/mine/7v6t) | Crystal structure of bacterial peptidase | Descriptor: | 1,2-ETHANEDIOL, CITRIC ACID, Murein DD-endopeptidase MepS/Murein LD-carboxypeptidase | Authors: | Kim, Y, Lee, W.C. | Deposit date: | 2021-08-20 | Release date: | 2022-08-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.495 Å) | Cite: | Crystal structure of bacterial DD-endopeptidase To be published
|
|
7V6S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7v6s by Molmil](/molmil-images/mine/7v6s) | Crystal structure of bacterial peptidase | Descriptor: | Murein DD-endopeptidase MepS/Murein LD-carboxypeptidase | Authors: | Kim, Y, Lee, W.C. | Deposit date: | 2021-08-20 | Release date: | 2022-08-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.883 Å) | Cite: | The crystal structure fre To be published
|
|
2IG0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ig0 by Molmil](/molmil-images/mine/2ig0) | Structure of 53BP1/methylated histone peptide complex | Descriptor: | Dimethylated Histone H4-K20 peptide, SULFATE ION, Tumor suppressor p53-binding protein 1 | Authors: | Mer, G. | Deposit date: | 2006-09-22 | Release date: | 2007-01-02 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair. Cell(Cambridge,Mass.), 127, 2006
|
|
5V43
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5v43 by Molmil](/molmil-images/mine/5v43) | Engineered human IgG Fc domain aglyco801 | Descriptor: | Ig gamma-1 chain C region | Authors: | Yan, W, Marshall, N, Zhang, Y.J. | Deposit date: | 2017-03-08 | Release date: | 2017-06-21 | Last modified: | 2017-09-27 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | IgG Fc domains that bind C1q but not effector Fc gamma receptors delineate the importance of complement-mediated effector functions. Nat. Immunol., 18, 2017
|
|
3BM2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3bm2 by Molmil](/molmil-images/mine/3bm2) | |
3BM1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3bm1 by Molmil](/molmil-images/mine/3bm1) | |
5V4E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5v4e by Molmil](/molmil-images/mine/5v4e) | Engineered human IgG Fc domain glyco801 (Fc801) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yan, W, Marshall, N, Zhang, Y.J. | Deposit date: | 2017-03-09 | Release date: | 2017-06-21 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.216 Å) | Cite: | IgG Fc domains that bind C1q but not effector Fc gamma receptors delineate the importance of complement-mediated effector functions. Nat. Immunol., 18, 2017
|
|
3TUB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3tub by Molmil](/molmil-images/mine/3tub) | |
3QL0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ql0 by Molmil](/molmil-images/mine/3ql0) | Crystal structure of N23PP/S148A mutant of E. coli dihydrofolate reductase | Descriptor: | Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A. | Deposit date: | 2011-02-02 | Release date: | 2011-04-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis. Science, 332, 2011
|
|
2LN4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ln4 by Molmil](/molmil-images/mine/2ln4) | |
8HIA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hia by Molmil](/molmil-images/mine/8hia) | |
5X42
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5x42 by Molmil](/molmil-images/mine/5x42) | Structure of DotL(590-659)-DotN derived from Legionella pneumophila | Descriptor: | DotN, IcmJ (DotN), IcmO (DotL), ... | Authors: | Kwak, M.J, Kim, J.D, Oh, B.H. | Deposit date: | 2017-02-09 | Release date: | 2017-06-14 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Architecture of the type IV coupling protein complex of Legionella pneumophila Nat Microbiol, 2, 2017
|
|