3QL0
Crystal structure of N23PP/S148A mutant of E. coli dihydrofolate reductase
Summary for 3QL0
| Entry DOI | 10.2210/pdb3ql0/pdb |
| Related | 3QL3 |
| Descriptor | Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total) |
| Functional Keywords | rossmann fold, oxidoreductase |
| Biological source | Escherichia coli |
| Total number of polymer chains | 1 |
| Total formula weight | 19337.24 |
| Authors | Bhabha, G.,Ekiert, D.C.,Wright, P.E.,Wilson, I.A. (deposition date: 2011-02-02, release date: 2011-04-20, Last modification date: 2024-02-21) |
| Primary citation | Bhabha, G.,Lee, J.,Ekiert, D.C.,Gam, J.,Wilson, I.A.,Dyson, H.J.,Benkovic, S.J.,Wright, P.E. A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis. Science, 332:234-238, 2011 Cited by PubMed: 21474759DOI: 10.1126/science.1198542 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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