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7YIR
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BU of 7yir by Molmil
Crystal structure of N-terminal PH domain of ARAP3 protein from human
Descriptor: Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3, DI(HYDROXYETHYL)ETHER
Authors:Zhang, Y.J, Liu, Y.R, Wu, B.
Deposit date:2022-07-18
Release date:2023-05-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:Structural Insights Uncover the Specific Phosphoinositide Recognition by the PH1 Domain of Arap3.
Int J Mol Sci, 24, 2023
7YIS
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BU of 7yis by Molmil
Crystal structure of N-terminal PH domain of ARAP3 protein in complex with inositol 1,3,4,5-tetrakisphosphate
Descriptor: (2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE, Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
Authors:Zhang, Y.J, Liu, Y.R, Wu, B.
Deposit date:2022-07-18
Release date:2023-05-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural Insights Uncover the Specific Phosphoinositide Recognition by the PH1 Domain of Arap3.
Int J Mol Sci, 24, 2023
6K8K
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BU of 6k8k by Molmil
Crystal structure of Arabidopsis thaliana BIC2-CRY2 complex
Descriptor: ADENOSINE MONOPHOSPHATE, Cryptochrome-2, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Wang, X, Ma, L, Guan, Z, Yin, P.
Deposit date:2019-06-12
Release date:2020-05-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights into BIC-mediated inactivation of Arabidopsis cryptochrome 2.
Nat.Struct.Mol.Biol., 27, 2020
5KAE
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BU of 5kae by Molmil
Crystal structure of human PI3K-gamma in complex with quinoline-containing inhibitor 5g
Descriptor: 4-azanyl-6-[[(1~{S})-1-(6-fluoranyl-3-phenyl-4-piperazin-1-ylcarbonyl-quinolin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION
Authors:Whittington, D.A, Tang, J, Yakowec, P.
Deposit date:2016-06-01
Release date:2017-06-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Discovery and in vivo evaluation of the potent and selective PI3K-delta inhibitors AM-0687 and AM-1430
To Be Published
6JYT
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BU of 6jyt by Molmil
Delicate structural coordination of the Severe Acute Respiratory Syndrome coronavirus Nsp13 upon ATP hydrolysis
Descriptor: Helicase, ZINC ION
Authors:Yan, L, Jia, Z.
Deposit date:2019-04-28
Release date:2019-09-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Delicate structural coordination of the Severe Acute Respiratory Syndrome coronavirus Nsp13 upon ATP hydrolysis.
Nucleic Acids Res., 47, 2019
8S5I
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BU of 8s5i by Molmil
Full-length human cystathionine beta-synthase with C-terminal 6xHis-tag, basal state, single particle reconstruction
Descriptor: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE
Authors:McCorvie, T.J, Yue, W.W.
Deposit date:2024-02-23
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Architecture and regulation of filamentous human cystathionine beta-synthase.
Nat Commun, 15, 2024
8S5L
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BU of 8s5l by Molmil
Full-length human cystathionine beta-synthase, basal state, partially degraded tetramer
Descriptor: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE, PYRIDOXAL-5'-PHOSPHATE
Authors:McCorvie, T.J, Yue, W.W.
Deposit date:2024-02-23
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Architecture and regulation of filamentous human cystathionine beta-synthase.
Nat Commun, 15, 2024
8S5J
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BU of 8s5j by Molmil
Full-length human cystathionine beta-synthase, basal state, helical reconstruction
Descriptor: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE
Authors:McCorvie, T.J, Yue, W.W.
Deposit date:2024-02-23
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Architecture and regulation of filamentous human cystathionine beta-synthase.
Nat Commun, 15, 2024
8S5K
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BU of 8s5k by Molmil
Full-length human cystathionine beta-synthase, basal state, single particle reconstruction
Descriptor: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE
Authors:McCorvie, T.J, Yue, W.W.
Deposit date:2024-02-23
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Architecture and regulation of filamentous human cystathionine beta-synthase.
Nat Commun, 15, 2024
8S5H
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BU of 8s5h by Molmil
Full-length human cystathionine beta-synthase with C-terminal 6xHis-tag, basal state, helical reconstruction
Descriptor: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE
Authors:McCorvie, T.J, Yue, W.W.
Deposit date:2024-02-23
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Architecture and regulation of filamentous human cystathionine beta-synthase.
Nat Commun, 15, 2024
8S5M
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BU of 8s5m by Molmil
Full-length human cystathionine beta-synthase with C-terminal 6xHis-tag, SAM bound, activated state, helical reconstruction
Descriptor: Cystathionine beta-synthase, S-ADENOSYLMETHIONINE
Authors:McCorvie, T.J, Yue, W.W.
Deposit date:2024-02-23
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Architecture and regulation of filamentous human cystathionine beta-synthase.
Nat Commun, 15, 2024
6K8I
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BU of 6k8i by Molmil
Crystal structure of Arabidopsis thaliana CRY2
Descriptor: Cryptochrome-2, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Ma, L, Wang, X, Guan, Z, Yin, P.
Deposit date:2019-06-12
Release date:2020-05-13
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.697 Å)
Cite:Structural insights into BIC-mediated inactivation of Arabidopsis cryptochrome 2.
Nat.Struct.Mol.Biol., 27, 2020
6KTO
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BU of 6kto by Molmil
Crystal structure of human SHLD3-C-REV7-O-REV7-SHLD2 complex
Descriptor: Mitotic spindle assembly checkpoint protein MAD2B, Shieldin complex subunit 2, Shieldin complex subunit 3
Authors:Liang, L, Yin, Y.
Deposit date:2019-08-28
Release date:2020-04-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.4497633 Å)
Cite:Molecular basis for assembly of the shieldin complex and its implications for NHEJ.
Nat Commun, 11, 2020
6L0X
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BU of 6l0x by Molmil
The First Tudor Domain of PHF20L1
Descriptor: CITRIC ACID, GLYCEROL, PHD finger protein 20-like protein 1
Authors:Lv, M.Q, Gao, J.
Deposit date:2019-09-27
Release date:2020-09-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Conformational Selection in Ligand Recognition by the First Tudor Domain of PHF20L1.
J Phys Chem Lett, 11, 2020
6L1P
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BU of 6l1p by Molmil
Crystal structure of PHF20L1 in complex with Hit 1
Descriptor: 4-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)phenol, GLYCEROL, PHD finger protein 20-like protein 1, ...
Authors:Lv, M.Q, Gao, J.
Deposit date:2019-09-29
Release date:2020-09-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.231 Å)
Cite:Conformational Selection in Ligand Recognition by the First Tudor Domain of PHF20L1.
J Phys Chem Lett, 11, 2020
6L1C
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BU of 6l1c by Molmil
Crystal Structure Of of PHF20L1 Tudor1 Y24L mutant
Descriptor: GLYCEROL, PHD finger protein 20-like protein 1, SULFATE ION
Authors:Lv, M.Q, Gao, J.
Deposit date:2019-09-28
Release date:2020-09-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Conformational Selection in Ligand Recognition by the First Tudor Domain of PHF20L1.
J Phys Chem Lett, 11, 2020
6L1I
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BU of 6l1i by Molmil
Crystal Structure Of of PHF20L1 Tudor1 Y24W/Y29W mutant
Descriptor: PHD finger protein 20-like protein 1, SULFATE ION
Authors:Lv, M.Q, Gao, J.
Deposit date:2019-09-29
Release date:2020-09-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.849 Å)
Cite:Conformational Selection in Ligand Recognition by the First Tudor Domain of PHF20L1.
J Phys Chem Lett, 11, 2020
6KA6
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BU of 6ka6 by Molmil
Crystal structure of plasmodium lysyl-tRNA synthetase in complex with a cladosporin derivative 1
Descriptor: (3~{S})-3-[[(1~{S},3~{S})-3-methylcyclohexyl]methyl]-6,8-bis(oxidanyl)-3,4-dihydroisochromen-1-one, GLYCEROL, LYSINE, ...
Authors:Zhou, J, Fang, P.
Deposit date:2019-06-21
Release date:2020-04-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.891 Å)
Cite:Atomic Resolution Analyses of Isocoumarin Derivatives for Inhibition of Lysyl-tRNA Synthetase.
Acs Chem.Biol., 15, 2020
6KCN
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BU of 6kcn by Molmil
Crystal structure of plasmodium lysyl-tRNA synthetase in complex with a cladosporin derivative 4
Descriptor: 3-[[(1~{S},3~{S})-3-methylcyclohexyl]methyl]-6,8-bis(oxidanyl)isochromen-1-one, GLYCEROL, LYSINE, ...
Authors:Zhou, J, Fang, P.
Deposit date:2019-06-28
Release date:2020-04-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Atomic Resolution Analyses of Isocoumarin Derivatives for Inhibition of Lysyl-tRNA Synthetase.
Acs Chem.Biol., 15, 2020
6KCT
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BU of 6kct by Molmil
Crystal structure of plasmodium lysyl-tRNA synthetase in complex with a cladosporin derivative 5
Descriptor: 3-(cyclohexylmethyl)-6,8-bis(oxidanyl)isochromen-1-one, LYSINE, Lysine--tRNA ligase
Authors:Zhou, J, Fang, P.
Deposit date:2019-06-29
Release date:2020-04-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Atomic Resolution Analyses of Isocoumarin Derivatives for Inhibition of Lysyl-tRNA Synthetase.
Acs Chem.Biol., 15, 2020
6KBF
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BU of 6kbf by Molmil
Crystal structure of plasmodium lysyl-tRNA synthetase in complex with a cladosporin derivative 3
Descriptor: (3~{S})-3-[[(1~{S},3~{S})-3-methylcyclohexyl]methyl]-6,8-bis(oxidanyl)-3,4-dihydro-2~{H}-isoquinolin-1-one, DIMETHYL SULFOXIDE, GLYCEROL, ...
Authors:Zhou, J, Fang, P.
Deposit date:2019-06-24
Release date:2020-04-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Atomic Resolution Analyses of Isocoumarin Derivatives for Inhibition of Lysyl-tRNA Synthetase.
Acs Chem.Biol., 15, 2020
7Y3I
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BU of 7y3i by Molmil
Structure of DNA bound SALL4
Descriptor: DNA (12-mer), Sal-like protein 4, ZINC ION
Authors:Ru, W, Xu, C.
Deposit date:2022-06-10
Release date:2022-10-26
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural studies of SALL family protein zinc finger cluster domains in complex with DNA reveal preferential binding to an AATA tetranucleotide motif.
J.Biol.Chem., 298, 2022
7Y3L
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BU of 7y3l by Molmil
Structure of SALL3 ZFC4 bound with 12 bp AT-rich dsDNA
Descriptor: DNA (12-mer), Sal-like protein 3, ZINC ION
Authors:Ru, W, Xu, C.
Deposit date:2022-06-11
Release date:2022-10-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural studies of SALL family protein zinc finger cluster domains in complex with DNA reveal preferential binding to an AATA tetranucleotide motif.
J.Biol.Chem., 298, 2022
7Y3M
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BU of 7y3m by Molmil
Structure of SALL4 ZFC1 bound with 16 bp AT-rich dsDNA
Descriptor: DNA (16-mer), Sal-like protein 4, ZINC ION
Authors:Ru, W, Xu, C.
Deposit date:2022-06-11
Release date:2022-10-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.723 Å)
Cite:Structural studies of SALL family protein zinc finger cluster domains in complex with DNA reveal preferential binding to an AATA tetranucleotide motif.
J.Biol.Chem., 298, 2022
7Y3K
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BU of 7y3k by Molmil
Structure of SALL4 ZFC4 bound with 16 bp AT-rich dsDNA
Descriptor: DNA (16-mer), Sal-like protein 4, ZINC ION
Authors:Ru, W, Xu, C.
Deposit date:2022-06-11
Release date:2022-10-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Structural studies of SALL family protein zinc finger cluster domains in complex with DNA reveal preferential binding to an AATA tetranucleotide motif.
J.Biol.Chem., 298, 2022

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