8S5I

Full-length human cystathionine beta-synthase with C-terminal 6xHis-tag, basal state, single particle reconstruction

Summary for 8S5I

• Entry DOI: 10.2210/pdb8s5i/pdb
• EMDB information: 19736
• Descriptor: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE (2 entities in total)
• Functional Keywords: filament, allostery, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 6
• Total formula weight: 374886.23

Authors

McCorvie, T.J.,Yue, W.W. (deposition date: 2024-02-23, release date: 2024-04-17)

• Primary citation: McCorvie, T.J.,Adamoski, D.,Machado, R.A.C.,Tang, J.,Bailey, H.J.,Ferreira, D.S.M.,Strain-Damerell, C.,Basle, A.,Ambrosio, A.L.B.,Dias, S.M.G.,Yue, W.W.; Architecture and regulation of filamentous human cystathionine beta-synthase.; Nat Commun, 15:2931-2931, 2024; PubMed: 38575566; DOI: 10.1038/s41467-024-46864-x

Experimental method

ELECTRON MICROSCOPY (3.1 Å)