6KTO

Crystal structure of human SHLD3-C-REV7-O-REV7-SHLD2 complex

Summary for 6KTO

Entry DOI	10.2210/pdb6kto/pdb
Descriptor	Mitotic spindle assembly checkpoint protein MAD2B, Shieldin complex subunit 3, Shieldin complex subunit 2 (3 entities in total)
Functional Keywords	shieldin, complex, conformational dimer, nhej, replication
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	65731.15
Authors	Liang, L.,Yin, Y. (deposition date: 2019-08-28, release date: 2020-04-29, Last modification date: 2023-11-22)
Primary citation	Liang, L.,Feng, J.,Zuo, P.,Yang, J.,Lu, Y.,Yin, Y. Molecular basis for assembly of the shieldin complex and its implications for NHEJ. Nat Commun, 11:1972-1972, 2020 Cited by PubMed: 32332881 DOI: 10.1038/s41467-020-15879-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.44976331487 Å)

Structure validation