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2RB6
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BU of 2rb6 by Molmil
X-Ray structure of the protein Q8EI81. Northeast Structural Genomics Consortium target SoR78A
Descriptor: Uncharacterized protein
Authors:Kuzin, A.P, Su, M, Seetharaman, J, Vorobiev, S.M, Wang, H, Mao, L, Cunningham, K, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2007-09-18
Release date:2007-10-23
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:X-Ray structure of the protein Q8EI81.
To be Published
2RAL
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BU of 2ral by Molmil
Crystal Structure Analysis of double cysteine mutant of S.epidermidis adhesin SdrG: Evidence for the Dock,Lock and Latch ligand binding mechanism
Descriptor: Serine-aspartate repeat-containing protein G
Authors:Ponnuraj, K, Sthanam, N, Bowden, M.G, Hook, M.
Deposit date:2007-09-17
Release date:2007-11-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Evidence for the "dock, lock, and latch" ligand binding mechanism of the staphylococcal microbial surface component recognizing adhesive matrix molecules (MSCRAMM) SdrG.
J.Biol.Chem., 283, 2008
4URY
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BU of 4ury by Molmil
The crystal structure of H-Ras and SOS in complex with ligands
Descriptor: GTPASE HRAS, N-[(4-aminophenyl)sulfonyl]cyclopropanecarboxamide, SON OF SEVENLESS HOMOLOG 1
Authors:Winter, J.J.G, Anderson, M, Blades, K, Brassington, C, Breeze, A.L, Chresta, C, Embrey, K, Fairley, G, Faulder, P, Finlay, M.R.V, Kettle, J.G, Nowak, T, Overman, R, Patel, S.J, Perkins, P, Spadola, L, Tart, J, Tucker, J, Wrigley, G.
Deposit date:2014-07-02
Release date:2015-03-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Small Molecule Binding Sites on the Ras:SOS Complex Can be Exploited for Inhibition of Ras Activation.
J.Med.Chem., 58, 2015
2RD4
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BU of 2rd4 by Molmil
Design of specific inhibitors of Phospholipase A2: Crystal structure of the complex of phospholipase A2 with pentapeptide Leu-Val-Phe-Phe-Ala at 2.9 A resolution
Descriptor: CALCIUM ION, Phospholipase A2 isoform 1, Phospholipase A2 isoform 2, ...
Authors:Mirza, Z, Kaur, A, Singh, N, Sinha, M, Sharma, S, Srinivasan, A, Kaur, P, Singh, T.P.
Deposit date:2007-09-21
Release date:2007-10-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Design of specific inhibitors of Phospholipase A2: Crystal structure of the complex of phospholipase A2 with pentapeptide Leu-Val-Phe-Phe-Ala at 2.9 A resolution
To be Published
4V0T
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BU of 4v0t by Molmil
Monomeric pseudorabies virus protease pUL26N at 2.1 A resolution
Descriptor: UL26
Authors:Zuehlsdorf, M, Werten, S, Palm, G.J, Hinrichs, W.
Deposit date:2014-09-18
Release date:2015-07-15
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Dimerization-Induced Allosteric Changes of the Oxyanion-Hole Loop Activate the Pseudorabies Virus Assemblin Pul26N, a Herpesvirus Serine Protease
Plos Pathog., 11, 2015
4V4T
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BU of 4v4t by Molmil
Crystal structure of the whole ribosomal complex with a stop codon in the A-site.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Petry, S, Brodersen, D.E, Murphy IV, F.V, Dunham, C.M, Selmer, M, Tarry, M.J, Kelley, A.C, Ramakrishnan, V.
Deposit date:2005-10-12
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (6.46 Å)
Cite:Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon.
Cell(Cambridge,Mass.), 123, 2005
4W6W
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BU of 4w6w by Molmil
Co-complex structure of the lectin domain of F18 fimbrial adhesin FedF with inhibitory nanobody NbFedF6
Descriptor: F18 fimbrial adhesin AC, NbFedF6
Authors:Moonens, K, De Kerpel, M, Annelies, C, Cox, E, Pardon, E, Remaut, H, De Greve, H.
Deposit date:2014-08-21
Release date:2014-12-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Nanobody Mediated Inhibition of Attachment of F18 Fimbriae Expressing Escherichia coli.
Plos One, 9, 2014
2RK4
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BU of 2rk4 by Molmil
Structure of M26I DJ-1
Descriptor: Protein DJ-1
Authors:Lakshminarasimhan, M, Maldonado, M.T, Zhou, W, Fink, A.L, Wilson, M.A.
Deposit date:2007-10-16
Release date:2008-01-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Structural Impact of Three Parkinsonism-Associated Missense Mutations on Human DJ-1.
Biochemistry, 47, 2008
2R6T
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BU of 2r6t by Molmil
Structure of a R132K variant PduO-type ATP:co(I)rrinoid adenosyltransferase from Lactobacillus reuteri complexed with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cobalamin adenosyltransferase PduO-like protein, MAGNESIUM ION
Authors:St Maurice, M, Mera, P.E, Escalante-Semerena, J.C, Rayment, I.
Deposit date:2007-09-06
Release date:2007-12-18
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structural and functional analyses of the human-type corrinoid adenosyltransferase (PduO) from Lactobacillus reuteri.
Biochemistry, 46, 2007
2RM4
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BU of 2rm4 by Molmil
Solution Structure of the LSM Domain of Dm EDC3 (Enhancer of DECAPPING 3)
Descriptor: CG6311-PB
Authors:Truffault, V, Coles, M, Tritschler, F.
Deposit date:2007-09-20
Release date:2007-10-30
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:A divergent Sm fold in EDC3 proteins mediates DCP1 binding and P-body targeting
Mol.Cell.Biol., 27, 2007
2RO3
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BU of 2ro3 by Molmil
RDC-refined Solution Structure of the N-terminal DNA Recognition Domain of the Bacillus subtilis Transition-state Regulator Abh
Descriptor: Putative transition state regulator abh
Authors:Sullivan, D.M, Bobay, B.G, Douglas, K.J, Thompson, R.J, Rance, M, Strauch, M.A, Cavanagh, J.
Deposit date:2008-03-08
Release date:2008-11-11
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Insights into the nature of DNA binding of AbrB-like transcription factors
Structure, 16, 2008
4V69
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BU of 4v69 by Molmil
Ternary complex-bound E.coli 70S ribosome.
Descriptor: 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Villa, E, Sengupta, J, Trabuco, L.G, LeBarron, J, Baxter, W.T, Shaikh, T.R, Grassucci, R.A, Nissen, P, Ehrenberg, M, Schulten, K, Frank, J.
Deposit date:2008-12-11
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis
Proc.Natl.Acad.Sci.USA, 106, 2009
4W6X
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BU of 4w6x by Molmil
Co-complex structure of the lectin domain of F18 fimbrial adhesin FedF with inhibitory nanobody NbFedF7
Descriptor: F18 fimbrial adhesin AC, Nanobody NbFedF7
Authors:Moonens, K, De Kerpel, M, Coddens, A, Cox, E, Pardon, E, Remaut, H, De Greve, H.
Deposit date:2014-08-21
Release date:2014-12-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Nanobody Mediated Inhibition of Attachment of F18 Fimbriae Expressing Escherichia coli.
Plos One, 9, 2014
2RF8
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BU of 2rf8 by Molmil
Crystal Structure of the mutant C2A conjugated bile acid hydrolase from Clostridium perfringens
Descriptor: Choloylglycine hydrolase, GLYCEROL
Authors:Rossmann, M, Saenger, W.
Deposit date:2007-09-28
Release date:2008-10-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for the catalytic activity and processing of the conjugated bile salt hydrolase from Clostridium perfringens
To be Published
2R98
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BU of 2r98 by Molmil
Crystal Structure of N-acetylglutamate synthase (selenoMet substituted) from Neisseria gonorrhoeae
Descriptor: ACETYL COENZYME *A, Putative acetylglutamate synthase
Authors:Shi, D, Sagar, V, Jin, Z, Yu, X, Caldovic, L, Morizono, H, Allewell, N.M, Tuchman, M.
Deposit date:2007-09-12
Release date:2008-01-15
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The crystal structure of N-acetyl-L-glutamate synthase from Neisseria gonorrhoeae provides insights into mechanisms of catalysis and regulation.
J.Biol.Chem., 283, 2008
2R9G
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BU of 2r9g by Molmil
Crystal structure of the C-terminal fragment of AAA ATPase from Enterococcus faecium
Descriptor: AAA ATPase, central region, ACETATE ION, ...
Authors:Ramagopal, U.A, Patskovsky, Y, Bonanno, J.B, Shi, W, Toro, R, Meyer, A.J, Rutter, M, Wu, B, Groshong, C, Gheyi, T, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2007-09-12
Release date:2007-10-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Crystal Structure of the C-Terminal Domain of AAA ATPase from Enterococcus faecium.
To be Published
4WBA
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BU of 4wba by Molmil
Q/E mutant SA11 NSP4_CCD
Descriptor: GLYCEROL, Non-structural glycoprotein NSP4, PHOSPHATE ION
Authors:Viskovska, M, Sastri, N.P, Hyser, J.M, Tanner, M.R, Horton, L.B, Sankaran, B, Prasad, B.V.V, Estes, M.K.
Deposit date:2014-09-02
Release date:2014-09-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Structural Plasticity of the Coiled-Coil Domain of Rotavirus NSP4.
J.Virol., 88, 2014
2RLC
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BU of 2rlc by Molmil
Crystal Structure of the Conjugated Bile Acid Hydrolase from Clostridium perfringens in Complex with Reaction Products Glycine and Cholate
Descriptor: CHOLIC ACID, Choloylglycine hydrolase, GLYCINE, ...
Authors:Rossmann, M, Saenger, W.
Deposit date:2007-10-18
Release date:2009-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of choloyl glycine hydrolase from Clostridium perfringens
To be Published
2RLT
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BU of 2rlt by Molmil
phosphorylated CPI-17 (22-120)
Descriptor: Protein phosphatase 1 regulatory subunit 14A
Authors:Eto, M.
Deposit date:2007-08-11
Release date:2008-07-15
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Phosphorylation-induced conformational switching of CPI-17 produces a potent myosin phosphatase inhibitor.
Structure, 15, 2007
2RM5
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BU of 2rm5 by Molmil
Glutathione peroxidase-type tryparedoxin peroxidase, oxidized form
Descriptor: Glutathione peroxidase-like protein
Authors:Melchers, J, Feher, K, Diechtierow, M, Krauth-Siegel, L, Tews, I, Muhle-Goll, C.
Deposit date:2007-10-03
Release date:2008-07-29
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Structural basis for a distinct catalytic mechanism in Trypanosoma brucei tryparedoxin peroxidase
J.Biol.Chem., 283, 2008
2REX
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BU of 2rex by Molmil
Crystal structure of the effector domain of PLXNB1 bound with Rnd1 GTPase
Descriptor: CALCIUM ION, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Tong, Y, Tempel, W, Shen, L, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2007-09-27
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the effector domain of PLXNB1 bound with Rnd1 GTPase.
To be Published
4WB5
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BU of 4wb5 by Molmil
Crystal structure of human cAMP-dependent protein kinase A (catalytic alpha subunit)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PKI (5-24), ...
Authors:Cheung, J, Ginter, C, Cassidy, M, Franklin, M.C, Rudolph, M.J, Hendrickson, W.A.
Deposit date:2014-09-02
Release date:2015-01-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.641 Å)
Cite:Structural insights into mis-regulation of protein kinase A in human tumors.
Proc.Natl.Acad.Sci.USA, 112, 2015
4WB4
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BU of 4wb4 by Molmil
wt SA11 NSP4_CCD
Descriptor: CALCIUM ION, Non-structural glycoprotein NSP4
Authors:Viskovska, M, Sastri, N.P, Hyser, J.M, Tanner, M.R, Horton, L.B, Sankaran, B, Prasad, B.V.V, Estes, M.K.
Deposit date:2014-09-02
Release date:2014-09-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structural Plasticity of the Coiled-Coil Domain of Rotavirus NSP4.
J.Virol., 88, 2014
2RRD
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BU of 2rrd by Molmil
Structure of HRDC domain from human Bloom syndrome protein, BLM
Descriptor: HRDC domain from Bloom syndrome protein
Authors:Sato, A, Mishima, M, Nagai, A, Kim, S.Y, Ito, Y, Hakoshima, T, Jee, J.G, Kitano, K.
Deposit date:2010-07-19
Release date:2010-09-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of the HRDC domain of human Bloom syndrome protein BLM
J.Biochem., 148, 2010
4WBH
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BU of 4wbh by Molmil
STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM I APO - 2.2A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Protein notum homolog, ...
Authors:Zebisch, M, Jones, E.Y.
Deposit date:2014-09-03
Release date:2015-02-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Notum deacylates Wnt proteins to suppress signalling activity
Nature, 519, 2015

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