2RD4

Design of specific inhibitors of Phospholipase A2: Crystal structure of the complex of phospholipase A2 with pentapeptide Leu-Val-Phe-Phe-Ala at 2.9 A resolution

Summary for 2RD4

• Entry DOI: 10.2210/pdb2rd4/pdb
• Related: 1S6B
• Descriptor: Phospholipase A2 isoform 1, Phospholipase A2 isoform 2, pentapeptide inhibitor, ... (5 entities in total)
• Functional Keywords: phospholipase a2, peptide inhibitor, complex, calcium, hydrolase, lipid degradation, metal-binding, secreted
• Biological source: Naja sagittifera; More
• Cellular location: Secreted: P60043 P60044
• Total number of polymer chains: 3
• Total formula weight: 27185.25

Authors

Mirza, Z.,Kaur, A.,Singh, N.,Sinha, M.,Sharma, S.,Srinivasan, A.,Kaur, P.,Singh, T.P. (deposition date: 2007-09-21, release date: 2007-10-09, Last modification date: 2024-11-06)

• Primary citation: Mirza, Z.,Kaur, A.,Singh, N.,Sinha, M.,Sharma, S.,Srinivasan, A.,Kaur, P.,Singh, T.P.; Design of specific inhibitors of Phospholipase A2: Crystal structure of the complex of phospholipase A2 with pentapeptide Leu-Val-Phe-Phe-Ala at 2.9 A resolution; To be Published,

Experimental method

X-RAY DIFFRACTION (2.97 Å)