2RD4
Design of specific inhibitors of Phospholipase A2: Crystal structure of the complex of phospholipase A2 with pentapeptide Leu-Val-Phe-Phe-Ala at 2.9 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phospholipase A2 isoform 1 | polymer | 119 | 13220.7 | 1 | UniProt (P60043) Pfam (PF00068) | Naja sagittifera | Phosphatidylcholine 2-acylhydrolase, Fragment |
| 2 | B (B) | Phospholipase A2 isoform 2 | polymer | 119 | 13288.7 | 1 | UniProt (P60044) Pfam (PF00068) | Naja sagittifera | Phosphatidylcholine 2-acylhydrolase, Fragment |
| 3 | C (C) | pentapeptide inhibitor | polymer | 5 | 595.7 | 1 | |||
| 4 | D, E (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 58 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 27105.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 80.2 | |
| All* | Total formula weight | 27185.3 |
