8YUU
 
 | | Cryo-EM structure of the histamine-bound H3R-Gi complex | | Descriptor: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Shen, Q, Tang, X, Wen, X, Cheng, S, Xiao, P, Zang, S, Shen, D, Jiang, L, Zheng, Y, Zhang, H, Xu, H, Mao, C, Zhang, M, Hu, W, Sun, J, Chen, Z, Zhang, Y. | | Deposit date: | 2024-03-27 | | Release date: | 2024-06-05 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Molecular Determinant Underlying Selective Coupling of Primary G-Protein by Class A GPCRs.
Adv Sci, 11, 2024
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8YUT
 | | Cryo-EM structure of the amthamine-bound H2R-Gs complex | | Descriptor: | 5-(2-azanylethyl)-4-methyl-1,3-thiazol-2-amine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Shen, Q, Tang, X, Wen, X, Cheng, S, Xiao, P, Zang, S, Shen, D, Jiang, L, Zheng, Y, Zhang, H, Xu, H, Mao, C, Zhang, M, Hu, W, Sun, J, Chen, Z, Zhang, Y. | | Deposit date: | 2024-03-27 | | Release date: | 2024-06-05 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Molecular Determinant Underlying Selective Coupling of Primary G-Protein by Class A GPCRs.
Adv Sci, 11, 2024
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8I3E
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8YM2
 | | Crystal structure of AIDA-1 PTB domain in complex with SynGAP NPxF motif | | Descriptor: | Ankyrin repeat and sterile alpha motif domain-containing protein 1B, Ras/Rap GTPase-activating protein SynGAP | | Authors: | Wang, X, Wang, Y, Cai, Q, Zhang, M. | | Deposit date: | 2024-03-08 | | Release date: | 2024-05-29 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | AIDA-1/ANKS1B Binds to the SynGAP Family RasGAPs with High Affinity and Specificity.
J.Mol.Biol., 436, 2024
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3E95
 | | Crystal Structure of the Plasmodium Falciparum ubiquitin conjugating enzyme complex, PfUBC13-PfUev1a | | Descriptor: | UNKNOWN ATOM OR ION, Ubiquitin carrier protein, Ubiquitin-conjugating enzyme E2 | | Authors: | Wernimont, A.K, Lam, A, Ali, A, Brokx, S, Lin, Y.H, Zhao, Y, Lew, J, Ravichandran, M, Wasney, G, Vedadi, M, Kozieradzki, I, Schapira, M, Bochkarev, A, Wilkstrom, M, BOuntra, C, Arrowsmith, C.H, Edwards, A.M, Hui, R, Qiu, W, Brand, V.B, Structural Genomics Consortium (SGC) | | Deposit date: | 2008-08-21 | | Release date: | 2008-09-30 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal Structure of the Plasmodium Falciparum ubiquitin conjugating enzyme complex, PfUBC13-PfUev1a
TO BE PUBLISHED
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3WYO
 | | Heterodimeric myoglobin formed by domain swapping | | Descriptor: | Myoglobin, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Lin, Y.W, Nagao, S, Zhang, M, Shomura, Y, Higuchi, Y, Hirota, S. | | Deposit date: | 2014-09-04 | | Release date: | 2014-11-19 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Rational design of heterodimeric protein using domain swapping for myoglobin.
Angew.Chem.Int.Ed.Engl., 54, 2015
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3EPU
 | | Crystal Structure of STM2138, a novel virulence chaperone in Salmonella | | Descriptor: | STM2138 Virulence Chaperone | | Authors: | Zhang, K, Andres, S.N, Hannemann, M, Coombes, B, Junop, M. | | Deposit date: | 2008-09-30 | | Release date: | 2009-09-29 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural analysis and quantitative proteomic
interactome of a novel virulence chaperone in Salmonella
To be Published
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4RGJ
 | | Apo crystal structure of CDPK4 from Plasmodium falciparum, PF3D7_0717500 | | Descriptor: | Calcium-dependent protein kinase 4 | | Authors: | Wernimont, A.K, Walker, J.R, Hutchinson, A, Seitova, A, He, H, Loppnau, P, Neculai, M, Amani, M, Lin, Y.H, Ravichandran, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hui, R, Lovato, D.V, Structural Genomics Consortium (SGC) | | Deposit date: | 2014-09-30 | | Release date: | 2014-10-29 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.303 Å) | | Cite: | Apo crystal structure of CDPK4 from Plasmodium falciparum, PF3D7_0717500
To be Published
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3E22
 | | Tubulin-colchicine-soblidotin: Stathmin-like domain complex | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Cormier, A, Marchand, M, Ravelli, R.B, Knossow, M, Gigant, B. | | Deposit date: | 2008-08-05 | | Release date: | 2008-10-21 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Structural insight into the inhibition of tubulin by vinca domain peptide ligands
Embo Rep., 9, 2008
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4R8G
 | | Crystal Structure of Myosin-1c tail in complex with Calmodulin | | Descriptor: | Calmodulin, SULFATE ION, Unconventional myosin-Ic | | Authors: | Lu, Q, Li, J, Ye, F, Zhang, M. | | Deposit date: | 2014-09-02 | | Release date: | 2014-12-03 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (3.503 Å) | | Cite: | Structure of myosin-1c tail bound to calmodulin provides insights into calcium-mediated conformational coupling.
Nat.Struct.Mol.Biol., 22, 2015
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7SWL
 | | CryoEM structure of the N-terminal-deleted Rix7 AAA-ATPase | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Kocaman, S, Stanley, R.E, Lo, Y.H, Krahn, J, Dandey, V.P, Sobhany, M, Petrovich, M, Williams, J.G, Deterding, L.J, Borgnia, M.J, Etigunta, S. | | Deposit date: | 2021-11-20 | | Release date: | 2022-03-02 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.88 Å) | | Cite: | Communication network within the essential AAA-ATPase Rix7 drives ribosome assembly.
Pnas Nexus, 1, 2022
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7T0V
 | | CryoEM structure of the crosslinked Rix7 AAA-ATPase | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Kocaman, S, Stanley, R.E, Lo, Y.H, Krahn, J, Dandey, V.P, Sobhany, M, Petrovich, M, Williams, J.G, Deterding, L.J, Borgnia, M.J, Etigunta, S. | | Deposit date: | 2021-11-30 | | Release date: | 2022-03-02 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.67 Å) | | Cite: | Communication network within the essential AAA-ATPase Rix7 drives ribosome assembly.
Pnas Nexus, 1, 2022
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6KG6
 | | Crystal structure of MavC/UBE2N-Ub complex | | Descriptor: | MavC, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 N | | Authors: | Wang, Y, Huang, Y, Chang, M, Feng, Y. | | Deposit date: | 2019-07-10 | | Release date: | 2020-04-01 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.39 Å) | | Cite: | Structural insights into the mechanism and inhibition of transglutaminase-induced ubiquitination by the Legionella effector MavC.
Nat Commun, 11, 2020
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6Q8Z
 | | Structure of human galactokinase 1 bound with N-(Cyclobutylmethyl)-1,5-dimethyl-1H-pyrazole-4-carboxamide | | Descriptor: | 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, Galactokinase, beta-D-galactopyranose, ... | | Authors: | Mackinnon, S.R, Bezerra, G.A, Zhang, M, Foster, W, Krojer, T, Brandao-Neto, J, Douangamath, A, Arrowsmith, C, Edwards, A, Bountra, C, Brennan, P, Lai, K, Yue, W.W. | | Deposit date: | 2018-12-16 | | Release date: | 2019-01-23 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of human galactokinase 1 bound with N-(Cyclobutylmethyl)-1,5-dimethyl-1H-pyrazole-4-carboxamide
To Be Published
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6IRE
 | | Complex structure of INAD PDZ45 and NORPA CC-PBM | | Descriptor: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase, Inactivation-no-after-potential D protein | | Authors: | Ye, F, Li, J, Deng, X, Liu, W, Zhang, M. | | Deposit date: | 2018-11-12 | | Release date: | 2019-01-23 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | An unexpected INAD PDZ tandem-mediated plc beta binding in Drosophila photo receptors.
Elife, 7, 2018
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6IRC
 | | C-terminal domain of Drosophila phospholipase b NORPA, methylated | | Descriptor: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase | | Authors: | Ye, F, Li, J, Huang, Y, Liu, W, Zhang, M. | | Deposit date: | 2018-11-12 | | Release date: | 2019-01-02 | | Last modified: | 2020-10-28 | | Method: | X-RAY DIFFRACTION (3.538 Å) | | Cite: | An unexpected INAD PDZ tandem-mediated plc beta binding in Drosophila photo receptors.
Elife, 7, 2018
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6IRB
 | | C-terminal coiled coil domain of Drosophila phospholipase C beta NORPA, selenomethionine | | Descriptor: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase | | Authors: | Ye, F, Li, J, Huang, Y, Liu, W, Zhang, M. | | Deposit date: | 2018-11-12 | | Release date: | 2019-01-02 | | Last modified: | 2020-10-28 | | Method: | X-RAY DIFFRACTION (2.661 Å) | | Cite: | An unexpected INAD PDZ tandem-mediated plc beta binding in Drosophila photo receptors.
Elife, 7, 2018
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6IRR
 | | Solution structure of DISC1/ATF4 complex | | Descriptor: | Disrupted in schizophrenia 1 homolog,Cyclic AMP-dependent transcription factor ATF-4 | | Authors: | Ye, F, Yu, C, Zhang, M. | | Deposit date: | 2018-11-14 | | Release date: | 2019-09-25 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural interaction between DISC1 and ATF4 underlying transcriptional and synaptic dysregulation in an iPSC model of mental disorders.
Mol. Psychiatry, 2019
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6J68
 | | Structure of KIBRA and LATS1 Complex | | Descriptor: | Peptide from Serine/threonine-protein kinase LATS1, Protein KIBRA | | Authors: | Lin, Z, Yang, Z, Ji, Z, Zhang, M. | | Deposit date: | 2019-01-14 | | Release date: | 2019-09-25 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.495 Å) | | Cite: | Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity.
Elife, 8, 2019
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1GGZ
 | | CRYSTAL STRUCTURE OF THE CALMODULIN-LIKE PROTEIN (HCLP) FROM HUMAN EPITHELIAL CELLS | | Descriptor: | CALCIUM ION, CALMODULIN-RELATED PROTEIN NB-1 | | Authors: | Han, B.-G, Han, M, Sui, H, Yaswen, P, Walian, P.J, Jap, B.K. | | Deposit date: | 2000-10-13 | | Release date: | 2002-06-05 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal structure of human calmodulin-like protein: insights into its functional role.
FEBS Lett., 521, 2002
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8OWJ
 | | Lipidic amyloid-beta(1-40) fibril - polymorph L2-L2 | | Descriptor: | Amyloid-beta A4 protein | | Authors: | Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. | | Deposit date: | 2023-04-28 | | Release date: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.75 Å) | | Cite: | Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40).
Nat Commun, 15, 2024
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8OVM
 | | Lipidic amyloid-beta(1-40) fibril - polymorph L2 | | Descriptor: | Amyloid-beta A4 protein | | Authors: | Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. | | Deposit date: | 2023-04-26 | | Release date: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.24 Å) | | Cite: | Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40).
Nat Commun, 15, 2024
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8OVK
 | | Lipidic amyloid-beta(1-40) fibril - polymorph L1 | | Descriptor: | Amyloid-beta A4 protein | | Authors: | Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. | | Deposit date: | 2023-04-26 | | Release date: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (2.88 Å) | | Cite: | Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40).
Nat Commun, 15, 2024
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8OWE
 | | Lipidic amyloid-beta(1-40) fibril - polymorph L2-L3 | | Descriptor: | Amyloid-beta A4 protein | | Authors: | Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. | | Deposit date: | 2023-04-27 | | Release date: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.75 Å) | | Cite: | Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40).
Nat Commun, 15, 2024
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8OWK
 | | Lipidic amyloid-beta(1-40) fibril - polymorph L3-L3 | | Descriptor: | Amyloid-beta A4 protein | | Authors: | Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. | | Deposit date: | 2023-04-28 | | Release date: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.86 Å) | | Cite: | Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40).
Nat Commun, 15, 2024
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