6IRR

Solution structure of DISC1/ATF4 complex

Summary for 6IRR

• Entry DOI: 10.2210/pdb6irr/pdb
• Descriptor: Disrupted in schizophrenia 1 homolog,Cyclic AMP-dependent transcription factor ATF-4 (1 entity in total)
• Functional Keywords: scaffold protein, psychiatric disorder, coiled coil, structural protein
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 1
• Total formula weight: 14565.50

Authors

Ye, F.,Yu, C.,Zhang, M. (deposition date: 2018-11-14, release date: 2019-09-25, Last modification date: 2023-06-14)

• Primary citation: Wang, X.,Ye, F.,Wen, Z.,Guo, Z.,Yu, C.,Huang, W.K.,Rojas Ringeling, F.,Su, Y.,Zheng, W.,Zhou, G.,Christian, K.M.,Song, H.,Zhang, M.,Ming, G.L.; Structural interaction between DISC1 and ATF4 underlying transcriptional and synaptic dysregulation in an iPSC model of mental disorders.; Mol. Psychiatry, 2019; PubMed: 31444471; DOI: 10.1038/s41380-019-0485-2

Experimental method

SOLUTION NMR