6IRR
Solution structure of DISC1/ATF4 complex
Summary for 6IRR
Entry DOI | 10.2210/pdb6irr/pdb |
Descriptor | Disrupted in schizophrenia 1 homolog,Cyclic AMP-dependent transcription factor ATF-4 (1 entity in total) |
Functional Keywords | scaffold protein, psychiatric disorder, coiled coil, structural protein |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 1 |
Total formula weight | 14565.50 |
Authors | |
Primary citation | Wang, X.,Ye, F.,Wen, Z.,Guo, Z.,Yu, C.,Huang, W.K.,Rojas Ringeling, F.,Su, Y.,Zheng, W.,Zhou, G.,Christian, K.M.,Song, H.,Zhang, M.,Ming, G.L. Structural interaction between DISC1 and ATF4 underlying transcriptional and synaptic dysregulation in an iPSC model of mental disorders. Mol. Psychiatry, 2019 Cited by PubMed: 31444471DOI: 10.1038/s41380-019-0485-2 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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