3UO1
| Structure of a monoclonal antibody complexed with its MHC-I antigen | Descriptor: | ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, 64-3-7 L CHAIN, ... | Authors: | Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K. | Deposit date: | 2011-11-16 | Release date: | 2012-07-25 | Last modified: | 2012-08-01 | Method: | X-RAY DIFFRACTION (1.641 Å) | Cite: | The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics. J.Immunol., 189, 2012
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3UYR
| Structure of a monoclonal antibody complexed with its MHC-I antigen | Descriptor: | 1,2-ETHANEDIOL, H-2 class I histocompatibility antigen, L-D alpha chain, ... | Authors: | Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K. | Deposit date: | 2011-12-06 | Release date: | 2012-07-25 | Last modified: | 2012-08-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics. J.Immunol., 189, 2012
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3V4U
| Structure of a monoclonal antibody complexed with its MHC-I antigen | Descriptor: | ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, 64-3-7 L CHAIN, ... | Authors: | Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K. | Deposit date: | 2011-12-15 | Release date: | 2012-07-25 | Last modified: | 2012-08-01 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics. J.Immunol., 189, 2012
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4G59
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7KGK
| Crystal structure of synthetic nanobody (Sb16) complexes with SARS-CoV-2 receptor binding domain | Descriptor: | Sb16, Sybody-16, Synthetic Nanobody, ... | Authors: | Jiang, J, Ahmad, J, Natarajan, K, Boyd, L.F, Margulies, D.H. | Deposit date: | 2020-10-16 | Release date: | 2021-02-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction. J.Biol.Chem., 297, 2021
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7KGJ
| Crystal structure of synthetic nanobody (Sb45) complexes with SARS-CoV-2 receptor binding domain | Descriptor: | Sb45, Sybody-45, Synthetic Nanobody, ... | Authors: | Jiang, J, Ahmad, J, Natarajan, K, Boyd, L.F, Margulies, D.H. | Deposit date: | 2020-10-16 | Release date: | 2021-02-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction. J.Biol.Chem., 297, 2021
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7KLW
| Crystal structure of synthetic nanobody (Sb45+Sb68) complexes with SARS-CoV-2 receptor binding domain | Descriptor: | SB45, Synthetic Nanobody, SB68, ... | Authors: | Jiang, J, Ahmad, J, Natarajan, K, Boyd, L.F, Margulies, D.H. | Deposit date: | 2020-11-01 | Release date: | 2021-02-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction. J.Biol.Chem., 297, 2021
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1FM5
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1B88
| V-ALPHA 2.6 MOUSE T CELL RECEPTOR (TCR) DOMAIN | Descriptor: | T CELL RECEPTOR V-ALPHA DOMAIN | Authors: | Plaksin, D, Chacko, S, Navaza, J, Margulies, D.H, Padlan, E.A. | Deposit date: | 1999-02-09 | Release date: | 1999-02-16 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The X-ray crystal structure of a Valpha2.6Jalpha38 mouse T cell receptor domain at 2.5 A resolution: alternate modes of dimerization and crystal packing. J.Mol.Biol., 289, 1999
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1DDH
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1U58
| Crystal structure of the murine cytomegalovirus MHC-I homolog m144 | Descriptor: | MHC-I homolog m144, beta-2-microglobulin | Authors: | Natarajan, K, Hicks, A, Robinson, H, Guan, R, Margulies, D.H. | Deposit date: | 2004-07-27 | Release date: | 2005-07-19 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the murine cytomegalovirus MHC-I homolog m144. J.Mol.Biol., 358, 2006
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1P1Z
| X-RAY CRYSTAL STRUCTURE OF THE LECTIN-LIKE NATURAL KILLER CELL RECEPTOR LY-49C BOUND TO ITS MHC CLASS I LIGAND H-2Kb | Descriptor: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-B alpha chain, ... | Authors: | Dimasi, N, Natarajan, K, Rangjin, G, Dam, J, Margulies, D.H, Mariuzza, R.A. | Deposit date: | 2003-04-14 | Release date: | 2003-11-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.26 Å) | Cite: | Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2K(b). Nat.Immunol., 4, 2003
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3E6F
| MHC CLASS I H-2Dd Heavy chain complexed with Beta-2 Microglobulin and a variant peptide, PA9, from the Human immunodeficiency virus (BaL) envelope glycoprotein 120 | Descriptor: | BETA-2 MICROGLOBULIN, Envelope glycoprotein 9-residue peptide, H-2 class I histocompatibility antigen, ... | Authors: | Wang, R, Natarajan, K, Robinson, H, Margulies, D.H. | Deposit date: | 2008-08-15 | Release date: | 2009-08-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Different vaccine vectors delivering the same antigen elicit CD8+ T cell responses with distinct clonotype and epitope specificity J.Immunol., 183, 2009
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3ECB
| Crystal structure of mouse H-2Dd in complex with peptide P18-I10 derived from human immunodeficiency virus envelope glycoprotein 120 | Descriptor: | 1,2-ETHANEDIOL, Beta-2 microglobulin, H-2 class I histocompatibility antigen, ... | Authors: | Natarajan, K, Wang, R, Margulies, D.H. | Deposit date: | 2008-08-29 | Release date: | 2009-07-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.698 Å) | Cite: | Structural basis of the CD8alphabeta/MHC class i interaction: focused recognition orients CD8beta to a T cell proximal position J.Immunol., 183, 2009
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2O5N
| Crystal structure of a Viral Glycoprotein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MuHV1gpm153, ... | Authors: | Mans, J, Natarajan, K, Robinson, H, Margulies, D.H. | Deposit date: | 2006-12-06 | Release date: | 2007-09-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Cellular Expression and Crystal Structure of the Murine Cytomegalovirus Major Histocompatibility Complex Class I-like Glycoprotein, m153. J.Biol.Chem., 282, 2007
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3DMM
| Crystal structure of the CD8 alpha beta/H-2Dd complex | Descriptor: | Beta-2 microglobulin, H-2 class I histocompatibility antigen, D-D alpha chain, ... | Authors: | Wang, R, Natarajan, K, Margulies, D.H. | Deposit date: | 2008-07-01 | Release date: | 2009-07-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis of the CD8alphabeta/MHC class i interaction: focused recognition orients CD8beta to a T cell proximal position. J.Immunol., 183, 2009
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3E6H
| MHC CLASS I H-2Dd heavy chain complexed with Beta-2 Microglobulin and a variant peptide, PI10, from the human immunodeficiency virus (BaL) envelope glycoprotein 120 | Descriptor: | Envelope glycoprotein 10-residue peptide, H-2 class I histocompatibility antigen, D-D alpha chain, ... | Authors: | Wang, R, Natarajan, K, Robinson, H, Margulies, D.H. | Deposit date: | 2008-08-15 | Release date: | 2009-08-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Different vaccine vectors delivering the same antigen elicit CD8+ T cell responses with distinct clonotype and epitope specificity J.Immunol., 183, 2009
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2MIZ
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3V52
| Structure of a monoclonal antibody complexed with its MHC-I antigen | Descriptor: | 1,2-ETHANEDIOL, ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, ... | Authors: | Mage, M.G, Dolan, M.A, Wang, R, Boyd, L.F, Revilleza, M.J, Robinson, H, Natarajan, K, Myers, N.B, Hansen, T.H, Margulies, D.H. | Deposit date: | 2011-12-15 | Release date: | 2012-07-25 | Last modified: | 2012-08-01 | Method: | X-RAY DIFFRACTION (1.697 Å) | Cite: | The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics. J.Immunol., 189, 2012
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7MFV
| Crystal structure of synthetic nanobody (Sb16) | Descriptor: | 1,2-ETHANEDIOL, Synthetic Nanobody #16 (Sb16) | Authors: | Jiang, J, Ahmad, J, Natarajan, K, Boyd, L.F, Margulies, D.H. | Deposit date: | 2021-04-11 | Release date: | 2021-06-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction. J.Biol.Chem., 297, 2021
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7TUC
| Crystal structure of HLA-B*44:05 (T73C) with 9mer EEFGRAFSF | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | Authors: | Jiang, J, Natarajan, K, Kim, E, Boyd, L.F, Margulies, D.H. | Deposit date: | 2022-02-02 | Release date: | 2022-09-07 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation. Nat Commun, 13, 2022
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7TUG
| Crystal structure of Tapasin in complex with PaSta2-Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PaSta2 Fab heavy chain, PaSta2 Fab kappa light chain, ... | Authors: | Jiang, J, Natarajan, K, Taylor, D.K, Boyd, L.F, Margulies, D.H. | Deposit date: | 2022-02-02 | Release date: | 2022-09-07 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation. Nat Commun, 13, 2022
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7TUD
| Crystal structure of HLA-B*44:05 (T73C) with 6mer EEFGRC and dipeptide GL | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, EEFGRC peptide, ... | Authors: | Jiang, J, Natarajan, K, Kim, E, Boyd, L.F, Margulies, D.H. | Deposit date: | 2022-02-02 | Release date: | 2022-09-07 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation. Nat Commun, 13, 2022
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7TUE
| Crystal structure of Tapasin in complex with HLA-B*44:05 (T73C) | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B alpha chain, ... | Authors: | Jiang, J, Natarajan, K, Kim, E, Boyd, L.F, Margulies, D.H. | Deposit date: | 2022-02-02 | Release date: | 2022-09-07 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation. Nat Commun, 13, 2022
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7TUF
| Crystal structure of Tapasin in complex with PaSta1-Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PaSta1 Fab heavy chain, PaSta1 Fab kappa light chain, ... | Authors: | Jiang, J, Natarajan, K, Taylor, D.K, Boyd, L.F, Margulies, D.H. | Deposit date: | 2022-02-02 | Release date: | 2022-09-07 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation. Nat Commun, 13, 2022
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