7KGK

Crystal structure of synthetic nanobody (Sb16) complexes with SARS-CoV-2 receptor binding domain

Summary for 7KGK

• Entry DOI: 10.2210/pdb7kgk/pdb
• Related: 7KGJ 7KGL 7KLW
• Descriptor: Spike protein S1, Sb16, Sybody-16, Synthetic Nanobody (2 entities in total)
• Functional Keywords: sars-cov-2, spike protein, rbd, antibody, nanobody, sybody, viral protein, epitope, neutralization
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 2
• Total formula weight: 35032.33

Authors

Jiang, J.,Ahmad, J.,Natarajan, K.,Boyd, L.F.,Margulies, D.H. (deposition date: 2020-10-16, release date: 2021-02-03, Last modification date: 2023-10-18)

• Primary citation: Ahmad, J.,Jiang, J.,Boyd, L.F.,Zeher, A.,Huang, R.,Xia, D.,Natarajan, K.,Margulies, D.H.; Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction.; J.Biol.Chem., 297:101202-101202, 2021; PubMed: 34537245; DOI: 10.1016/j.jbc.2021.101202

Experimental method

X-RAY DIFFRACTION (2.6 Å)