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3DMM

Crystal structure of the CD8 alpha beta/H-2Dd complex

Summary for 3DMM
Entry DOI10.2210/pdb3dmm/pdb
DescriptorH-2 class I histocompatibility antigen, D-D alpha chain, Beta-2 microglobulin, Synthetic peptide, ... (6 entities in total)
Functional Keywordst cell co-receptor cd8ab mhc complex, glycoprotein, immune response, membrane, mhc i, phosphoprotein, transmembrane, immunoglobulin domain, secreted, envelope protein, alternative splicing, polymorphism, immune system
Biological sourceMus musculus
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Cellular locationMembrane; Single-pass type I membrane protein: P01900 P10300
Cell membrane ; Single-pass type I membrane protein : P01731
Total number of polymer chains5
Total formula weight80119.84
Authors
Wang, R.,Natarajan, K.,Margulies, D.H. (deposition date: 2008-07-01, release date: 2009-07-14, Last modification date: 2023-08-30)
Primary citationWang, R.,Natarajan, K.,Margulies, D.H.
Structural basis of the CD8alphabeta/MHC class i interaction: focused recognition orients CD8beta to a T cell proximal position.
J.Immunol., 183:2554-2564, 2009
Cited by
PubMed: 19625641
DOI: 10.4049/jimmunol.0901276
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

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