7KLW

Crystal structure of synthetic nanobody (Sb45+Sb68) complexes with SARS-CoV-2 receptor binding domain

Summary for 7KLW

Entry DOI	10.2210/pdb7klw/pdb
Related	7KGJ 7KGK 7KGL
Descriptor	Spike protein S1, SB45, Synthetic Nanobody, SB68, Synthetic nanobody, ... (4 entities in total)
Functional Keywords	sars-cov-2, spike protein, receptor binding domain, rbd, antibody, nanobody, sybody, complex, neutralization, viral protein, epitope
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More
Total number of polymer chains	3
Total formula weight	48982.46
Authors	Jiang, J.,Ahmad, J.,Natarajan, K.,Boyd, L.F.,Margulies, D.H. (deposition date: 2020-11-01, release date: 2021-02-03, Last modification date: 2023-10-18)
Primary citation	Ahmad, J.,Jiang, J.,Boyd, L.F.,Zeher, A.,Huang, R.,Xia, D.,Natarajan, K.,Margulies, D.H. Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction. J.Biol.Chem., 297:101202-101202, 2021 Cited by PubMed: 34537245 DOI: 10.1016/j.jbc.2021.101202 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation