8TQ7

Crystal structure of Fab.34.2.12 in complex with MHC-I (H2-Dd)

Summary for 8TQ7

• Entry DOI: 10.2210/pdb8tq7/pdb
• Related: 8TQ4 8TQ5 8TQ6 8TQ8 8TQ9 8TQA
• Descriptor: H-2 class I histocompatibility antigen, D-D alpha chain, Beta-2-microglobulin, Transmembrane protein gp41, ... (8 entities in total)
• Functional Keywords: histocompatibility complex class i, mhc-i, immune response, immune system fab, antibody, anti-mhc antibody, cancer tumor, immune system
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 10
• Total formula weight: 182199.11

Authors

Jiang, J.,Boyd, L.F.,Natarajan, K.,Margulies, D.H. (deposition date: 2023-08-06, release date: 2024-03-20, Last modification date: 2024-04-10)

• Primary citation: Boyd, L.F.,Jiang, J.,Ahmad, J.,Natarajan, K.,Margulies, D.H.; Experimental Structures of Antibody/MHC-I Complexes Reveal Details of Epitopes Overlooked by Computational Prediction.; J Immunol., 212:1366-1380, 2024; PubMed: 38456672; DOI: 10.4049/jimmunol.2300839

Experimental method

X-RAY DIFFRACTION (2.8 Å)