8TQA
Crystal structure of Fab.28.14.8 in complex with MHC-I (H2-Db)
Summary for 8TQA
Entry DOI | 10.2210/pdb8tqa/pdb |
Related | 8TQ4 8TQ5 8TQ6 8TQ7 8TQ8 8TQ9 |
Descriptor | H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, Fab.28.14S Heavy chain, ... (9 entities in total) |
Functional Keywords | histocompatibility complex class i, mhc-i, immune response, immune system fab, antibody, anti-mhc antibody, cancer tumor, immune system |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 5 |
Total formula weight | 92570.07 |
Authors | Jiang, J.,Boyd, L.F.,Natarajan, K.,Margulies, D.H. (deposition date: 2023-08-06, release date: 2024-03-20, Last modification date: 2024-04-10) |
Primary citation | Boyd, L.F.,Jiang, J.,Ahmad, J.,Natarajan, K.,Margulies, D.H. Experimental Structures of Antibody/MHC-I Complexes Reveal Details of Epitopes Overlooked by Computational Prediction. J Immunol., 212:1366-1380, 2024 Cited by PubMed: 38456672DOI: 10.4049/jimmunol.2300839 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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