3P54
| Crystal Structure of the Japanese Encephalitis Virus Envelope Protein, strain SA-14-14-2. | Descriptor: | envelope glycoprotein | Authors: | Luca, V.C, Nelson, C.A, AbiMansour, J.P, Diamond, M.S, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2010-10-07 | Release date: | 2010-12-08 | Last modified: | 2012-02-08 | Method: | X-RAY DIFFRACTION (2.097 Å) | Cite: | Crystal structure of the Japanese encephalitis virus envelope protein. J.Virol., 86, 2012
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4FG0
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4XL1
| Complex of Notch1 (EGF11-13) bound to Delta-like 4 (N-EGF1) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Luca, V.C, Jude, K.M, Garcia, K.C. | Deposit date: | 2015-01-13 | Release date: | 2015-03-04 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural biology. Structural basis for Notch1 engagement of Delta-like 4. Science, 347, 2015
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4XLW
| Complex of Notch1 (EGF11-13) bound to Delta-like 4 (N-EGF2) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Delta-like protein, ... | Authors: | Luca, V.C, Jude, K.M, Garcia, K.C. | Deposit date: | 2015-01-13 | Release date: | 2015-03-04 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.39 Å) | Cite: | Structural biology. Structural basis for Notch1 engagement of Delta-like 4. Science, 347, 2015
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5UK5
| Complex of Notch1(EGF8-12) bound to Jagged1(N-EGF3) | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Garcia, K.C, Luca, V.C. | Deposit date: | 2017-01-19 | Release date: | 2017-03-08 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.506 Å) | Cite: | Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity. Science, 355, 2017
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8EGX
| Complex of Fat4(EC1-4) bound to Dchs1(EC1-4) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Medina, E, Luca, V.C. | Deposit date: | 2022-09-13 | Release date: | 2023-02-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.688 Å) | Cite: | Structure of the planar cell polarity cadherins Fat4 and Dachsous1. Nat Commun, 14, 2023
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8EGW
| Complex of Fat4(EC1-4) bound to Dchs1(EC1-3) | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Medina, E, Luca, V.C. | Deposit date: | 2022-09-13 | Release date: | 2023-02-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the planar cell polarity cadherins Fat4 and Dachsous1. Nat Commun, 14, 2023
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7TZ2
| Structure of human Fibrinogen-like protein 1 | Descriptor: | CALCIUM ION, Fibrinogen-like protein 1 | Authors: | Ming, Q, Tran, T.H, Luca, V.C. | Deposit date: | 2022-02-15 | Release date: | 2022-05-11 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition. Nat.Immunol., 23, 2022
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7TZG
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7TZH
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7TZE
| Structure of murine LAG3 domains 1-2 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte activation gene 3 protein | Authors: | Ming, Q, Tran, T.H, Luca, V.C. | Deposit date: | 2022-02-15 | Release date: | 2022-05-11 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition. Nat.Immunol., 23, 2022
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6XLQ
| Crystal Structure of the Human BTN3A1 Ectodomain in Complex with the CTX-2026 Fab | Descriptor: | Butyrophilin subfamily 3 member A1, CTX-2026 Heavy Chain, CTX-2026 Light Chain | Authors: | Payne, K.K, Mine, J.A, Biswas, S, Chaurio, R.A, Perales-Puchalt, A, Anadon, C.M, Costich, T.L, Harro, C.M, Walrath, J, Ming, Q, Tcyganov, E, Buras, A.L, Rigolizzo, K.E, Mandal, G, Lajoie, J, Ophir, M, Tchou, J, Marchion, D, Luca, V.C, Bobrowicz, P, McLaughlin, B, Eskiocak, U, Schmidt, M, Cubillos-Ruiz, J.R, Rodriguez, P.C, Gabrilovich, D.I, Conejo-Garcia, J.R. | Deposit date: | 2020-06-29 | Release date: | 2020-09-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | BTN3A1 governs antitumor responses by coordinating alpha beta and gamma delta T cells. Science, 369, 2020
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9CYL
| Structure of LAG3 loop1 deletion bound to the MHC class II molecule I-A(b) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Class-II-associated invariant chain peptide, H-2 class II histocompatibility antigen, ... | Authors: | Ming, Q, Tran, T.H, Antfolk, D, Luca, V.C. | Deposit date: | 2024-08-02 | Release date: | 2024-08-21 | Last modified: | 2024-09-25 | Method: | X-RAY DIFFRACTION (4.66 Å) | Cite: | Structural basis for mouse LAG3 interactions with the MHC class II molecule I-A b. Nat Commun, 15, 2024
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9CYM
| Structure of LAG3 bound to the MHC class II molecule I-A(b) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Class-II-associated invariant chain peptide, H-2 class II histocompatibility antigen, ... | Authors: | Ming, Q, Antfolk, D, Tran, T.H, Luca, V.C. | Deposit date: | 2024-08-02 | Release date: | 2024-08-21 | Last modified: | 2024-09-25 | Method: | X-RAY DIFFRACTION (3.84 Å) | Cite: | Structural basis for mouse LAG3 interactions with the MHC class II molecule I-A b. Nat Commun, 15, 2024
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4YQX
| Mouse IL-2 Bound to JES6-1 scFv Fragment | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-2, JES6-1 VH domain, ... | Authors: | Spangler, J.B, Luca, V.C, Jude, K.M, Garcia, K.C. | Deposit date: | 2015-03-13 | Release date: | 2015-07-01 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.826 Å) | Cite: | Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms. Immunity, 42, 2015
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7CFM
| Cryo-EM structure of the P395-bound GPBAR-Gs complex | Descriptor: | 2-(ethylamino)-6-[3-(4-propan-2-ylphenyl)propanoyl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-4-carboxamide, CHOLESTEROL, G-protein coupled bile acid receptor 1, ... | Authors: | Yang, F, Mao, C, Guo, L, Lin, J, Ming, Q, Xiao, P, Wu, X, Shen, Q, Guo, S, Shen, D, Lu, R, Zhang, L, Huang, S, Ping, Y, Zhang, C, Ma, C, Zhang, K, Liang, X, Shen, Y, Nan, F, Yi, F, Luca, V, Zhou, J, Jiang, C, Sun, J, Xie, X, Yu, X, Zhang, Y. | Deposit date: | 2020-06-27 | Release date: | 2020-09-09 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of GPBAR activation and bile acid recognition. Nature, 587, 2020
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7CFN
| Cryo-EM structure of the INT-777-bound GPBAR-Gs complex | Descriptor: | (2S,4R)-4-[(3R,5S,6R,7R,8R,9S,10S,12S,13R,14S,17R)-6-ethyl-10,13-dimethyl-3,7,12-tris(oxidanyl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-pentanoic acid, CHOLESTEROL, G-protein coupled bile acid receptor 1, ... | Authors: | Yang, F, Mao, C, Guo, L, Lin, J, Ming, Q, Xiao, P, Wu, X, Shen, Q, Guo, S, Shen, D, Lu, R, Zhang, L, Huang, S, Ping, Y, Zhang, C, Ma, C, Zhang, K, Liang, X, Shen, Y, Nan, F, Yi, F, Luca, V, Zhou, J, Jiang, C, Sun, J, Xie, X, Yu, X, Zhang, Y. | Deposit date: | 2020-06-27 | Release date: | 2020-09-09 | Last modified: | 2021-04-07 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of GPBAR activation and bile acid recognition. Nature, 587, 2020
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4YUE
| Mouse IL-2 Bound to S4B6 Fab Fragment | Descriptor: | GLYCEROL, Interleukin-2, S4B6 Fab heavy chain, ... | Authors: | Spangler, J.B, Jude, K.M, Garcia, K.C. | Deposit date: | 2015-03-18 | Release date: | 2015-07-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.194 Å) | Cite: | Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms. Immunity, 42, 2015
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