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9CYM

Structure of LAG3 bound to the MHC class II molecule I-A(b)

Summary for 9CYM
Entry DOI10.2210/pdb9cym/pdb
DescriptorSecreted lymphocyte activation gene 3 protein, H-2 class II histocompatibility antigen, A-B alpha chain, Class-II-associated invariant chain peptide, ... (5 entities in total)
Functional Keywordslag3, mhc class ii, immune checkpoint, t cell, immune system
Biological sourceMus musculus (house mouse)
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Total number of polymer chains4
Total formula weight72936.03
Authors
Ming, Q.,Antfolk, D.,Tran, T.H.,Luca, V.C. (deposition date: 2024-08-02, release date: 2024-08-21)
Primary citationMing, Q.,Antfolk, D.,Tran, T.H.,Luca, V.C.
Structural basis for LAG3 interactions with MHC class II
To Be Published,
Experimental method
X-RAY DIFFRACTION (3.84 Å)
Structure validation

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PDB entries from 2024-08-21

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