9CYL

Structure of LAG3 loop1 deletion bound to the MHC class II molecule I-A(b)

Summary for 9CYL

• Entry DOI: 10.2210/pdb9cyl/pdb
• Descriptor: H-2 class II histocompatibility antigen, A-B alpha chain, H-2 class II histocompatibility antigen, A beta chain, Class-II-associated invariant chain peptide, ... (5 entities in total)
• Functional Keywords: lag3, immune checkpoint, t cell, complex, mhcii, immune therapy, immune system
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 4
• Total formula weight: 70546.29

Authors

Ming, Q.,Tran, T.H.,Antfolk, D.,Luca, V.C. (deposition date: 2024-08-02, release date: 2024-08-21)

• Primary citation: Ming, Q.,Tran, T.H.,Antfolk, D.,Luca, V.C.; Structural basis for LAG3 interactions with MHC class II; To Be Published,

Experimental method

X-RAY DIFFRACTION (4.66 Å)