9CYL
Structure of LAG3 loop1 deletion bound to the MHC class II molecule I-A(b)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006955 | biological_process | immune response |
| A | 0016020 | cellular_component | membrane |
| A | 0019882 | biological_process | antigen processing and presentation |
| A | 0042613 | cellular_component | MHC class II protein complex |
| B | 0006955 | biological_process | immune response |
| B | 0016020 | cellular_component | membrane |
| B | 0019882 | biological_process | antigen processing and presentation |
| B | 0042613 | cellular_component | MHC class II protein complex |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCHVEH |
| Chain | Residue | Details |
| B | TYR198-HIS204 | |
| A | TYR188-HIS194 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 180 |
| Details | Domain: {"description":"Ig-like C1-type"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 93 |
| Details | Region: {"description":"Alpha-2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"12589760","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 93 |
| Details | Region: {"description":"Beta-2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 81 |
| Details | Domain: {"description":"Ig-like C2-type 1","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"35761082","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39209860","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7TZE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9CYL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9CYM","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"35761082","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38483996","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39209860","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7TZE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8DGG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9CYL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9CYM","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
