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5E69
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BU of 5e69 by Molmil
Glucocorticoid receptor DNA binding domain - IL8 NF-kB response element complex
Descriptor: DNA (5'-D(*AP*TP*CP*GP*TP*GP*GP*AP*AP*TP*TP*TP*CP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*GP*AP*AP*AP*TP*TP*CP*CP*AP*CP*GP*AP*T)-3'), Glucocorticoid receptor, ...
Authors:Hudson, W.H, Rye, E.A, Herbst, A.G, Ortlund, E.A.
Deposit date:2015-10-09
Release date:2017-02-08
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Cryptic glucocorticoid receptor-binding sites pervade genomic NF-kappa B response elements.
Nat Commun, 9, 2018
5E6D
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BU of 5e6d by Molmil
Glucocorticoid receptor DNA binding domain - ICAM1 NF-kB response element complex
Descriptor: DNA (5'-D(*GP*CP*TP*CP*CP*GP*GP*AP*AP*TP*TP*TP*CP*CP*AP*A)-3'), DNA (5'-D(*TP*TP*GP*GP*AP*AP*AP*TP*TP*CP*CP*GP*GP*AP*GP*C)-3'), Glucocorticoid receptor, ...
Authors:Hudson, W.H, Rye, E.A, Herbst, A.G, Ortlund, E.A.
Deposit date:2015-10-09
Release date:2017-02-08
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Cryptic glucocorticoid receptor-binding sites pervade genomic NF-kappa B response elements.
Nat Commun, 9, 2018
5IMX
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BU of 5imx by Molmil
Anaplastic lymphoma kinase (ALK) catalytic domain complexed with novel inhibitor 3-sulfonylpyrazol-4-amino pyrimidine
Descriptor: 5-chloro-N~2~-{5-methyl-4-(1-methylpiperidin-4-yl)-2-[(propan-2-yl)oxy]phenyl}-N~4~-{1-methyl-3-[(propan-2-yl)sulfonyl]-1H-pyrazol-4-yl}pyrimidine-2,4-diamine, ALK tyrosine kinase receptor
Authors:Wang, C, Zhang, P, Dong, J.
Deposit date:2016-03-07
Release date:2016-05-04
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Design and synthesis of novel 3-sulfonylpyrazol-4-amino pyrimidines as potent anaplastic lymphoma kinase (ALK) inhibitors.
Bioorg.Med.Chem.Lett., 26, 2016
8J69
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BU of 8j69 by Molmil
Crystal structure of HORMA domain-containing protein 1 (HORMAD1) from Homo sapiens
Descriptor: HORMA domain-containing protein 1
Authors:Yang, X.Y, Liu, X.H.
Deposit date:2023-04-25
Release date:2023-09-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Structural and biochemical insights into the interaction mechanism underlying HORMAD1 and its partner proteins.
Structure, 31, 2023
4MPZ
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BU of 4mpz by Molmil
Crystal structure of TCP10c domain of Drosophila melanogaster Sas-4
Descriptor: IMIDAZOLE, Sas-4
Authors:Li, H, Zheng, X.
Deposit date:2013-09-14
Release date:2014-01-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:The conserved TCP domain of Sas-4/CPAP is essential for Peri-centriolar material tethering during centrosome biogenesis
Proc.Natl.Acad.Sci.USA, 2014
5UV5
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BU of 5uv5 by Molmil
Crystal Structure of a 2-Hydroxyisoquinoline-1,3-dione RNase H Active Site Inhibitor with Multiple Binding Modes to HIV Reverse Transcriptase
Descriptor: 7-(furan-2-yl)-2-hydroxyisoquinoline-1,3(2H,4H)-dione, MANGANESE (II) ION, Reverse transcriptase/ribonuclease H, ...
Authors:Kirby, K.A, Sarafianos, S.G.
Deposit date:2017-02-19
Release date:2017-08-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:A 2-Hydroxyisoquinoline-1,3-Dione Active-Site RNase H Inhibitor Binds in Multiple Modes to HIV-1 Reverse Transcriptase.
Antimicrob. Agents Chemother., 61, 2017
5ZZ9
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BU of 5zz9 by Molmil
Crystal structure of Homer2 EVH1/Drebrin PPXXF complex
Descriptor: Homer protein homolog 2, Peptide from Drebrin
Authors:Li, Z, Liu, H, Li, J, Liu, W, Zhang, M.
Deposit date:2018-05-31
Release date:2018-12-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Homer Tetramer Promotes Actin Bundling Activity of Drebrin.
Structure, 27, 2019
8GT9
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BU of 8gt9 by Molmil
Selective targeting of the Beclin 2-Atg14L coiled coil complex by stapled peptides promotes autophagy and endolysosomal trafficking of GPCRs
Descriptor: Beclin-2
Authors:Qiu, X, Zhao, Y.
Deposit date:2022-09-07
Release date:2023-07-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:The potent BECN2-ATG14 coiled-coil interaction is selectively critical for endolysosomal degradation of GPRASP1/GASP1-associated GPCRs.
Autophagy, 19, 2023
8GU7
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BU of 8gu7 by Molmil
Selective targeting of the Beclin 2-Atg14L coiled coil complex by stapled peptides promotes autophagy and endolysosomal trafficking of GPCRs
Descriptor: Beclin 1-associated autophagy-related key regulator, Beclin-2
Authors:Qiu, X, Zhao, Y.
Deposit date:2022-09-11
Release date:2023-07-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The potent BECN2-ATG14 coiled-coil interaction is selectively critical for endolysosomal degradation of GPRASP1/GASP1-associated GPCRs.
Autophagy, 19, 2023
7VXH
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BU of 7vxh by Molmil
Coxsackievirus B3 full particle at pH7.4 (VP3-234Q)
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Wang, Q.L, Liu, C.C.
Deposit date:2021-11-12
Release date:2022-01-19
Last modified:2022-08-03
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VY0
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BU of 7vy0 by Molmil
Coxsackievirus B3 full particle at pH7.4 (VP3-234N)
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Wang, Q.L, Liu, C.C.
Deposit date:2021-11-13
Release date:2022-01-19
Last modified:2022-08-03
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VYM
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BU of 7vym by Molmil
Coxsackievirus B3 at pH7.4 (VP3-234E) incubation with coxsackievirus and adenovirus receptor for 10min
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Wang, Q.L, Liu, C.C.
Deposit date:2021-11-14
Release date:2022-01-19
Last modified:2022-08-10
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VY5
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BU of 7vy5 by Molmil
Coxsackievirus B3 (VP3-234Q) incubation with CD55 at pH7.4
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Wang, Q.L, Liu, C.C.
Deposit date:2021-11-13
Release date:2022-01-19
Last modified:2022-08-10
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VY6
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BU of 7vy6 by Molmil
Coxsackievirus B3(VP3-234N) incubate with CD55 at pH7.4
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Wang, Q.L, Liu, C.C.
Deposit date:2021-11-13
Release date:2022-01-19
Last modified:2022-08-10
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VXZ
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BU of 7vxz by Molmil
Coxsackievirus B3 at pH7.4 (VP3-234Q) incubation with coxsackievirus and adenovirus receptor for 20min
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Wang, Q.L, Liu, C.C.
Deposit date:2021-11-13
Release date:2022-01-19
Last modified:2022-08-03
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VYL
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BU of 7vyl by Molmil
Coxsackievirus B3 at pH5.5 (VP3-234Q) incubation with coxsackievirus and adenovirus receptor for 20min
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Wang, Q.L, Liu, C.C.
Deposit date:2021-11-14
Release date:2022-01-19
Last modified:2022-08-10
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VYK
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BU of 7vyk by Molmil
Coxsackievirus B3 at pH7.4 (VP3-234Q) incubation with coxsackievirus and adenovirus receptor for 10min
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Wang, Q.L, Liu, C.C.
Deposit date:2021-11-14
Release date:2022-01-19
Last modified:2022-08-10
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7W17
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BU of 7w17 by Molmil
Coxsackievirus B3 full particle at pH7.4 (VP3-234E)
Descriptor: PALMITIC ACID, VP1, VP2, ...
Authors:Wang, Q.L, Liu, C.C.
Deposit date:2021-11-19
Release date:2022-01-19
Last modified:2022-08-10
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7W14
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BU of 7w14 by Molmil
Coxsackievirus B3 at pH7.4 (VP3-234E) incubation with coxsackievirus and adenovirus receptor for 20min
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Wang, Q.L, Liu, C.C.
Deposit date:2021-11-19
Release date:2022-01-19
Last modified:2022-08-03
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7YJI
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BU of 7yji by Molmil
Crystal structure of Lpg1083 from Legionella pneumophila
Descriptor: ACETATE ION, T4SS effector Lpg1083
Authors:Ge, H, Gao, J, Chen, X.
Deposit date:2022-07-20
Release date:2023-06-28
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The bacterial effector SidN/Lpg1083 promotes cell death by targeting Lamin-B2.
J Mol Cell Biol, 15, 2023
8JJ9
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BU of 8jj9 by Molmil
Human FAM91A1 N terminal domain in complex with TBC1D23
Descriptor: Protein FAM91A1, TBC1 domain family member 23
Authors:Deng, H.Q, Zhang, S.T, Jia, D.
Deposit date:2023-05-29
Release date:2024-04-24
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:FAM91A1-TBC1D23 complex structure reveals human genetic variations susceptible for PCH.
Proc.Natl.Acad.Sci.USA, 120, 2023
7X86
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BU of 7x86 by Molmil
The crystal structure of PloI4-F124L in complex with endo-4+2 adduct
Descriptor: (4S,4aS,6aR,8R,9R,10aS,13S,14aS,18aR,18bR,E)-9-ethyl-4,8,19-trihydroxy-10a,12,13,18a-tetramethyl-2,3,4,4a,6a,7,8,9,10,10a,13,14,18a,18b-tetradecahydro-14a,17-(metheno)benzo[b]naphtho[2,1-h][1]azacyclododecine-16,18(1H,15H)-dione, PloI4
Authors:Li, M, Pan, L.F.
Deposit date:2022-03-11
Release date:2023-02-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.303 Å)
Cite:A cyclase that catalyses competing 2 + 2 and 4 + 2 cycloadditions.
Nat.Chem., 15, 2023
7X80
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BU of 7x80 by Molmil
The crystal structure of PloI4-C16M/D46A/I137V
Descriptor: GLYCEROL, PloI4
Authors:Li, M, Pan, L.F.
Deposit date:2022-03-10
Release date:2023-02-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:A cyclase that catalyses competing 2 + 2 and 4 + 2 cycloadditions.
Nat.Chem., 15, 2023
7X7Z
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BU of 7x7z by Molmil
The crystal structure of 2+2/4+2 cyclase PloI4
Descriptor: PloI4
Authors:Li, M, Pan, L.F.
Deposit date:2022-03-10
Release date:2023-02-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.903 Å)
Cite:A cyclase that catalyses competing 2 + 2 and 4 + 2 cycloadditions.
Nat.Chem., 15, 2023
7X81
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BU of 7x81 by Molmil
The crystal structure of PloI4-C16M/D46A/I137V in complex with exo-2+2 adduct
Descriptor: (4S,4aS,6aR,8R,9R,11E,12aR,14aS,17E,18aR,18bR)-9-ethyl-4,8,19-trihydroxy-11,12a,13,18a-tetramethyl-2,3,4,4a,6a,7,8,9,10,12a,13,14,18a,18b-tetradecahydro-14a,17-(metheno)cyclobuta[b]naphtho[2,1-j][1]azacyclotetradecine-16,18(1H,15H)-dione, PloI4
Authors:Li, M, Pan, L.F.
Deposit date:2022-03-10
Release date:2023-02-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.104 Å)
Cite:A cyclase that catalyses competing 2 + 2 and 4 + 2 cycloadditions.
Nat.Chem., 15, 2023

221051

數據於2024-06-12公開中

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