5GUF

Structural insight into an intramembrane enzyme for archaeal membrane lipids biosynthesis

Summary for 5GUF

Entry DOI	10.2210/pdb5guf/pdb
Descriptor	CDP-archaeol synthase, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	membrane protein, cars, transferase
Biological source	Aeropyrum pernix K1
Cellular location	Cell membrane ; Multi-pass membrane protein : Q9YF05
Total number of polymer chains	1
Total formula weight	19635.59
Authors	Cheng, W.,Ren, S. (deposition date: 2016-08-29, release date: 2017-10-11, Last modification date: 2024-03-20)
Primary citation	Ren, S.,Caforio, A.,Yang, Q.,Sun, B.,Yu, F.,Zhu, X.,Wang, J.,Dou, C.,Fu, Q.,Huang, N.,Sun, Q.,Nie, C.,Qi, S.,Gong, X.,He, J.,Wei, Y.,Driessen, A.J.,Cheng, W. Structural and mechanistic insights into the biosynthesis of CDP-archaeol in membranes. Cell Res., 27:1378-1391, 2017 Cited by PubMed: 28961231 DOI: 10.1038/cr.2017.122 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.397 Å)

Structure validation