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5L21
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BU of 5l21 by Molmil
Crystal structure of BoNT/A receptor binding domain in complex with VHH C2
Descriptor: Botulinum neurotoxin type A, VHH-C2
Authors:Yao, G, Jin, R.
Deposit date:2016-07-29
Release date:2017-08-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:A camelid single-domain antibody neutralizes botulinum neurotoxin A by blocking host receptor binding.
Sci Rep, 7, 2017
5LR0
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BU of 5lr0 by Molmil
Binding domain of Botulinum Neurotoxin DC in complex with SialylT
Descriptor: Botulinum neurotoxin D/C protein, N-acetyl-alpha-neuraminic acid, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, ...
Authors:Berntsson, R.P.-A, Stenmark, P.
Deposit date:2016-08-18
Release date:2017-08-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structural basis for the unique ganglioside and cell membrane recognition mechanism of botulinum neurotoxin DC.
Nat Commun, 8, 2017
6RIM
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BU of 6rim by Molmil
Crystal structure of the catalytic domain of the Weissela oryzae botulinum like toxin
Descriptor: CALCIUM ION, Putative botulinum-like toxin Wo, ZINC ION
Authors:Kosenina, S, Masuyer, G, Stenmark, P.
Deposit date:2019-04-24
Release date:2019-05-29
Last modified:2019-08-21
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the catalytic domain of the Weissella oryzae botulinum-like toxin.
Febs Lett., 593, 2019
8BDP
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BU of 8bdp by Molmil
A GH20 family sulfoglycosidase Bt4394 in complex with NAG-thiazoline and sulfite
Descriptor: Beta-N-acetylhexosaminidase, CHLORIDE ION
Authors:Zhang, Z, He, Y, Jin, Y.
Deposit date:2022-10-19
Release date:2023-01-11
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Mechanistic and Structural Insights into the Specificity and Biological Functions of Bacterial Sulfoglycosidases
Acs Catalysis, 2022
8C8G
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BU of 8c8g by Molmil
Cryo-EM structure of BoNT/Wo-NTNH complex
Descriptor: Putative botulinum-like toxin Wo, Structural protein
Authors:Kosenina, S, Skerlova, J, Stenmark, P.
Deposit date:2023-01-20
Release date:2023-10-04
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:The cryo-EM structure of the BoNT/Wo-NTNH complex reveals two immunoglobulin-like domains.
Febs J., 291, 2024
8CQ2
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BU of 8cq2 by Molmil
Photorhabdus luminescens TcdA1 prepore-to-pore intermediate, C16S, C20S, C870S, T1279C mutant
Descriptor: TcdA1
Authors:Nganga, P.N, Roderer, D, Belyy, A, Prumbaum, D, Raunser, S.
Deposit date:2023-03-03
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Kinetics of the syringe-like injection mechanism of Tc toxins
to be published
8CPZ
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BU of 8cpz by Molmil
Photorhabdus luminescens TcdA1 prepore-to-pore intermediate, K1179W mutant
Descriptor: TcdA1
Authors:Nganga, P.N, Roderer, D, Belyy, A, Prumbaum, D, Raunser, S.
Deposit date:2023-03-03
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Kinetics of the syringe-like injection mechanism of Tc toxins
to be published
8CQ0
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BU of 8cq0 by Molmil
Photorhabdus luminescens TcdA1 prepore-to-pore intermediate, K567W K2008W mutant
Descriptor: TcdA1
Authors:Nganga, P.N, Roderer, D, Belyy, A, Prumbaum, D, Raunser, S.
Deposit date:2023-03-03
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Kinetics of the syringe-like injection mechanism of Tc toxins
to be published
8QEO
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BU of 8qeo by Molmil
cryo-EM structure complex of Frizzled-7 and Clostridioides difficile toxin B
Descriptor: Frizzled-7, Toxin B, ZINC ION
Authors:Kinsolving, J, Bous, J.
Deposit date:2023-09-01
Release date:2024-03-20
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Structural and functional insight into the interaction of Clostridioides difficile toxin B and FZD 7.
Cell Rep, 43, 2024
8QEN
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BU of 8qen by Molmil
cryo-EM structure of apo Clostridioides difficile toxin B
Descriptor: Toxin B, ZINC ION
Authors:Kinsolving, J, Bous, J, Structural Genomics Consortium (SGC)
Deposit date:2023-09-01
Release date:2024-03-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural and functional insight into the interaction of Clostridioides difficile toxin B and FZD 7.
Cell Rep, 43, 2024
6ES1
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BU of 6es1 by Molmil
Crystal structure of the binding domain from botulinum neurotoxin A2 bound to extracellular domain of human receptor SV2C
Descriptor: ACETATE ION, Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2C
Authors:Gustafsson, R, Masuyer, G, Stenmark, P.
Deposit date:2017-10-19
Release date:2018-04-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Botulinum Neurotoxin A2 in Complex with the Human Protein Receptor SV2C Reveals Plasticity in Receptor Binding.
Toxins (Basel), 10, 2018
6LSR
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BU of 6lsr by Molmil
Cryo-EM structure of a pre-60S ribosomal subunit - state B
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N.
Deposit date:2020-01-20
Release date:2020-08-26
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Structural snapshots of human pre-60S ribosomal particles before and after nuclear export.
Nat Commun, 11, 2020
6LQM
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BU of 6lqm by Molmil
Cryo-EM structure of a pre-60S ribosomal subunit - state C
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N.
Deposit date:2020-01-14
Release date:2020-08-26
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Structural snapshots of human pre-60S ribosomal particles before and after nuclear export.
Nat Commun, 11, 2020
6LU8
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BU of 6lu8 by Molmil
Cryo-EM structure of a human pre-60S ribosomal subunit - state A
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N.
Deposit date:2020-01-26
Release date:2020-08-26
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Structural snapshots of human pre-60S ribosomal particles before and after nuclear export.
Nat Commun, 11, 2020
6LSS
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BU of 6lss by Molmil
Cryo-EM structure of a pre-60S ribosomal subunit - state preA
Descriptor: 28S rRNA, 5S rRNA, 60S ribosomal protein L11, ...
Authors:Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N.
Deposit date:2020-01-20
Release date:2020-08-26
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Structural snapshots of human pre-60S ribosomal particles before and after nuclear export.
Nat Commun, 11, 2020
3U28
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BU of 3u28 by Molmil
Crystal structure of a Cbf5-Nop10-Gar1 complex from Saccharomyces cerevisiae
Descriptor: H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 3, H/ACA ribonucleoprotein complex subunit 4
Authors:Ye, K, Li, S.
Deposit date:2011-10-02
Release date:2011-12-14
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Reconstitution and structural analysis of the yeast box H/ACA RNA-guided pseudouridine synthase
Genes Dev., 25, 2011
5Z2C
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BU of 5z2c by Molmil
Crystal structure of ALPK-1 N-terminal domain in complex with ADP-heptose
Descriptor: Alpha-protein kinase 1, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4S,5S,6R)-6-[(1S)-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl] hydrogen phosphate
Authors:Ding, J, She, Y, Shao, F.
Deposit date:2018-01-02
Release date:2018-08-22
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.594 Å)
Cite:Alpha-kinase 1 is a cytosolic innate immune receptor for bacterial ADP-heptose.
Nature, 561, 2018
7ML7
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BU of 7ml7 by Molmil
Structural basis for CSPG4 as a receptor for TcdB and a therapeutic target in Clostridioides difficile infection
Descriptor: Chondroitin sulfate proteoglycan 4, Toxin B, ZINC ION
Authors:Chen, P, Jin, R.
Deposit date:2021-04-27
Release date:2021-06-09
Last modified:2021-06-30
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Structural basis for CSPG4 as a receptor for TcdB and a therapeutic target in Clostridioides difficile infection.
Nat Commun, 12, 2021
2NP0
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BU of 2np0 by Molmil
Crystal structure of the Botulinum neurotoxin type B complexed with synaptotagamin-II ectodomain
Descriptor: Botulinum neurotoxin type B, CALCIUM ION, CHLORIDE ION, ...
Authors:Chai, Q, Arndt, J.W, Stevens, R.C.
Deposit date:2006-10-26
Release date:2006-12-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structural basis of cell surface receptor recognition by botulinum neurotoxin B.
Nature, 444, 2006
8J6K
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BU of 8j6k by Molmil
Crystal structure of pro-interleukin-18 and caspase-4 complex
Descriptor: Arginine ADP-riboxanase OspC3, Caspase-4 subunit p10, Caspase-4 subunit p20, ...
Authors:Sun, Q, Hou, Y.J, Ding, J.
Deposit date:2023-04-26
Release date:2023-11-29
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Recognition and maturation of IL-18 by caspase-4 noncanonical inflammasome.
Nature, 624, 2023
7U1Z
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BU of 7u1z by Molmil
Crystal structure of the DRBD and CROPs of TcdA
Descriptor: SULFATE ION, Toxin A
Authors:Baohua, C, Peng, C, Kay, P, Rongsheng, J.
Deposit date:2022-02-22
Release date:2022-03-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:Structure and conformational dynamics of Clostridioides difficile toxin A.
Life Sci Alliance, 5, 2022
7UIB
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BU of 7uib by Molmil
Crystal structure of BoNT/E receptor binding domain in complex with SV2, VHH, and sialic acid
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-beta-neuraminic acid, ...
Authors:Liu, Z, Jin, R, Chen, P.
Deposit date:2022-03-29
Release date:2023-04-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2.
Nat Commun, 14, 2023
7UIA
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BU of 7uia by Molmil
Crystal structure of BoNT/E receptor binding domain in complex with SV2 and VHH
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
Authors:Liu, Z, Jin, R, Chen, P.
Deposit date:2022-03-28
Release date:2023-04-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2.
Nat Commun, 14, 2023
7UIE
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BU of 7uie by Molmil
Crystal structure of HcE-JLE-G6
Descriptor: Botulinum neurotoxin E heavy chain, JLE-G6
Authors:Jin, R, Lam, K.
Deposit date:2022-03-29
Release date:2023-04-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.23 Å)
Cite:Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2.
Nat Commun, 14, 2023
5G06
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BU of 5g06 by Molmil
Cryo-EM structure of yeast cytoplasmic exosome
Descriptor: EXOSOME COMPLEX COMPONENT CSL4, EXOSOME COMPLEX COMPONENT MTR3, EXOSOME COMPLEX COMPONENT RRP4, ...
Authors:Liu, J.J, Niu, C.Y, Wu, Y, Tan, D, Wang, Y, Ye, M.D, Liu, Y, Zhao, W.W, Zhou, K, Liu, Q.S, Dai, J.B, Yang, X.R, Dong, M.Q, Huang, N, Wang, H.W.
Deposit date:2016-03-17
Release date:2016-06-15
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Cryoem Structure of Yeast Cytoplasmic Exosome Complex.
Cell Res., 26, 2016

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數據於2024-07-24公開中

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