5JXH
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![BU of 5jxh by Molmil](/molmil-images/mine/5jxh) | Structure the proprotein convertase furin in complex with meta-guanidinomethyl-Phac-RVR-Amba at 2.0 Angstrom resolution. | Descriptor: | 2UC-ARG-VAL-ARG-00S, CALCIUM ION, CHLORIDE ION, ... | Authors: | Dahms, S.O, Arciniega, M, Steinmetzer, T, Huber, R, Than, M.E. | Deposit date: | 2016-05-13 | Release date: | 2016-10-05 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the unliganded form of the proprotein convertase furin suggests activation by a substrate-induced mechanism. Proc.Natl.Acad.Sci.USA, 113, 2016
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5JXI
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![BU of 5jxi by Molmil](/molmil-images/mine/5jxi) | Structure of the unliganded form of the proprotein convertase furin in presence of EDTA. | Descriptor: | CALCIUM ION, CHLORIDE ION, Furin, ... | Authors: | Dahms, S.O, Arciniega, M, Steinmetzer, T, Huber, R, Than, M.E. | Deposit date: | 2016-05-13 | Release date: | 2016-10-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the unliganded form of the proprotein convertase furin suggests activation by a substrate-induced mechanism. Proc.Natl.Acad.Sci.USA, 113, 2016
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5JXG
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![BU of 5jxg by Molmil](/molmil-images/mine/5jxg) | Structure of the unliganded form of the proprotein convertase furin. | Descriptor: | CALCIUM ION, CHLORIDE ION, Furin, ... | Authors: | Dahms, S.O, Arciniega, M, Steinmetzer, T, Huber, R, Than, M.E. | Deposit date: | 2016-05-13 | Release date: | 2016-10-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of the unliganded form of the proprotein convertase furin suggests activation by a substrate-induced mechanism. Proc.Natl.Acad.Sci.USA, 113, 2016
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8OYH
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![BU of 8oyh by Molmil](/molmil-images/mine/8oyh) | X-ray structure of furin (PCSK3) in complex with Guanidinomethyl-Phac-Can-Tle-Can-6-(aminomethyl)-3-amino-isoindol | Descriptor: | CALCIUM ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | Authors: | Dahms, S.O, Brandstetter, H. | Deposit date: | 2023-05-04 | Release date: | 2024-03-13 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Fragment-Based Design, Synthesis, and Characterization of Aminoisoindole-Derived Furin Inhibitors. Chemmedchem, 19, 2024
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8B4W
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![BU of 8b4w by Molmil](/molmil-images/mine/8b4w) | X-ray structure of furin (PCSK3) in complex with 1H-isoindol-3-amine | Descriptor: | 1H-isoindol-3-amine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Dahms, S.O, Brandstetter, H. | Deposit date: | 2022-09-21 | Release date: | 2023-10-04 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Fragment-Based Design, Synthesis, and Characterization of Aminoisoindole-Derived Furin Inhibitors. Chemmedchem, 19, 2024
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8B4X
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![BU of 8b4x by Molmil](/molmil-images/mine/8b4x) | X-ray structure of furin (PCSK3) in complex with Guanidinomethyl-Phac-R-Tle-K-6-(aminomethyl)-3-amino-isoindol | Descriptor: | CALCIUM ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | Authors: | Dahms, S.O, Brandstetter, H. | Deposit date: | 2022-09-21 | Release date: | 2023-10-04 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Fragment-Based Design, Synthesis, and Characterization of Aminoisoindole-Derived Furin Inhibitors. Chemmedchem, 19, 2024
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8B4V
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![BU of 8b4v by Molmil](/molmil-images/mine/8b4v) | X-ray structure of furin (PCSK3) in complex with benzamidine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BENZAMIDINE, CALCIUM ION, ... | Authors: | Dahms, S.O, Brandstetter, H. | Deposit date: | 2022-09-21 | Release date: | 2023-10-04 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Fragment-Based Design, Synthesis, and Characterization of Aminoisoindole-Derived Furin Inhibitors. Chemmedchem, 19, 2024
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6YD7
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![BU of 6yd7 by Molmil](/molmil-images/mine/6yd7) | |
6YD4
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![BU of 6yd4 by Molmil](/molmil-images/mine/6yd4) | |
6YD3
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![BU of 6yd3 by Molmil](/molmil-images/mine/6yd3) | |
6YD2
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![BU of 6yd2 by Molmil](/molmil-images/mine/6yd2) | |
6HZC
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![BU of 6hzc by Molmil](/molmil-images/mine/6hzc) | |
6HZB
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![BU of 6hzb by Molmil](/molmil-images/mine/6hzb) | |
6HLD
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![BU of 6hld by Molmil](/molmil-images/mine/6hld) | |
6HLB
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![BU of 6hlb by Molmil](/molmil-images/mine/6hlb) | |
6HLE
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![BU of 6hle by Molmil](/molmil-images/mine/6hle) | |
6HZD
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![BU of 6hzd by Molmil](/molmil-images/mine/6hzd) | |
6HZA
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![BU of 6hza by Molmil](/molmil-images/mine/6hza) | |
4RYD
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![BU of 4ryd by Molmil](/molmil-images/mine/4ryd) | |
4LXC
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![BU of 4lxc by Molmil](/molmil-images/mine/4lxc) | The antimicrobial peptidase lysostaphin from Staphylococcus simulans | Descriptor: | Lysostaphin, SULFATE ION, ZINC ION | Authors: | Sabala, I, Jagielska, E, Bardelang, P.T, Czapinska, H, Dahms, S.O, Sharpe, J.A, James, R, Than, M.E, Thomas, N.R, Bochtler, M. | Deposit date: | 2013-07-29 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Crystal structure of the antimicrobial peptidase lysostaphin from Staphylococcus simulans. Febs J., 281, 2014
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3QO4
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![BU of 3qo4 by Molmil](/molmil-images/mine/3qo4) | The Crystal Structure of Death Receptor 6 | Descriptor: | ACETATE ION, SULFATE ION, Tumor necrosis factor receptor superfamily member 21 | Authors: | Kuester, M, Kemmerzehl, S, Dahms, S.O, Roeser, D, Than, M.E. | Deposit date: | 2011-02-09 | Release date: | 2011-05-18 | Last modified: | 2012-02-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The crystal structure of death receptor 6 (DR6): a potential receptor of the amyloid precursor protein (APP). J.Mol.Biol., 409, 2011
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4QPB
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![BU of 4qpb by Molmil](/molmil-images/mine/4qpb) | Catalytic domain of the antimicrobial peptidase lysostaphin from Staphylococcus simulans crystallized in the absence of phosphate | Descriptor: | 1,2-ETHANEDIOL, Lysostaphin, ZINC ION | Authors: | Sabala, I, Jagielska, E, Bardelang, P.T, Czapinska, H, Dahms, S.O, Sharpe, J.A, James, R, Than, M.E, Thomas, N.R, Bochtler, M. | Deposit date: | 2014-06-22 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Crystal structure of the antimicrobial peptidase lysostaphin from Staphylococcus simulans. Febs J., 281, 2014
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4QP5
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![BU of 4qp5 by Molmil](/molmil-images/mine/4qp5) | Catalytic domain of the antimicrobial peptidase lysostaphin from Staphylococcus simulans crystallized in the presence of phosphate | Descriptor: | GLYCEROL, Lysostaphin, PHOSPHATE ION, ... | Authors: | Sabala, I, Jagielska, E, Bardelang, P.T, Czapinska, H, Dahms, S.O, Sharpe, J.A, James, R, Than, M.E, Thomas, N.R, Bochtler, M. | Deposit date: | 2014-06-22 | Release date: | 2014-07-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.26 Å) | Cite: | Crystal structure of the antimicrobial peptidase lysostaphin from Staphylococcus simulans. Febs J., 281, 2014
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4PWQ
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![BU of 4pwq by Molmil](/molmil-images/mine/4pwq) | |
6FK0
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![BU of 6fk0 by Molmil](/molmil-images/mine/6fk0) | |