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4KNF
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BU of 4knf by Molmil
Crystal structure of a blue-light absorbing proteorhodopsin double-mutant D97N/Q105L from HOT75
Descriptor: Blue-light absorbing proteorhodopsin, RETINAL
Authors:Ran, T, Ozorowski, G, Gao, Y, Wang, W, Luecke, H.
Deposit date:2013-05-09
Release date:2013-06-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Cross-protomer interaction with the photoactive site in oligomeric proteorhodopsin complexes.
Acta Crystallogr.,Sect.D, 69, 2013
4KLY
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BU of 4kly by Molmil
Crystal structure of a blue-light absorbing proteorhodopsin mutant D97N from HOT75
Descriptor: Blue-light absorbing proteorhodopsin, RETINAL
Authors:Ran, T, Ozorowski, G, Gao, Y, Wang, W, Luecke, H.
Deposit date:2013-05-07
Release date:2013-06-05
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Cross-protomer interaction with the photoactive site in oligomeric proteorhodopsin complexes.
Acta Crystallogr.,Sect.D, 69, 2013
7V4Y
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BU of 7v4y by Molmil
TTHA1264/TTHA1265 complex
Descriptor: Putative zinc protease, ZINC ION, Zinc-dependent peptidase
Authors:Xu, M, Xu, Q, Ran, T, Wang, W, Sun, B, Wang, Q.
Deposit date:2021-08-16
Release date:2022-06-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of TTHA1265 and TTHA1264/TTHA1265 complex reveal an intrinsic heterodimeric assembly.
Int.J.Biol.Macromol., 207, 2022
4L4M
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BU of 4l4m by Molmil
Structural Analysis of a Phosphoribosylated Inhibitor in Complex with Human Nicotinamide Phosphoribosyltransferase
Descriptor: 1,2-ETHANEDIOL, N-{4-[(3,5-difluorophenyl)sulfonyl]benzyl}imidazo[1,2-a]pyridine-7-carboxamide, Nicotinamide phosphoribosyltransferase, ...
Authors:Oh, A, Ho, Y, Zak, M, Liu, Y, Yuen, P, Zheng, X, Dragovich, S.P, Wang, W.
Deposit date:2013-06-08
Release date:2014-06-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.445 Å)
Cite:Structural and biochemical analyses of the catalysis and potency impact of inhibitor phosphoribosylation by human nicotinamide phosphoribosyltransferase.
Chembiochem, 15, 2014
4GVE
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BU of 4gve by Molmil
Tacaribe nucleoprotein structure
Descriptor: MAGNESIUM ION, Nucleoprotein, ZINC ION
Authors:Jiang, X, Huang, Q, Wang, W, Dong, H, Ly, H, Liang, Y, Dong, C.
Deposit date:2012-08-30
Release date:2013-05-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
J.Biol.Chem., 288, 2013
4GV6
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BU of 4gv6 by Molmil
Structures of Lassa and Tacaribe viral nucleoproteins with or without 5 triphosphate dsRNA substrate reveal a unique 3 -5 exoribonuclease mechanism to suppress type I interferon production
Descriptor: MANGANESE (II) ION, Nucleoprotein, RNA (5'-R(*(GTP)P*GP*GP*C)-3'), ...
Authors:Jiang, X, Huang, Q, Wang, W, Dong, H, Ly, H, Liang, Y, Dong, C.
Deposit date:2012-08-30
Release date:2013-05-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
J.Biol.Chem., 288, 2013
4MIW
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BU of 4miw by Molmil
High-resolution structure of the N-terminal endonuclease domain of the Lassa virus L polymerase
Descriptor: MAGNESIUM ION, RNA-directed RNA polymerase L
Authors:Wallat, G.D, Huang, Q, Wang, W, Dong, H, Ly, H, Liang, Y, Dong, C.
Deposit date:2013-09-02
Release date:2014-03-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:High-resolution structure of the N-terminal endonuclease domain of the lassa virus L polymerase in complex with magnesium ions.
Plos One, 9, 2014
4GV3
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BU of 4gv3 by Molmil
Structures of Lassa and Tacaribe viral nucleoproteins with or without 5 triphosphate dsRNA substrate reveal a unique 3 -5 exoribonuclease mechanism to suppress type I interferon production
Descriptor: MANGANESE (II) ION, Nucleoprotein, RNA (5'-R(*(GTP)P*GP*GP*C)-3'), ...
Authors:Jiang, X, Huang, Q, Wang, W, Dong, H, Ly, H, Liang, Y, Dong, C.
Deposit date:2012-08-30
Release date:2013-05-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
J.Biol.Chem., 288, 2013
4G9Z
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BU of 4g9z by Molmil
Lassa nucleoprotein with dsRNA reveals novel mechanism for immune suppression
Descriptor: Nucleoprotein, RNA (5'-R(P*GP*CP*CP*C)-3'), RNA (5'-R(P*GP*GP*GP*C)-3'), ...
Authors:Jiang, X, Huang, Q, Wang, W, Dong, H, Ly, H, Liang, Y, Dong, C, Scottish Structural Proteomics Facility (SSPF)
Deposit date:2012-07-24
Release date:2013-04-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
J.Biol.Chem., 288, 2013
4GV9
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BU of 4gv9 by Molmil
Lassa nucleoprotein C-terminal domain in complex with triphosphated dsRNA soaking for 5 min
Descriptor: MANGANESE (II) ION, Nucleoprotein, RNA (5'-R(*(GTP)P*GP*GP*C)-3'), ...
Authors:Jiang, X, Huang, Q, Wang, W, Dong, H, Ly, H, Liang, Y, Dong, C.
Deposit date:2012-08-30
Release date:2013-05-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
J.Biol.Chem., 288, 2013
4L4L
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BU of 4l4l by Molmil
Structural Analysis of a Phosphoribosylated Inhibitor in Complex with Human Nicotinamide Phosphoribosyltransferase
Descriptor: 1,2-ETHANEDIOL, 6-({4-[(3,5-difluorophenyl)sulfonyl]benzyl}carbamoyl)-1-(5-O-phosphono-beta-D-ribofuranosyl)imidazo[1,2-a]pyridin-1-ium, Nicotinamide phosphoribosyltransferase, ...
Authors:Oh, A, Ho, Y, Zak, M, Liu, Y, Yuen, P, Zheng, X, Dragovich, S.P, Wang, W.
Deposit date:2013-06-08
Release date:2014-06-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.122 Å)
Cite:Structural and biochemical analyses of the catalysis and potency impact of inhibitor phosphoribosylation by human nicotinamide phosphoribosyltransferase.
Chembiochem, 15, 2014
4NFT
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BU of 4nft by Molmil
Crystal structure of human lnkH2B-h2A.Z-Anp32e
Descriptor: Acidic leucine-rich nuclear phosphoprotein 32 family member E, Histone H2B type 2-E, Histone H2A.Z
Authors:Shan, S, Pan, L, Mao, Z, Wang, W, Sun, J, Dong, Q, Liang, X, Ding, X, Chen, S, Dai, L, Zhang, Z, Zhu, B, Zhou, Z.
Deposit date:2013-11-01
Release date:2014-04-09
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Anp32e, a higher eukaryotic histone chaperone directs preferential recognition for H2A.Z
Cell Res., 24, 2014
6J36
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BU of 6j36 by Molmil
crystal structure of Mycoplasma hyopneumoniae Enolase
Descriptor: Enolase, GLYCEROL, SULFATE ION
Authors:Chen, R, Zhang, S, Gan, R, Xie, X, Feng, Z, Wang, W, Ran, T, Zhang, W, Xiang, Q, Shao, G.
Deposit date:2019-01-04
Release date:2019-05-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Featured Species-Specific Loops Are Found in the Crystal Structure ofMhpEno, a Cell Surface Adhesin FromMycoplasma hyopneumoniae.
Front Cell Infect Microbiol, 9, 2019
4O0Z
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BU of 4o0z by Molmil
Structural and Biochemical Analyses of the Catalysis and Potency Impact of Inhibitor Phosphoribosylation by Human Nicotinamide Phosphoribosyltransferase
Descriptor: N-{4-[(3,5-difluorophenyl)sulfonyl]benzyl}indolizine-6-carboxamide, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION
Authors:Oh, A, Wang, W.
Deposit date:2013-12-14
Release date:2014-06-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.049 Å)
Cite:Structural and biochemical analyses of the catalysis and potency impact of inhibitor phosphoribosylation by human nicotinamide phosphoribosyltransferase.
Chembiochem, 15, 2014
4O0R
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BU of 4o0r by Molmil
Back pocket flexibility provides group-II PAK selectivity for type 1 kinase inhibitors
Descriptor: PF-3758309, Serine/threonine-protein kinase PAK 1
Authors:Rouge, L, Tam, C, Wang, W.
Deposit date:2013-12-14
Release date:2014-02-12
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Back Pocket Flexibility Provides Group II p21-Activated Kinase (PAK) Selectivity for Type I 1/2 Kinase Inhibitors.
J.Med.Chem., 57, 2014
4O0Y
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BU of 4o0y by Molmil
Back pocket flexibility provides group-II PAK selectivity for type 1 kinase inhibitors
Descriptor: 4-[1-(4-amino-1,3,5-triazin-2-yl)-2-(ethylamino)-1H-benzimidazol-6-yl]-2-methylbut-3-yn-2-ol, Serine/threonine-protein kinase PAK 4
Authors:Rouge, L, Tam, C, Wang, W.
Deposit date:2013-12-14
Release date:2014-02-12
Last modified:2014-02-26
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Back Pocket Flexibility Provides Group II p21-Activated Kinase (PAK) Selectivity for Type I 1/2 Kinase Inhibitors.
J.Med.Chem., 57, 2014
4O0T
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BU of 4o0t by Molmil
Back pocket flexibility provides group-II PAK selectivity for type 1 kinase inhibitors
Descriptor: 1-({1-(2-aminopyrimidin-4-yl)-2-[(2-methoxyethyl)amino]-1H-benzimidazol-6-yl}ethynyl)cyclohexanol, Serine/threonine-protein kinase PAK 1
Authors:Oh, A, Tam, C, Wang, W.
Deposit date:2013-12-14
Release date:2014-02-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Back Pocket Flexibility Provides Group II p21-Activated Kinase (PAK) Selectivity for Type I 1/2 Kinase Inhibitors.
J.Med.Chem., 57, 2014
6J9R
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BU of 6j9r by Molmil
Coiled-coil Domain of Drosophila TRIM Protein Brat
Descriptor: Brain tumor protein, GLYCEROL
Authors:Shan, Z, Wang, W.
Deposit date:2019-01-24
Release date:2019-04-24
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the coiled-coil domain of Drosophila TRIM protein Brat.
Proteins, 87, 2019
7VIB
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BU of 7vib by Molmil
Crystal structure of human ACE2 and GX/P2V RBD
Descriptor: Angiotensin-converting enzyme 2, Spike glycoprotein, ZINC ION
Authors:Guo, Y, Cao, W, Jia, N, Wang, W, Yuan, S, Wang, Y.
Deposit date:2021-09-26
Release date:2022-10-05
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of human ACE2 and GX/P2V RBD
To Be Published
7F79
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BU of 7f79 by Molmil
Crystal structure of glutamate dehydrogenase 3 from Candida albicans in complex with alpha-ketoglutarate and NADPH
Descriptor: 2-OXOGLUTARIC ACID, GLYCEROL, Glutamate dehydrogenase, ...
Authors:Li, N, Wang, W, Zeng, X, Liu, M, Li, M, Li, C, Wang, M.
Deposit date:2021-06-28
Release date:2021-07-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of glutamate dehydrogenase 3 from Candida albicans.
Biochem.Biophys.Res.Commun., 570, 2021
7F77
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BU of 7f77 by Molmil
Crystal structure of glutamate dehydrogenase 3 from Candida albicans
Descriptor: Glutamate dehydrogenase
Authors:Li, N, Wang, W, Zeng, X, Liu, M, Li, M, Li, C, Wang, M.
Deposit date:2021-06-28
Release date:2021-07-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.086 Å)
Cite:Crystal structure of glutamate dehydrogenase 3 from Candida albicans.
Biochem.Biophys.Res.Commun., 570, 2021
7L31
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BU of 7l31 by Molmil
Cyro-EM structure of human Glycine Receptor alpha2-beta heteromer, strychnine bound state, 3.8 Angstrom
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alpha-2, Glycine receptor subunit beta,Green fluorescent protein, ...
Authors:Yu, H, Wang, W.
Deposit date:2020-12-17
Release date:2021-09-08
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Characterization of the subunit composition and structure of adult human glycine receptors
Neuron, 109, 2021
7KUY
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BU of 7kuy by Molmil
Cyro-EM structure of human Glycine Receptor alpha2-beta heteromer, strychnine bound state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alpha-2, Glycine receptor subunit beta, ...
Authors:Yu, H, Wang, W.
Deposit date:2020-11-25
Release date:2021-09-08
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Characterization of the subunit composition and structure of adult human glycine receptors
Neuron, 109, 2021
7E1V
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BU of 7e1v by Molmil
Cryo-EM structure of apo hybrid respiratory supercomplex consisting of Mycobacterium tuberculosis complexIII and Mycobacterium smegmatis complexIV
Descriptor: (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, CARDIOLIPIN, ...
Authors:Zhou, S, Wang, W, Gao, Y, Gong, H, Rao, Z.
Deposit date:2021-02-03
Release date:2021-10-13
Last modified:2022-07-27
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Structure of Mycobacterium tuberculosis cytochrome bcc in complex with Q203 and TB47, two anti-TB drug candidates.
Elife, 10, 2021
7E1X
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BU of 7e1x by Molmil
Cryo-EM structure of hybrid respiratory supercomplex consisting of Mycobacterium tuberculosis complexIII and Mycobacterium smegmatis complexIV in presence of TB47
Descriptor: (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, 5-methoxy-2-methyl-~{N}-[[4-[4-[4-(trifluoromethyloxy)phenyl]piperidin-1-yl]phenyl]methyl]pyrazolo[1,5-a]pyridine-3-carboxamide, ...
Authors:Zhou, S, Wang, W, Gao, Y, Gong, H, Rao, Z.
Deposit date:2021-02-03
Release date:2021-10-27
Last modified:2022-07-27
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Structure of Mycobacterium tuberculosis cytochrome bcc in complex with Q203 and TB47, two anti-TB drug candidates.
Elife, 10, 2021

224572

數據於2024-09-04公開中

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