Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
8TZW
DownloadVisualize
BU of 8tzw by Molmil
Crystal structure of 10E8-GT4 scaffold in complex with a human 10E8 inferred germline (10E8-iGL1)
Descriptor: 10E8-GT4 epitope scaffold, 10E8-IGL1 Fab Light Chain, 10E8-IGL1 Fab heavy chain
Authors:Irimia, A, Wilson, I.A.
Deposit date:2023-08-28
Release date:2024-06-12
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 2024
8U03
DownloadVisualize
BU of 8u03 by Molmil
Crystal structure of non-glycosylated 10E8-GT10.1 scaffold in complex with a human 10E8 NGS precursor (10E8-NGS-03)
Descriptor: 10E8-GT10.1 epitope scaffold, 10E8-NGS-03 Fab Light Chain, 10E8-NGS-03 Fab heavy chain, ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2023-08-28
Release date:2024-06-12
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 2024
8U08
DownloadVisualize
BU of 8u08 by Molmil
Crystal structure of 10E8-GT11 scaffold in complex with a human 10E8 inferred germline (10E8-iGL1)
Descriptor: 10E8-GT11 epitope scaffold, 10E8-IGL1 heavy chain, 10E8-IGL1 light chain, ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2023-08-28
Release date:2024-06-12
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 2024
8V2E
DownloadVisualize
BU of 8v2e by Molmil
Crystal structure of B055 scaffold boost immunogen in complex with a mature 10E8 Fab
Descriptor: 10E8 EPITOPE SCAFFOLD B055, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 10E8 FAB HEAVY CHAIN, ...
Authors:Cho, S.Y, Wilson, I.A.
Deposit date:2023-11-22
Release date:2024-06-12
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 25, 2024
5IQ7
DownloadVisualize
BU of 5iq7 by Molmil
Crystal structure of 10E8-S74W Fab in complex with an HIV-1 gp41 peptide.
Descriptor: 10E8-S74W Heavy Chain, 10E8-S74W Light Chain, gp41 MPER peptide
Authors:Ofek, G, Kwon, Y.D, Caruso, W, Kwong, P.D.
Deposit date:2016-03-10
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.2869 Å)
Cite:Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design.
J.Virol., 90, 2016
7BW1
DownloadVisualize
BU of 7bw1 by Molmil
Crystal structure of Steroid 5-alpha-reductase 2 in complex with Finasteride
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-oxo-5-alpha-steroid 4-dehydrogenase 2, SULFATE ION, ...
Authors:Xiao, Q, Zhang, C, Wei, Z.
Deposit date:2020-04-13
Release date:2020-08-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of human steroid 5 alpha-reductase 2 with anti-androgen drug finasteride.
Res Sq, 2020
5IQ9
DownloadVisualize
BU of 5iq9 by Molmil
Crystal structure of 10E8v4 Fab in complex with an HIV-1 gp41 peptide.
Descriptor: 10E8v4 Heavy Chain, 10E8v4 Light Chain, gp41 MPER peptide
Authors:Ofek, G, Kwon, Y.D, Caruso, W, Kwong, P.D.
Deposit date:2016-03-10
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design.
J.Virol., 90, 2016
5JG8
DownloadVisualize
BU of 5jg8 by Molmil
Crystal structure of human acid sphingomyelinase
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Xiong, Z.J, Prive, G.G.
Deposit date:2016-04-19
Release date:2016-07-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of Human Acid Sphingomyelinase Reveals the Role of the Saposin Domain in Activating Substrate Hydrolysis.
J.Mol.Biol., 428, 2016
7WFR
DownloadVisualize
BU of 7wfr by Molmil
Human Nav1.8 with A-803467, class III
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yan, N, Pan, X.J, Huang, X.S, Huang, G.X.
Deposit date:2021-12-27
Release date:2022-08-03
Last modified:2022-09-21
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for high-voltage activation and subtype-specific inhibition of human Na v 1.8.
Proc.Natl.Acad.Sci.USA, 119, 2022
7WE4
DownloadVisualize
BU of 7we4 by Molmil
Human Nav1.8 with A-803467, class I
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yan, N, Pan, X.J, Huang, X.S, Huang, G.X.
Deposit date:2021-12-22
Release date:2022-08-03
Last modified:2022-09-21
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural basis for high-voltage activation and subtype-specific inhibition of human Na v 1.8.
Proc.Natl.Acad.Sci.USA, 119, 2022
7WFW
DownloadVisualize
BU of 7wfw by Molmil
Apo human Nav1.8
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yan, N, Pan, X.J, Huang, X.S, Huang, G.X.
Deposit date:2021-12-27
Release date:2022-08-03
Last modified:2022-09-21
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for high-voltage activation and subtype-specific inhibition of human Na v 1.8.
Proc.Natl.Acad.Sci.USA, 119, 2022
7WEL
DownloadVisualize
BU of 7wel by Molmil
Human Nav1.8 with A-803467, class II
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yan, N, Pan, X.J, Huang, X.S, Huang, G.X.
Deposit date:2021-12-23
Release date:2022-08-03
Last modified:2022-09-21
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis for high-voltage activation and subtype-specific inhibition of human Na v 1.8.
Proc.Natl.Acad.Sci.USA, 119, 2022
5V0Y
DownloadVisualize
BU of 5v0y by Molmil
Solution structure of arenicin-3.
Descriptor: arenicin-3
Authors:Edwards, I.A, Mobli, M.
Deposit date:2017-02-28
Release date:2018-08-08
Last modified:2020-06-10
Method:SOLUTION NMR
Cite:An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria
Nat Commun, 2020
5DIH
DownloadVisualize
BU of 5dih by Molmil
Structure of Haliangium ochraceum BMC-T HO-5812
Descriptor: Microcompartments protein
Authors:Sutter, M, Aussignargues, C, Turmo, A, Kerfeld, C.A.
Deposit date:2015-09-01
Release date:2016-02-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.444 Å)
Cite:Structure and Function of a Bacterial Microcompartment Shell Protein Engineered to Bind a [4Fe-4S] Cluster.
J.Am.Chem.Soc., 138, 2016
5DII
DownloadVisualize
BU of 5dii by Molmil
Structure of an engineered bacterial microcompartment shell protein binding a [4Fe-4S] cluster
Descriptor: IRON/SULFUR CLUSTER, Microcompartments protein
Authors:Sutter, M, Aussignargues, C, Turmo, A, Kerfeld, C.A.
Deposit date:2015-09-01
Release date:2016-02-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.804 Å)
Cite:Structure and Function of a Bacterial Microcompartment Shell Protein Engineered to Bind a [4Fe-4S] Cluster.
J.Am.Chem.Soc., 138, 2016
7KW1
DownloadVisualize
BU of 7kw1 by Molmil
Structure of hSTING in complex with novel carbocyclic pyrimidine CDN-3
Descriptor: (2R,5R,7R,8R,10R,12aR,14R,15aS,16R)-7-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-16-hydroxy-14-[(pyrimidin-4-yl)oxy]-2,10-disulfanyldecahydro-2H,10H-5,8-methano-2lambda~5~,10lambda~5~-cyclopenta[l][1,3,6,9,11,2,10]pentaoxadiphosphacyclotetradecine-2,10-dione, Stimulator of interferon genes protein
Authors:Skene, R.
Deposit date:2020-11-29
Release date:2021-06-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Identification of Novel Carbocyclic Pyrimidine Cyclic Dinucleotide STING Agonists for Antitumor Immunotherapy Using Systemic Intravenous Route.
J.Med.Chem., 64, 2021
7KVX
DownloadVisualize
BU of 7kvx by Molmil
Structure of hSTING in complex with novel carbocyclic pyrimidine CDN 1
Descriptor: (2R,5R,7R,8R,10R,12aR,14R,15aS,16R)-7-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-16-hydroxy-14-[(pyrimidin-4-yl)amino]-2,10-disulfanyldecahydro-2H,10H-5,8-methano-2lambda~5~,10lambda~5~-cyclopenta[l][1,3,6,9,11,2,10]pentaoxadiphosphacyclotetradecine-2,10-dione, Stimulator of interferon genes protein
Authors:Skene, R.
Deposit date:2020-11-29
Release date:2021-06-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Identification of Novel Carbocyclic Pyrimidine Cyclic Dinucleotide STING Agonists for Antitumor Immunotherapy Using Systemic Intravenous Route.
J.Med.Chem., 64, 2021
7KVZ
DownloadVisualize
BU of 7kvz by Molmil
Structure of hSTING in complex with novel carbocyclic pyrimidine CDN-2
Descriptor: (2R,5R,7R,8R,10S,12aR,14R,15aS,16R)-7-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-2,10,16-trihydroxy-14-[(pyrimidin-4-yl)oxy]decahydro-2H,10H-5,8-methano-2lambda~5~,10lambda~5~-cyclopenta[l][1,3,6,9,11,2,10]pentaoxadiphosphacyclotetradecine-2,10-dione, Stimulator of interferon genes protein
Authors:Skene, R.J.
Deposit date:2020-11-29
Release date:2022-02-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Identification of Novel Carbocyclic Pyrimidine Cyclic Dinucleotide STING Agonists for Antitumor Immunotherapy Using Systemic Intravenous Route.
J.Med.Chem., 64, 2021
5WPI
DownloadVisualize
BU of 5wpi by Molmil
The virulence-associated protein HsvA from the fire blight pathogen Erwinia amylovora is a polyamine amidinotransferase
Descriptor: 1,2-ETHANEDIOL, HsvA
Authors:Shanker, S, Lawton, J.
Deposit date:2017-08-04
Release date:2017-11-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The virulence-associated protein HsvA from the fire blight pathogen Erwinia amylovora is a polyamine amidinotransferase.
J. Biol. Chem., 292, 2017
6UCE
DownloadVisualize
BU of 6uce by Molmil
N123-VRC34_pI3 HIV neutralizing antibody in complex with HIV fusion peptide residue 512-519
Descriptor: HIV fusion peptide, N123-VRC34_pI3 heavy chain, N123-VRC34_pI3 light chain
Authors:Xu, K, Kwong, P.D.
Deposit date:2019-09-16
Release date:2020-03-18
Last modified:2020-04-22
Method:X-RAY DIFFRACTION (1.382 Å)
Cite:VRC34-Antibody Lineage Development Reveals How a Required Rare Mutation Shapes the Maturation of a Broad HIV-Neutralizing Lineage.
Cell Host Microbe, 27, 2020
6UCF
DownloadVisualize
BU of 6ucf by Molmil
N123-VRC34_pI4 HIV neutralizing antibody in complex with HIV fusion peptide residue 512-519
Descriptor: HIV fusion peptide, N123-VRC34_pI4 heavy chain, N123-VRC34_pI4 light chain
Authors:Xu, K, Kwong, P.D.
Deposit date:2019-09-16
Release date:2020-03-18
Last modified:2020-04-22
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:VRC34-Antibody Lineage Development Reveals How a Required Rare Mutation Shapes the Maturation of a Broad HIV-Neutralizing Lineage.
Cell Host Microbe, 27, 2020
7E3K
DownloadVisualize
BU of 7e3k by Molmil
Ultrapotent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants
Descriptor: 13G9 heavy chain, 13G9 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Guo, H, Li, T, Liu, F, Gao, Y, Ji, X, Yang, H.
Deposit date:2021-02-09
Release date:2021-09-15
Last modified:2022-03-02
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Potent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants.
Nat Commun, 12, 2021
7E3L
DownloadVisualize
BU of 7e3l by Molmil
Ultrapotent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 58G6 heavy chain, 58G6 light chain, ...
Authors:Guo, H, Li, T, Liu, F, Gao, Y, Ji, X, Yang, H.
Deposit date:2021-02-09
Release date:2021-09-15
Last modified:2022-03-02
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Potent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants.
Nat Commun, 12, 2021
3N2R
DownloadVisualize
BU of 3n2r by Molmil
Structure of neuronal nitric oxide synthase heme domain in complex with 6-(((3R,4R/3S,4S)-4-(3-Phenoxyphenoxy)pyrrolidin-3-yl)methyl)pyridin-2-amine
Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, 6-{[(3R,4R)-4-(3-phenoxyphenoxy)pyrrolidin-3-yl]methyl}pyridin-2-amine, ACETATE ION, ...
Authors:Li, H, Poulos, T.L.
Deposit date:2010-05-18
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-based design, synthesis, and biological evaluation of lipophilic-tailed monocationic inhibitors of neuronal nitric oxide synthase.
Bioorg.Med.Chem., 18, 2010
8IJZ
DownloadVisualize
BU of 8ijz by Molmil
anti-VEGF mutant
Descriptor: anti-VEGF nanobody
Authors:Qian, F, Zhu, S.Q.
Deposit date:2023-02-28
Release date:2023-12-27
Method:ELECTRON CRYSTALLOGRAPHY (2.1 Å)
Cite:Polymorphic nanobody crystals as long-acting intravitreal therapy for wet age-related macular degeneration.
Bioeng Transl Med, 8, 2023

221051

數據於2024-06-12公開中

PDB statisticsPDBj update infoContact PDBjnumon