Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
2A5S
DownloadVisualize
BU of 2a5s by Molmil
Crystal Structure Of The NR2A Ligand Binding Core In Complex With Glutamate
Descriptor: GLUTAMIC ACID, N-methyl-D-aspartate receptor NMDAR2A subunit
Authors:Furukawa, H, Singh, S.K, Mancusso, R, Gouaux, E.
Deposit date:2005-06-30
Release date:2005-11-15
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Subunit arrangement and function in NMDA receptors
Nature, 438, 2005
2A5T
DownloadVisualize
BU of 2a5t by Molmil
Crystal Structure Of The NR1/NR2A ligand-binding cores complex
Descriptor: GLUTAMIC ACID, GLYCINE, N-methyl-D-aspartate receptor NMDAR1-4a subunit, ...
Authors:Furukawa, H, Singh, S.K, Mancusso, R, Gouaux, E.
Deposit date:2005-06-30
Release date:2005-11-15
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:Subunit arrangement and function in NMDA receptors
Nature, 438, 2005
1PB7
DownloadVisualize
BU of 1pb7 by Molmil
CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH GLYCINE AT 1.35 ANGSTROMS RESOLUTION
Descriptor: GLYCINE, N-methyl-D-aspartate Receptor Subunit 1
Authors:Furukawa, H, Gouaux, E.
Deposit date:2003-05-14
Release date:2003-06-24
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
1PB8
DownloadVisualize
BU of 1pb8 by Molmil
CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH D-SERINE AT 1.45 ANGSTROMS RESOLUTION
Descriptor: D-SERINE, N-methyl-D-aspartate Receptor Subunit 1
Authors:Furukawa, H, Gouaux, E.
Deposit date:2003-05-14
Release date:2003-06-24
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
1PB9
DownloadVisualize
BU of 1pb9 by Molmil
CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH D-CYCLOSERINE AT 1.60 ANGSTROMS RESOLUTION
Descriptor: (R)-4-AMINO-ISOXAZOLIDIN-3-ONE, N-methyl-D-aspartate Receptor Subunit 1
Authors:Furukawa, H, Gouaux, E.
Deposit date:2003-05-14
Release date:2003-06-24
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
1PBQ
DownloadVisualize
BU of 1pbq by Molmil
CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH 5,7-DICHLOROKYNURENIC ACID (DCKA) AT 1.90 ANGSTROMS RESOLUTION
Descriptor: 5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID, N-methyl-D-aspartate Receptor Subunit 1
Authors:Furukawa, H, Gouaux, E.
Deposit date:2003-05-14
Release date:2003-07-29
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
6CNA
DownloadVisualize
BU of 6cna by Molmil
GluN1-GluN2B NMDA receptors with exon 5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
Authors:Furukawa, H, Grant, T, Grigorieff, N.
Deposit date:2018-03-07
Release date:2018-10-03
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural Mechanism of Functional Modulation by Gene Splicing in NMDA Receptors.
Neuron, 98, 2018
3OEM
DownloadVisualize
BU of 3oem by Molmil
Crystal structure of GluN2D ligand-binding core in complex with N-methyl-D-aspartate
Descriptor: Glutamate [NMDA] receptor subunit epsilon-4, N-methyl-D-aspartic acid
Authors:Simorowski, N, Furukawa, H.
Deposit date:2010-08-12
Release date:2011-05-11
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors.
Nat Commun, 2, 2011
8S90
DownloadVisualize
BU of 8s90 by Molmil
Cryo-EM structure of octameric human CALHM1 (I109W) in complex with ruthenium red (C1)
Descriptor: Calcium homeostasis modulator protein 1, ruthenium(6+) azanide pentaamino(oxido)ruthenium (1/4/2)
Authors:Syrjanen, J.L, Furukawa, H.
Deposit date:2023-03-27
Release date:2023-07-26
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.73 Å)
Cite:Structure of human CALHM1 reveals key locations for channel regulation and blockade by ruthenium red.
Nat Commun, 14, 2023
8S8Z
DownloadVisualize
BU of 8s8z by Molmil
Cryo-EM structure of octameric human CALHM1 (I109W) in complex with ruthenium red
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Calcium homeostasis modulator protein 1, ruthenium(6+) azanide pentaamino(oxido)ruthenium (1/4/2)
Authors:Syrjanen, J.L, Furukawa, H.
Deposit date:2023-03-27
Release date:2023-07-26
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.91 Å)
Cite:Structure of human CALHM1 reveals key locations for channel regulation and blockade by ruthenium red.
Nat Commun, 14, 2023
9ARE
DownloadVisualize
BU of 9are by Molmil
Rat GluN1-GluN2B NMDA receptor channel in complex with glycine, glutamate, and EU-1622-A, in open-channel conformation
Descriptor: GLUTAMIC ACID, GLYCINE, Glutamate receptor ionotropic, ...
Authors:Chou, T.-H, Furukawa, H.
Deposit date:2024-02-23
Release date:2024-07-31
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Molecular mechanism of ligand gating and opening of NMDA receptor.
Nature, 632, 2024
9ARF
DownloadVisualize
BU of 9arf by Molmil
Rat GluN1-GluN2B NMDA receptor channel in complex with glycine, glutamate, and EU-1622-A, in nonactive1 conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
Authors:Chou, T.-H, Furukawa, H.
Deposit date:2024-02-23
Release date:2024-07-31
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Molecular mechanism of ligand gating and opening of NMDA receptor.
Nature, 632, 2024
9BIB
DownloadVisualize
BU of 9bib by Molmil
Rat GluN1-GluN2B NMDA receptor channel in complex with glycine, glutamate, and EU-1622-A, in open-channel conformation, C1 symmetry
Descriptor: GLUTAMIC ACID, GLYCINE, Glutamate receptor, ...
Authors:Chou, T.-H, Furukawa, H.
Deposit date:2024-04-23
Release date:2024-07-31
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.81 Å)
Cite:Molecular mechanism of ligand gating and opening of NMDA receptor.
Nature, 632, 2024
2QTS
DownloadVisualize
BU of 2qts by Molmil
Structure of an acid-sensing ion channel 1 at 1.9 A resolution and low pH
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel, CHLORIDE ION, ...
Authors:Jasti, J, Furukawa, H, Gonzales, E.B, Gouaux, E.
Deposit date:2007-08-02
Release date:2007-09-25
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of acid-sensing ion channel 1 at 1.9A resolution and low pH
Nature, 449, 2007
7SAB
DownloadVisualize
BU of 7sab by Molmil
Phencyclidine-bound GluN1a-GluN2B NMDA receptors
Descriptor: 1-(PHENYL-1-CYCLOHEXYL)PIPERIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Chou, T.-H, Furukawa, H.
Deposit date:2021-09-22
Release date:2022-07-20
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural insights into binding of therapeutic channel blockers in NMDA receptors.
Nat.Struct.Mol.Biol., 29, 2022
7SAD
DownloadVisualize
BU of 7sad by Molmil
Memantine-bound GluN1a-GluN2B NMDA receptors
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
Authors:Chou, T.-H, Furukawa, H.
Deposit date:2021-09-22
Release date:2022-07-20
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.96 Å)
Cite:Structural insights into binding of therapeutic channel blockers in NMDA receptors.
Nat.Struct.Mol.Biol., 29, 2022
7SAA
DownloadVisualize
BU of 7saa by Molmil
Glycine and glutamate bound GluN1a-GluN2B NMDA receptors in non-active 1 conformation at 2.97 Angstrom resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
Authors:Chou, T.-H, Furukawa, H.
Deposit date:2021-09-22
Release date:2022-07-20
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Structural insights into binding of therapeutic channel blockers in NMDA receptors.
Nat.Struct.Mol.Biol., 29, 2022
7SAC
DownloadVisualize
BU of 7sac by Molmil
S-(+)-ketamine bound GluN1a-GluN2B NMDA receptors at 3.69 Angstrom resolution
Descriptor: (2~{S})-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Chou, T.-H, Furukawa, H.
Deposit date:2021-09-22
Release date:2022-07-20
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.69 Å)
Cite:Structural insights into binding of therapeutic channel blockers in NMDA receptors.
Nat.Struct.Mol.Biol., 29, 2022
8E96
DownloadVisualize
BU of 8e96 by Molmil
Glycine and glutamate bound Human GluN1a-GluN2D NMDA receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, GLYCINE, ...
Authors:Kang, H, Furukawa, H.
Deposit date:2022-08-26
Release date:2022-12-07
Last modified:2022-12-14
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.
Mol.Cell, 82, 2022
8G18
DownloadVisualize
BU of 8g18 by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-108
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, NMDA 1, ...
Authors:Regan, M.C, Furukawa, H.
Deposit date:2023-02-01
Release date:2023-03-01
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Novel GluN2B-Selective NMDA Receptor Negative Allosteric Modulator Possesses Intrinsic Analgesic Properties and Enhances Analgesia of Morphine in a Rodent Tail Flick Pain Model.
Acs Chem Neurosci, 14, 2023
8E97
DownloadVisualize
BU of 8e97 by Molmil
PYD-106-bound Human GluN1a-GluN2C NMDA receptor in splayed conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
Authors:Chou, T.-H, Furukawa, H.
Deposit date:2022-08-26
Release date:2022-12-07
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (4.19 Å)
Cite:Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.
Mol.Cell, 82, 2022
8E94
DownloadVisualize
BU of 8e94 by Molmil
PYD-106-bound Human GluN1a-GluN2C NMDA receptor in intact conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Chou, T.-H, Furukawa, H.
Deposit date:2022-08-26
Release date:2022-12-07
Last modified:2022-12-14
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.
Mol.Cell, 82, 2022
8E93
DownloadVisualize
BU of 8e93 by Molmil
D-cycloserine and glutamate bound Human GluN1a-GluN2C NMDA receptor in splayed conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
Authors:Chou, T.-H, Furukawa, H.
Deposit date:2022-08-26
Release date:2022-12-07
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.
Mol.Cell, 82, 2022
8E99
DownloadVisualize
BU of 8e99 by Molmil
Human GluN1a-GluN2A-GluN2C triheteromeric NMDA receptor in complex with Nb-4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
Authors:Chou, T.-H, Furukawa, H.
Deposit date:2022-08-26
Release date:2022-12-07
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (4.24 Å)
Cite:Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.
Mol.Cell, 82, 2022
8E92
DownloadVisualize
BU of 8e92 by Molmil
D-cycloserine and glutamate bound Human GluN1a-GluN2C NMDA receptor in intact conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
Authors:Chou, T.-H, Furukawa, H.
Deposit date:2022-08-26
Release date:2022-12-07
Last modified:2022-12-14
Method:ELECTRON MICROSCOPY (3.96 Å)
Cite:Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.
Mol.Cell, 82, 2022

227111

数据于2024-11-06公开中

PDB statisticsPDBj update infoContact PDBjnumon