7SAD

Memantine-bound GluN1a-GluN2B NMDA receptors

Summary for 7SAD

• Entry DOI: 10.2210/pdb7sad/pdb
• Related: 7SAA 7SAB 7SAC
• EMDB information: 24946 24947 24948 24949
• Descriptor: Glutamate receptor ionotropic, NMDA 1, Glutamate receptor ionotropic, NMDA 2B, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: ligand-gated ion channel, ionotropic glutamate receptor, synaptic protein, voltage-gate ion channel, transport protein
• Biological source: Rattus norvegicus (Rat); More
• Total number of polymer chains: 4
• Total formula weight: 391673.03

Authors

Chou, T.-H.,Furukawa, H. (deposition date: 2021-09-22, release date: 2022-07-20)

• Primary citation: Chou, T.H.,Epstein, M.,Michalski, K.,Fine, E.,Biggin, P.C.,Furukawa, H.; Structural insights into binding of therapeutic channel blockers in NMDA receptors.; Nat.Struct.Mol.Biol., 29:507-518, 2022; PubMed: 35637422; DOI: 10.1038/s41594-022-00772-0

Experimental method

ELECTRON MICROSCOPY (3.96 Å)