1PB8
| |
1PB9
| |
1PBQ
| |
1PB7
| |
2A5S
| Crystal Structure Of The NR2A Ligand Binding Core In Complex With Glutamate | Descriptor: | GLUTAMIC ACID, N-methyl-D-aspartate receptor NMDAR2A subunit | Authors: | Furukawa, H, Singh, S.K, Mancusso, R, Gouaux, E. | Deposit date: | 2005-06-30 | Release date: | 2005-11-15 | Last modified: | 2017-07-26 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Subunit arrangement and function in NMDA receptors Nature, 438, 2005
|
|
2A5T
| Crystal Structure Of The NR1/NR2A ligand-binding cores complex | Descriptor: | GLUTAMIC ACID, GLYCINE, N-methyl-D-aspartate receptor NMDAR1-4a subunit, ... | Authors: | Furukawa, H, Singh, S.K, Mancusso, R, Gouaux, E. | Deposit date: | 2005-06-30 | Release date: | 2005-11-15 | Last modified: | 2017-07-26 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Subunit arrangement and function in NMDA receptors Nature, 438, 2005
|
|
6CNA
| GluN1-GluN2B NMDA receptors with exon 5 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | Authors: | Furukawa, H, Grant, T, Grigorieff, N. | Deposit date: | 2018-03-07 | Release date: | 2018-10-03 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural Mechanism of Functional Modulation by Gene Splicing in NMDA Receptors. Neuron, 98, 2018
|
|
6E7R
| |
8USX
| Glycine-bound GluN1a-3A NMDA receptor | Descriptor: | Glutamate receptor ionotropic, NMDA 1, NMDA 3A | Authors: | Michalski, K, Furukawa, H. | Deposit date: | 2023-10-30 | Release date: | 2024-04-17 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structure and function of GluN1-3A NMDA receptor excitatory glycine receptor channel. Sci Adv, 10, 2024
|
|
8UUE
| |
5FXI
| GluN1b-GluN2B NMDA receptor structure in non-active-2 conformation | Descriptor: | N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B | Authors: | Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H. | Deposit date: | 2016-03-02 | Release date: | 2016-05-11 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (6.4 Å) | Cite: | Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil. Nature, 534, 2016
|
|
5FXK
| GluN1b-GluN2B NMDA receptor structure-Class Y | Descriptor: | N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B | Authors: | Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H. | Deposit date: | 2016-03-02 | Release date: | 2016-05-11 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (6.4 Å) | Cite: | Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil. Nature, 534, 2016
|
|
5FXG
| GLUN1B-GLUN2B NMDA RECEPTOR IN ACTIVE CONFORMATION | Descriptor: | N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B | Authors: | Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H. | Deposit date: | 2016-03-02 | Release date: | 2016-05-11 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (6.8 Å) | Cite: | Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil. Nature, 534, 2016
|
|
6E7T
| |
4NF6
| Crystal structure of GluN1/GluN2A ligand-binding domain in complex with glycine and PPDA | Descriptor: | (2S,3R)-1-(phenanthren-2-ylcarbonyl)piperazine-2,3-dicarboxylic acid, GLYCINE, Glutamate receptor ionotropic, ... | Authors: | Jespersen, A, Tajima, N, Furukawa, H. | Deposit date: | 2013-10-30 | Release date: | 2014-03-12 | Last modified: | 2017-08-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Insights into Competitive Antagonism in NMDA Receptors. Neuron, 81, 2014
|
|
4NF8
| Crystal structure of GluN1/GluN2A ligand-binding domain in complex with glycine and glutamate in PEG2000MME | Descriptor: | GLUTAMIC ACID, GLYCINE, Glutamate receptor ionotropic, ... | Authors: | Jespersen, A, Tajima, N, Furukawa, H. | Deposit date: | 2013-10-30 | Release date: | 2014-03-12 | Last modified: | 2017-08-09 | Method: | X-RAY DIFFRACTION (1.856 Å) | Cite: | Structural Insights into Competitive Antagonism in NMDA Receptors. Neuron, 81, 2014
|
|
8S90
| |
8S8Z
| Cryo-EM structure of octameric human CALHM1 (I109W) in complex with ruthenium red | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Calcium homeostasis modulator protein 1, ruthenium(6+) azanide pentaamino(oxido)ruthenium (1/4/2) | Authors: | Syrjanen, J.L, Furukawa, H. | Deposit date: | 2023-03-27 | Release date: | 2023-07-26 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.91 Å) | Cite: | Structure of human CALHM1 reveals key locations for channel regulation and blockade by ruthenium red. Nat Commun, 14, 2023
|
|
8USW
| CNQX-bound GluN1a-3A NMDA receptor | Descriptor: | 7-nitro-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-carbonitrile, Glutamate receptor ionotropic, NMDA 1, ... | Authors: | Michalski, K, Furukawa, H. | Deposit date: | 2023-10-30 | Release date: | 2024-04-17 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (4.23 Å) | Cite: | Structure and function of GluN1-3A NMDA receptor excitatory glycine receptor channel. Sci Adv, 10, 2024
|
|
8E96
| Glycine and glutamate bound Human GluN1a-GluN2D NMDA receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, GLYCINE, ... | Authors: | Kang, H, Furukawa, H. | Deposit date: | 2022-08-26 | Release date: | 2022-12-07 | Last modified: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82, 2022
|
|
8E93
| D-cycloserine and glutamate bound Human GluN1a-GluN2C NMDA receptor in splayed conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | Authors: | Chou, T.-H, Furukawa, H. | Deposit date: | 2022-08-26 | Release date: | 2022-12-07 | Last modified: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3.71 Å) | Cite: | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82, 2022
|
|
8E97
| PYD-106-bound Human GluN1a-GluN2C NMDA receptor in splayed conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | Authors: | Chou, T.-H, Furukawa, H. | Deposit date: | 2022-08-26 | Release date: | 2022-12-07 | Last modified: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (4.19 Å) | Cite: | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82, 2022
|
|
8E94
| PYD-106-bound Human GluN1a-GluN2C NMDA receptor in intact conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Chou, T.-H, Furukawa, H. | Deposit date: | 2022-08-26 | Release date: | 2022-12-07 | Last modified: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3.72 Å) | Cite: | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82, 2022
|
|
8E92
| D-cycloserine and glutamate bound Human GluN1a-GluN2C NMDA receptor in intact conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | Authors: | Chou, T.-H, Furukawa, H. | Deposit date: | 2022-08-26 | Release date: | 2022-12-07 | Last modified: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3.96 Å) | Cite: | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82, 2022
|
|
8E98
| D-cycloserine and glutamate bound Human GluN1a-GluN2C NMDA receptor in nanodisc - intact conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, NMDA 1, ... | Authors: | Chou, T.-H, Furukawa, H. | Deposit date: | 2022-08-26 | Release date: | 2022-12-07 | Last modified: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82, 2022
|
|