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4P4N
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BU of 4p4n by Molmil
Crystal Structure of Mycobacterium tuberculosis Shikimate Dehydrogenase
Descriptor: SULFATE ION, Shikimate 5-dehydrogenase AroE (5-dehydroshikimate reductase)
Authors:Lalgondar, M, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2014-03-12
Release date:2015-03-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of Mycobacterium tuberculosis Shikimate Dehydrogenase
To Be Published
4ZOJ
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BU of 4zoj by Molmil
Methylsulfanyl-containing inhibitor bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 4-methyl-2-{[2-methyl-6-(methylsulfanyl)phenyl]amino}benzoic acid, Anthranilate phosphoribosyltransferase, ...
Authors:Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
Deposit date:2015-05-06
Release date:2016-05-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Inhibitor bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD).
To be Published
4ZOF
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BU of 4zof by Molmil
Lobenzarit-like inhibitor bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-[(2-carboxy-5-nitrophenyl)amino]-3-methylbenzoic acid, Anthranilate phosphoribosyltransferase, ...
Authors:Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
Deposit date:2015-05-06
Release date:2016-05-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Inhibitor bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD).
To be Published
4ZOK
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BU of 4zok by Molmil
Methylsulfonyl-containing inhibitor bound in the substrate capture site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 4-methyl-2-{[2-methyl-6-(methylsulfonyl)phenyl]amino}benzoic acid, Anthranilate phosphoribosyltransferase, ...
Authors:Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
Deposit date:2015-05-06
Release date:2016-05-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Inhibitor bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD).
To be Published
5C2L
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BU of 5c2l by Molmil
Magnesium soaked into the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
Descriptor: Anthranilate phosphoribosyltransferase, IMIDAZOLE, MAGNESIUM ION
Authors:Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
Deposit date:2015-06-16
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.009 Å)
Cite:Binding and mimicking of the phosphate-rich substrate, PRPP
To Be Published
5BYT
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BU of 5byt by Molmil
PRPP complexed with a single Mg in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, MAGNESIUM ION
Authors:Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
Deposit date:2015-06-11
Release date:2016-07-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Binding and mimicking of the phosphate-rich substrate, PRPP.
To be Published
5C7S
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BU of 5c7s by Molmil
PRPP complexed with two Mn2+ in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, MANGANESE (II) ION
Authors:Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
Deposit date:2015-06-24
Release date:2016-06-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Binding and mimicking of the phosphate-rich substrate, PRPP
To Be Published
5BO2
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BU of 5bo2 by Molmil
Bianthranilate-like inhibitor with 4-atom "line" and phosphonate "hook" fishing for hydrogen bond donors in Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
Descriptor: 2-[(2-carboxyphenyl)amino]-5-(3-phosphonopropoxy)benzoic acid, Anthranilate phosphoribosyltransferase, IMIDAZOLE
Authors:Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
Deposit date:2015-05-27
Release date:2016-06-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Binding and mimicking of the phosphate-rich substrate, PRPP.
To be Published
5BNE
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BU of 5bne by Molmil
Bianthranilate-like inhibitor with 6 atom "line" and phosphonate "hook" fishing for hydrogen bond donors in Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
Descriptor: 2-[(2-carboxyphenyl)amino]-5-[(5-phosphonopentyl)oxy]benzoic acid, Anthranilate phosphoribosyltransferase, IMIDAZOLE
Authors:Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
Deposit date:2015-05-26
Release date:2016-05-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Binding and mimicking of the phosphate-rich substrate, PRPP.
To be Published
1NFF
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BU of 1nff by Molmil
Crystal structure of Rv2002 gene product from Mycobacterium tuberculosis
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative oxidoreductase Rv2002
Authors:Yang, J.K, Park, M.S, Waldo, G.S, Suh, S.W, TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-12-14
Release date:2002-12-30
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Directed evolution approach to a structural genomics project: Rv2002 from Mycobacterium tuberculosis
Proc.Natl.Acad.Sci.USA, 100, 2003
1NFR
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BU of 1nfr by Molmil
Rv2002 gene product from Mycobacterium tuberculosis
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative oxidoreductase Rv2002
Authors:Yang, J.K, Park, M.S, Waldo, G.S, Suh, S.W, TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-12-16
Release date:2002-12-30
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Directed evolution approach to a structural genomics project: Rv2002 from Mycobacterium tuberculosis
Proc.Natl.Acad.Sci.USA, 100, 2003
4GZR
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BU of 4gzr by Molmil
Crystal structure of the Mycobacterium tuberculosis H37Rv EsxOP (Rv2346c-Rv2347c) complex in space group C2221
Descriptor: ESAT-6-like protein 6, ESAT-6-like protein 7, SULFATE ION
Authors:Arbing, M.A, Chan, S, He, Q, Harris, L, Zhou, T.T, Kuo, E, Ahn, C.J, Eisenberg, D, TB Structural Genomics Consortium (TBSGC), Integrated Center for Structure and Function Innovation (ISFI)
Deposit date:2012-09-06
Release date:2012-09-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.553 Å)
Cite:Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions.
Plos One, 8, 2013
1NFQ
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BU of 1nfq by Molmil
Rv2002 gene product from Mycobacterium tuberculosis
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Androsterone, Putative oxidoreductase Rv2002
Authors:Yang, J.K, Park, M.S, Waldo, G.S, Suh, S.W, TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-12-15
Release date:2002-12-30
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Directed evolution approach to a structural genomics project: Rv2002 from Mycobacterium tuberculosis
Proc.Natl.Acad.Sci.USA, 100, 2003
2G38
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BU of 2g38 by Molmil
A PE/PPE Protein Complex from Mycobacterium tuberculosis
Descriptor: MANGANESE (II) ION, PE FAMILY PROTEIN, PPE FAMILY PROTEIN
Authors:Strong, M, Sawaya, M.R, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
Deposit date:2006-02-17
Release date:2006-03-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Toward the structural genomics of complexes: Crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2OZ5
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BU of 2oz5 by Molmil
Crystal structure of Mycobacterium tuberculosis protein tyrosine phosphatase PtpB in complex with the specific inhibitor OMTS
Descriptor: Phosphotyrosine protein phosphatase ptpb, {(3-CHLOROBENZYL)[(5-{[(3,3-DIPHENYLPROPYL)AMINO]SULFONYL}-2-THIENYL)METHYL]AMINO}(OXO)ACETIC ACID
Authors:Grundner, C, Gee, C.L, Alber, T, TB Structural Genomics Consortium (TBSGC)
Deposit date:2007-02-23
Release date:2007-05-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Selective Inhibition of Mycobacterium tuberculosis Protein Tyrosine Phosphatase PtpB.
Structure, 15, 2007
1NXJ
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BU of 1nxj by Molmil
Structure of Rv3853 from Mycobacterium tuberculosis
Descriptor: GLYOXYLIC ACID, L(+)-TARTARIC ACID, Probable S-adenosylmethionine:2-demethylmenaquinone methyltransferase
Authors:Johnston, J.M, Arcus, V.L, Baker, E.N, TB Structural Genomics Consortium (TBSGC)
Deposit date:2003-02-10
Release date:2003-07-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of a Putative Methyltransferase from Mycobacterium tuberculosis: Misannotation of a Genome Clarified by Protein Structural Analysis
J.Bacteriol., 185, 2003
1MO5
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BU of 1mo5 by Molmil
RECA-ATP-GAMMA-S-MG COMPLEX
Descriptor: PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, RecA
Authors:Datta, S, Ganesh, N, Chandra, N.R, TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-09-07
Release date:2003-02-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structural studies on MtRecA-nucleotide complexes: Insights into DNA and nucleotide binding and the structural signature of NTP recognition
Proteins, 50, 2003
1MO4
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BU of 1mo4 by Molmil
RECA-ATP-GAMMA-S COMPLEX
Descriptor: PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, RecA
Authors:Datta, S, Ganesh, N, Chandra, N.R, TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-09-07
Release date:2003-02-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural studies on MtRecA-nucleotide complexes: Insights into DNA and nucleotide binding and the structural signature of NTP recognition
Proteins, 50, 2003
1MO3
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BU of 1mo3 by Molmil
RECA-ADP COMPLEX
Descriptor: ADENOSINE-5'-DIPHOSPHATE, RecA
Authors:Datta, S, Ganesh, N, Chandra, N.R, TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-09-07
Release date:2003-02-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural studies on MtRecA-nucleotide complexes: Insights into DNA and nucleotide binding and the structural signature of NTP recognition
Proteins, 50, 2003
1QPQ
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BU of 1qpq by Molmil
Structure of Quinolinic Acid Phosphoribosyltransferase from Mycobacterium Tuberculosis: A Potential TB Drug Target
Descriptor: QUINOLINATE PHOSPHORIBOSYLTRANSFERASE, QUINOLINIC ACID, SULFATE ION
Authors:Sharma, V, Grubmeyer, C, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:1998-11-20
Release date:1998-11-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of quinolinic acid phosphoribosyltransferase from Mycobacterium tuberculosis: a potential TB drug target.
Structure, 6, 1998
2QKX
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BU of 2qkx by Molmil
N-acetyl glucosamine 1-phosphate uridyltransferase from Mycobacterium tuberculosis complex with N-acetyl glucosamine 1-phosphate
Descriptor: 2-acetamido-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, Bifunctional protein glmU
Authors:Zhang, Z, Squire, C.J, Baker, E.N, TB Structural Genomics Consortium (TBSGC)
Deposit date:2007-07-11
Release date:2008-07-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure and function of GlmU from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 65, 2009
1RFE
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BU of 1rfe by Molmil
Crystal structure of conserved hypothetical protein Rv2991 from Mycobacterium tuberculosis
Descriptor: hypothetical protein Rv2991
Authors:Benini, S, Haouz, A, Proux, F, Betton, J.M, Alzari, P, Dodson, G.G, Wilson, K.S, TB Structural Genomics Consortium (TBSGC)
Deposit date:2003-11-08
Release date:2004-12-28
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of Rv2991 from Mycobacterium tuberculosis: An F420binding protein with unknown function.
J. Struct. Biol., 2019
2O0T
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BU of 2o0t by Molmil
The three dimensional structure of diaminopimelate decarboxylase from Mycobacterium tuberculosis reveals a tetrameric enzyme organisation
Descriptor: Diaminopimelate decarboxylase, SULFATE ION
Authors:Weyand, S, Kefala, G, Weiss, M.S, TB Structural Genomics Consortium (TBSGC)
Deposit date:2006-11-28
Release date:2007-02-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:The three-dimensional structure of diaminopimelate decarboxylase from Mycobacterium tuberculosis reveals a tetrameric enzyme organisation.
J Struct Funct Genomics, 10, 2009
1NYO
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BU of 1nyo by Molmil
Solution structure of the antigenic TB protein MPT70/MPB70
Descriptor: Immunogenic protein MPT70
Authors:Bloemink, M.J, Dentten, E, Hewinson, R.G, Williamson, R.A, Carr, M.D, TB Structural Genomics Consortium (TBSGC)
Deposit date:2003-02-13
Release date:2003-08-19
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:Solution structure of the Mycobacterium tuberculosis complex protein MPB70: from tuberculosis pathogenesis to inherited human corneal desease
J.Biol.Chem., 278, 2003
1MO6
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BU of 1mo6 by Molmil
RECA-DATP-MG COMPLEX
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, RecA
Authors:Datta, S, Ganesh, N, Chandra, N.R, TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-09-07
Release date:2003-02-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural studies on MtRecA-nucleotide complexes: Insights into DNA and nucleotide binding and the structural signature of NTP recognition
Proteins, 50, 2003

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数据于2025-07-09公开中

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