4ZOJ
Methylsulfanyl-containing inhibitor bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
Summary for 4ZOJ
Entry DOI | 10.2210/pdb4zoj/pdb |
Related | 3QR9 4GIU 4ZOF 4ZOK |
Descriptor | Anthranilate phosphoribosyltransferase, MAGNESIUM ION, 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, ... (7 entities in total) |
Functional Keywords | inhibitor, complex, lobenzarit-like analogue, tb structural genomics consortium, tbsgc, phosphoribosyltransferase, magnesium binding, phosphoribosylpyrophosphate, prpp, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Mycobacterium tuberculosis H37Ra |
Total number of polymer chains | 2 |
Total formula weight | 79512.19 |
Authors | Evans, G.L.,Baker, E.N.,Lott, J.S.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2015-05-06, release date: 2016-05-11, Last modification date: 2023-09-27) |
Primary citation | Evans, G.L.,Baker, E.N.,Lott, J.S. Inhibitor bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD). To be Published, |
Experimental method | X-RAY DIFFRACTION (1.96 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)