1QPQ

Structure of Quinolinic Acid Phosphoribosyltransferase from Mycobacterium Tuberculosis: A Potential TB Drug Target

Summary for 1QPQ

Entry DOI	10.2210/pdb1qpq/pdb
Descriptor	QUINOLINATE PHOSPHORIBOSYLTRANSFERASE, SULFATE ION, QUINOLINIC ACID, ... (4 entities in total)
Functional Keywords	type ii prtase, de novo nad biosynthesis, prpp, phosphoribosyl transferase, quinolinic acid, structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc, transferase
Biological source	Mycobacterium tuberculosis H37Rv
Total number of polymer chains	6
Total formula weight	180684.27
Authors	Sharma, V.,Grubmeyer, C.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (deposition date: 1998-11-20, release date: 1998-11-25, Last modification date: 2023-12-27)
Primary citation	Sharma, V.,Grubmeyer, C.,Sacchettini, J.C. Crystal structure of quinolinic acid phosphoribosyltransferase from Mycobacterium tuberculosis: a potential TB drug target. Structure, 6:1587-1599, 1998 Cited by PubMed: 9862811 DOI: 10.1016/S0969-2126(98)00156-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.45 Å)

Structure validation