5B1J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5b1j by Molmil](/molmil-images/mine/5b1j) | Crystal structure of the electron-transfer complex of copper nitrite reductase with a cupredoxin | Descriptor: | Blue copper protein, COPPER (II) ION, Copper-containing nitrite reductase | Authors: | Nojiri, M, Koteishi, H, Yoneda, R, Hira, D. | Deposit date: | 2015-12-04 | Release date: | 2016-11-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure and Function of Copper Nitrite Reductase Metalloenzymes in denitrification: Applications and Environmental impacts, 2016
|
|
7CAO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7cao by Molmil](/molmil-images/mine/7cao) | Crystal structure of red chromoprotein from Olindias formosa | Descriptor: | Chromoprotein | Authors: | Nakashima, R, Zhai, L, Ike, Y, Matsudz, T, Nagai, T. | Deposit date: | 2020-06-09 | Release date: | 2022-04-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure-based analysis and evolution of a monomerized red-colored chromoprotein from the Olindias formosa jellyfish. Protein Sci., 31, 2022
|
|
7DCF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7dcf by Molmil](/molmil-images/mine/7dcf) | Crystal structure of EHMT2 SET domain in complex with compound 10 | Descriptor: | 5'-methoxy-6'-(1-methyl-2,3,4,7-tetrahydroazepin-5-yl)spiro[cyclobutane-1,3'-indole]-2'-amine, Histone-lysine N-methyltransferase EHMT2, S-ADENOSYLMETHIONINE, ... | Authors: | Suzuki, M, Katayama, K. | Deposit date: | 2020-10-26 | Release date: | 2021-02-10 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Discovery of DS79932728: A Potent, Orally Available G9a/GLP Inhibitor for Treating beta-Thalassemia and Sickle Cell Disease. Acs Med.Chem.Lett., 12, 2021
|
|
2VJ2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2vj2 by Molmil](/molmil-images/mine/2vj2) | Human Jagged-1, domains DSL and EGFs1-3 | Descriptor: | D-MALATE, JAGGED-1 | Authors: | Johnson, S, Cordle, J, Tay, J.Z, Roversi, P, Handford, P.A, Lea, S.M. | Deposit date: | 2007-12-06 | Release date: | 2008-07-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A Conserved Face of the Jagged/Serrate Dsl Domain is Involved in Notch Trans-Activation and Cis-Inhibition. Nat.Struct.Mol.Biol., 15, 2008
|
|
2VJ3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2vj3 by Molmil](/molmil-images/mine/2vj3) | Human Notch-1 EGFs 11-13 | Descriptor: | CALCIUM ION, CHLORIDE ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1, ... | Authors: | Johnson, S, Cordle, J, Tay, J.Z, Roversi, P, Lea, S.M. | Deposit date: | 2007-12-06 | Release date: | 2008-07-29 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A Conserved Face of the Jagged/Serrate Dsl Domain is Involved in Notch Trans-Activation and Cis-Inhibition. Nat.Struct.Mol.Biol., 15, 2008
|
|
6DD6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dd6 by Molmil](/molmil-images/mine/6dd6) | |
1BTC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1btc by Molmil](/molmil-images/mine/1btc) | THREE-DIMENSIONAL STRUCTURE OF SOYBEAN BETA-AMYLASE DETERMINED AT 3.0 ANGSTROMS RESOLUTION: PRELIMINARY CHAIN TRACING OF THE COMPLEX WITH ALPHA-CYCLODEXTRIN | Descriptor: | BETA-AMYLASE, BETA-MERCAPTOETHANOL, Cyclohexakis-(1-4)-(alpha-D-glucopyranose), ... | Authors: | Mikami, B, Hehre, E.J, Sato, M, Katsube, Y, Hirose, M, Morita, Y, Sacchettini, J.C. | Deposit date: | 1993-02-18 | Release date: | 1993-10-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The 2.0-A resolution structure of soybean beta-amylase complexed with alpha-cyclodextrin. Biochemistry, 32, 1993
|
|
4M9E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4m9e by Molmil](/molmil-images/mine/4m9e) | Structure of Klf4 zinc finger DNA binding domain in complex with methylated DNA | Descriptor: | ACETATE ION, DNA (5'-D(*GP*AP*GP*GP*(5CM)P*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*(5CM)P*GP*CP*CP*TP*C)-3'), ... | Authors: | Liu, Y, Olanrewaju, Y.O, Blumenthal, R.M, Zhang, X, Cheng, X. | Deposit date: | 2013-08-14 | Release date: | 2014-02-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.851 Å) | Cite: | Structural basis for Klf4 recognition of methylated DNA. Nucleic Acids Res., 42, 2014
|
|
4K2Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4k2y by Molmil](/molmil-images/mine/4k2y) | Crystal Structure of Human Chymase in Complex with Fragment Inhibitor 6-chloro-1,3-dihydro-2H-indol-2-one | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-chloro-1,3-dihydro-2H-indol-2-one, Chymase, ... | Authors: | Collins, B.K, Padyana, A.K. | Deposit date: | 2013-04-09 | Release date: | 2013-05-29 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Discovery of Potent, Selective Chymase Inhibitors via Fragment Linking Strategies. J.Med.Chem., 56, 2013
|
|
1WYC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1wyc by Molmil](/molmil-images/mine/1wyc) | Structure of 6-aminohexanoate-dimer hydrolase, DN mutant | Descriptor: | 6-aminohexanoate-dimer hydrolase | Authors: | Negoro, S, Ohki, T, Shibata, N, Mizuno, N, Wakitani, Y, Tsurukame, J, Matsumoto, K, Kawamoto, I, Takeo, M, Higuchi, Y. | Deposit date: | 2005-02-09 | Release date: | 2006-02-21 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Nylon-oligomer degrading enzyme/substrate complex: catalytic mechanism of 6-aminohexanoate-dimer hydrolase J.Mol.Biol., 370, 2007
|
|
6IG8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ig8 by Molmil](/molmil-images/mine/6ig8) | Crystal structure of CSF-1R kinase domain with a small molecular inhibitor, JTE-952 | Descriptor: | (3-{4-[(4-cyclopropylphenyl)methoxy]-3-methoxyphenyl}azetidin-1-yl)(4-{[(2S)-2,3-dihydroxypropoxy]methyl}pyridin-2-yl)methanone, GLYCEROL, MAGNESIUM ION, ... | Authors: | Doi, S, Adachi, T. | Deposit date: | 2018-09-25 | Release date: | 2019-08-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Discovery of a novel azetidine scaffold for colony stimulating factor-1 receptor (CSF-1R) Type II inhibitors by the use of docking models. Bioorg.Med.Chem.Lett., 29, 2019
|
|
1XYF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xyf by Molmil](/molmil-images/mine/1xyf) | ENDO-1,4-BETA-XYLANASE FROM STREPTOMYCES OLIVACEOVIRIDIS | Descriptor: | ENDO-1,4-BETA-XYLANASE | Authors: | Fujimoto, Z, Mizuno, H, Kuno, A, Kusakabe, I. | Deposit date: | 1999-05-11 | Release date: | 2000-05-10 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of Streptomyces olivaceoviridis E-86 beta-xylanase containing xylan-binding domain. J.Mol.Biol., 300, 2000
|
|
3S0N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3s0n by Molmil](/molmil-images/mine/3s0n) | Crystal Structure of Human Chymase with Benzimidazolone Inhibitor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-{3-[(4-methyl-1-benzothiophen-3-yl)methyl]-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl}butanoic acid, Chymase, ... | Authors: | Qian, K.C, Farrow, N.A, Padyana, A.K. | Deposit date: | 2011-05-13 | Release date: | 2011-07-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Benzimidazolone as potent chymase inhibitor: Modulation of reactive metabolite formation in the hydrophobic (P(1)) region. Bioorg.Med.Chem.Lett., 21, 2011
|
|
6L68
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6l68 by Molmil](/molmil-images/mine/6l68) | X-ray structure of human galectin-10 in complex with D-allose | Descriptor: | Galectin-10, beta-D-allopyranose | Authors: | Kamitori, S. | Deposit date: | 2019-10-28 | Release date: | 2020-03-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structures of human galectin-10/monosaccharide complexes demonstrate potential of monosaccharides as effectors in forming Charcot-Leyden crystals. Biochem.Biophys.Res.Commun., 2020
|
|
3WPN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3wpn by Molmil](/molmil-images/mine/3wpn) | |
7X4N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7x4n by Molmil](/molmil-images/mine/7x4n) | Crystal Structure of C. elegans kinesin-4 KLP-12 complexed with tubulin and DARPin | Descriptor: | DARPin, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Taguchi, S, Imasaki, T, Saijo-Hamano, Y, Sakai, N, Nitta, R. | Deposit date: | 2022-03-03 | Release date: | 2022-09-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.88 Å) | Cite: | Structural model of microtubule dynamics inhibition by kinesin-4 from the crystal structure of KLP-12 -tubulin complex. Elife, 11, 2022
|
|
7VU9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vu9 by Molmil](/molmil-images/mine/7vu9) | |
1RGN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1rgn by Molmil](/molmil-images/mine/1rgn) | Structure of the reaction centre from Rhodobacter sphaeroides carotenoidless strain R-26.1 reconstituted with spheroidene | Descriptor: | BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, FE (III) ION, ... | Authors: | Roszak, A.W, Frank, H.A, McKendrick, K, Mitchell, I.A, Cogdell, R.J, Isaacs, N.W. | Deposit date: | 2003-11-12 | Release date: | 2004-04-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Protein Regulation of Carotenoid Binding: Gatekeeper and Locking Amino Acid Residues in Reaction Centers of Rhodobacter sphaeroides STRUCTURE, 12, 2004
|
|
1B4U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1b4u by Molmil](/molmil-images/mine/1b4u) | PROTOCATECHUATE 4,5-DIOXYGENASE (LIGAB) IN COMPLEX WITH PROTOCATECHUATE (PCA) | Descriptor: | 3,4-DIHYDROXYBENZOIC ACID, FE (III) ION, PROTOCATECHUATE 4,5-DIOXYGENASE | Authors: | Sugimoto, K, Senda, T, Mitsui, Y. | Deposit date: | 1998-12-29 | Release date: | 1999-08-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of an aromatic ring opening dioxygenase LigAB, a protocatechuate 4,5-dioxygenase, under aerobic conditions. Structure Fold.Des., 7, 1999
|
|
7VOZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7voz by Molmil](/molmil-images/mine/7voz) | |
1BOU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1bou by Molmil](/molmil-images/mine/1bou) | THREE-DIMENSIONAL STRUCTURE OF LIGAB | Descriptor: | 4,5-DIOXYGENASE ALPHA CHAIN, 4,5-DIOXYGENASE BETA CHAIN, FE (III) ION | Authors: | Sugimoto, K, Senda, T, Fukuda, M, Mitsui, Y. | Deposit date: | 1998-08-06 | Release date: | 1999-05-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of an aromatic ring opening dioxygenase LigAB, a protocatechuate 4,5-dioxygenase, under aerobic conditions. Structure, 7, 1999
|
|
1F88
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1f88 by Molmil](/molmil-images/mine/1f88) | CRYSTAL STRUCTURE OF BOVINE RHODOPSIN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MERCURY (II) ION, RETINAL, ... | Authors: | Okada, T, Palczewski, K, Stenkamp, R.E, Miyano, M. | Deposit date: | 2000-06-29 | Release date: | 2000-08-04 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of rhodopsin: A G protein-coupled receptor. Science, 289, 2000
|
|
1X2A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1x2a by Molmil](/molmil-images/mine/1x2a) | Crystal Structure of e.coli AspAT complexed with N-phosphopyridoxyl-D-glutamic acid | Descriptor: | Aspartate aminotransferase, N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-D-GLUTAMIC ACID | Authors: | Goto, M. | Deposit date: | 2005-04-21 | Release date: | 2005-06-14 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Binding of C5-dicarboxylic substrate to aspartate aminotransferase: implications for the conformational change at the transaldimination step. Biochemistry, 44, 2005
|
|
3HAT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hat by Molmil](/molmil-images/mine/3hat) | ACTIVE SITE MIMETIC INHIBITION OF THROMBIN | Descriptor: | FPAM (FIBRINOPEPTIDE A MIMIC), Hirudin variant-2, Thrombin heavy chain, ... | Authors: | Tulinsky, A, Mathews, I.I. | Deposit date: | 1994-10-16 | Release date: | 1995-02-27 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Active-site mimetic inhibition of thrombin. Acta Crystallogr.,Sect.D, 51, 1995
|
|
1X28
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1x28 by Molmil](/molmil-images/mine/1x28) | Crystal Structure of e.coli AspAT complexed with N-phosphopyridoxyl-L-glutamic acid | Descriptor: | Aspartate aminotransferase, N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-L-glutamic acid | Authors: | Goto, M. | Deposit date: | 2005-04-21 | Release date: | 2005-06-14 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Binding of C5-dicarboxylic substrate to aspartate aminotransferase: implications for the conformational change at the transaldimination step. Biochemistry, 44, 2005
|
|