7X4N

Crystal Structure of C. elegans kinesin-4 KLP-12 complexed with tubulin and DARPin

Summary for 7X4N

Entry DOI	10.2210/pdb7x4n/pdb
Descriptor	Tubulin alpha-1A chain, Tubulin beta chain, DARPin, ... (8 entities in total)
Functional Keywords	kinesin-4, klp-12, kif21a, kif21b, microtubule, tubulin, axon, cfeom1, darpin, motor protein
Biological source	synthetic construct More
Total number of polymer chains	4
Total formula weight	158355.42
Authors	Taguchi, S.,Imasaki, T.,Saijo-Hamano, Y.,Sakai, N.,Nitta, R. (deposition date: 2022-03-03, release date: 2022-09-21, Last modification date: 2023-11-29)
Primary citation	Taguchi, S.,Nakano, J.,Imasaki, T.,Kita, T.,Saijo-Hamano, Y.,Sakai, N.,Shigematsu, H.,Okuma, H.,Shimizu, T.,Nitta, E.,Kikkawa, S.,Mizobuchi, S.,Niwa, S.,Nitta, R. Structural model of microtubule dynamics inhibition by kinesin-4 from the crystal structure of KLP-12 -tubulin complex. Elife, 11:-, 2022 Cited by PubMed: 36065637 DOI: 10.7554/eLife.77877 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.88 Å)

Structure validation