7X4N

Crystal Structure of C. elegans kinesin-4 KLP-12 complexed with tubulin and DARPin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Tubulin alpha-1A chain	polymer	451	50121.3	1	UniProt (P02550) Pfam (PF00091) Pfam (PF03953)	Sus scrofa (pig)	Alpha-tubulin 1,Tubulin alpha-1 chain
2	B (B)	Tubulin beta chain	polymer	445	49907.8	1	UniProt (P02554) Pfam (PF00091) Pfam (PF03953)	Sus scrofa (pig)	Beta-tubulin
3	C (C)	DARPin	polymer	159	16792.0	1		synthetic construct
4	D (E)	Kinesin-like protein	polymer	365	40013.2	1	UniProt (G5EGS3) Pfam (PF00225)	Caenorhabditis elegans
5	E (A)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	1	Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466)
6	F, I (A, E)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG) PubChem (888)
7	G (B)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537)
8	H (E)	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	1	Chemie (ANP)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	156834.2
Non-Polymers*	Number of molecules	5
	Total formula weight	1521.2
All*	Total formula weight	158355.4

*Water molecules are not included.