Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
7ZXU
DownloadVisualize
BU of 7zxu by Molmil
SARS-CoV-2 Omicron BA.4/5 RBD in complex with Beta-27 Fab and C1 nanobody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-27 heavy chain, Beta-27 light chain, ...
Authors:Huo, J, Zhou, D, Ren, J, Stuart, D.I.
Deposit date:2022-05-23
Release date:2022-06-29
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Antibody escape of SARS-CoV-2 Omicron BA.4 and BA.5 from vaccine and BA.1 serum.
Cell, 185, 2022
4O1S
DownloadVisualize
BU of 4o1s by Molmil
Crystal structure of TvoVMA intein
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SULFATE ION, ...
Authors:Aranko, A.S, Oeemig, J.S, Zhou, D, Kajander, T, Wlodawer, A, Iwai, H.
Deposit date:2013-12-16
Release date:2014-03-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7008 Å)
Cite:Structure-based engineering and comparison of novel split inteins for protein ligation.
Mol Biosyst, 10, 2014
4O1R
DownloadVisualize
BU of 4o1r by Molmil
Crystal structure of NpuDnaB intein
Descriptor: CHLORIDE ION, GLYCEROL, Replicative DNA helicase, ...
Authors:Aranko, A.S, Oeemig, J.S, Zhou, D, Kajander, T, Wlodawer, A, Iwai, H.
Deposit date:2013-12-16
Release date:2014-03-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure-based engineering and comparison of novel split inteins for protein ligation.
Mol Biosyst, 10, 2014
4PKM
DownloadVisualize
BU of 4pkm by Molmil
Crystal Structure of Bacillus thuringiensis Cry51Aa1 Protoxin at 1.65 Angstroms Resolution
Descriptor: Cry51Aa1, GLYCEROL, GLYCINE, ...
Authors:Xu, C, Chinte, U, Chen, L, Yao, Q, Zhou, D, Meng, Y, Li, L, Rose, J, Bi, L.J, Yu, Z, Sun, M, Wang, B.C.
Deposit date:2014-05-15
Release date:2015-06-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of Cry51Aa1: A potential novel insecticidal aerolysin-type beta-pore-forming toxin from Bacillus thuringiensis.
Biochem.Biophys.Res.Commun., 462, 2015
8CIN
DownloadVisualize
BU of 8cin by Molmil
BA.4/5-5 FAB IN COMPLEX WITH SARS-COV-2 BA.4 SPIKE GLYCOPROTEIN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BA.4/5-5 fab HEAVY CHAIN, ...
Authors:Duyvesteyn, H.M.E, Ren, J, Stuart, D.I, Fry, E.E.
Deposit date:2023-02-10
Release date:2024-02-21
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:The SARS-CoV-2 neutralizing antibody response to SD1 and its evasion by BA.2.86.
Nat Commun, 15, 2024
8R1C
DownloadVisualize
BU of 8r1c by Molmil
SD1-2 Fab in complex with SARS-CoV-2 BA.2.12.1 Spike Glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, SD1-2 fab heavy chain, SD1-2 fab light chain, ...
Authors:Duyvesteyn, H.M.E, Ren, J, Stuart, D.I.
Deposit date:2023-11-01
Release date:2024-03-13
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:The SARS-CoV-2 neutralizing antibody response to SD1 and its evasion by BA.2.86.
Nat Commun, 15, 2024
8R1D
DownloadVisualize
BU of 8r1d by Molmil
SD1-3 Fab in complex with SARS-CoV-2 BA.2.12.1 Spike Glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, SD1-3 Fab Heavy Chain, SD1-3 Fab Light Chain, ...
Authors:Duyvesteyn, H.M.E, Ren, J, Stuart, D.I.
Deposit date:2023-11-01
Release date:2024-03-13
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (2.37 Å)
Cite:The SARS-CoV-2 neutralizing antibody response to SD1 and its evasion by BA.2.86.
Nat Commun, 15, 2024
5Z1G
DownloadVisualize
BU of 5z1g by Molmil
Structure of the Brx1 and Ebp2 complex
Descriptor: Ribosome biogenesis protein BRX1, SULFATE ION, rRNA-processing protein EBP2
Authors:Zheng, S, Ye, K.
Deposit date:2017-12-26
Release date:2018-04-11
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.294 Å)
Cite:Cryo-EM structure of an early precursor of large ribosomal subunit reveals a half-assembled intermediate
Protein Cell, 10, 2019
8HJE
DownloadVisualize
BU of 8hje by Molmil
Vismodegib binds to the catalytical domain of human Ubiquitin-Specific Protease 28
Descriptor: 2-chloranyl-~{N}-(4-chloranyl-3-pyridin-2-yl-phenyl)-4-methylsulfonyl-benzamide, Ubiquitin carboxyl-terminal hydrolase 28
Authors:Shi, L, Wang, H, Xu, Z, Xiong, B, Zhang, N.
Deposit date:2022-11-23
Release date:2023-05-03
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure-based discovery of potent USP28 inhibitors derived from Vismodegib.
Eur.J.Med.Chem., 254, 2023
4WBQ
DownloadVisualize
BU of 4wbq by Molmil
Crystal structure of the exonuclease domain of QIP (QDE-2 interacting protein) solved by native-SAD phasing.
Descriptor: CALCIUM ION, QDE-2-interacting protein
Authors:Boland, A, Weinert, T, Weichenrieder, O, Wang, M.
Deposit date:2014-09-03
Release date:2014-12-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.693 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
6J6M
DownloadVisualize
BU of 6j6m by Molmil
Co-crystal structure of BTK kinase domain with Zanubrutinib
Descriptor: (7S)-2-(4-phenoxyphenyl)-7-(1-propanoylpiperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, IMIDAZOLE, Tyrosine-protein kinase BTK
Authors:Zhou, X, Hong, Y.
Deposit date:2019-01-15
Release date:2019-10-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Discovery of Zanubrutinib (BGB-3111), a Novel, Potent, and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase.
J.Med.Chem., 62, 2019
3IK3
DownloadVisualize
BU of 3ik3 by Molmil
AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance
Descriptor: 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide, Proto-oncogene tyrosine-protein kinase ABL1
Authors:Zhou, T.
Deposit date:2009-08-05
Release date:2009-11-03
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance.
Cancer Cell, 16, 2009
4WAB
DownloadVisualize
BU of 4wab by Molmil
Crystal structure of mPGES1 solved by native-SAD phasing
Descriptor: 2-[[2,6-bis(chloranyl)-3-[(2,2-dimethylpropanoylamino)methyl]phenyl]amino]-1-methyl-6-(2-methyl-2-oxidanyl-propoxy)-N-[2,2,2-tris(fluoranyl)ethyl]benzimidazole-5-carboxamide, GLUTATHIONE, Prostaglandin E synthase,Leukotriene C4 synthase
Authors:Weinert, T, Li, D, Howe, N, Caffrey, M, Wang, M.
Deposit date:2014-08-29
Release date:2014-12-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.704 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
4WBX
DownloadVisualize
BU of 4wbx by Molmil
Conserved hypothetical protein PF1771 from Pyrococcus furiosus solved by sulfur SAD using Swiss Light Source data
Descriptor: 2-keto acid:ferredoxin oxidoreductase subunit alpha
Authors:Weinert, T, Waltersperger, S, Olieric, V, Panepucci, E, Chen, L, Rose, J.P, Wang, M, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2014-09-04
Release date:2014-12-10
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
4WAU
DownloadVisualize
BU of 4wau by Molmil
Crystal structure of CENP-M solved by native-SAD phasing
Descriptor: Centromere protein M
Authors:Weinert, T, Basilico, F, Cecatiello, V, Pasqualato, S, Wang, M.
Deposit date:2014-09-01
Release date:2014-12-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
2QYU
DownloadVisualize
BU of 2qyu by Molmil
Crystal structure of Salmonella effector protein SopA
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHOSPHATE ION, Secreted effector protein
Authors:Diao, J, Chen, J.
Deposit date:2007-08-15
Release date:2007-12-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of SopA, a Salmonella effector protein mimicking a eukaryotic ubiquitin ligase.
Nat.Struct.Mol.Biol., 15, 2008
2QZA
DownloadVisualize
BU of 2qza by Molmil
Crystal structure of Salmonella effector protein SopA
Descriptor: Secreted effector protein
Authors:Diao, J, Chen, J.
Deposit date:2007-08-16
Release date:2007-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of SopA, a Salmonella effector protein mimicking a eukaryotic ubiquitin ligase.
Nat.Struct.Mol.Biol., 15, 2008
6E5G
DownloadVisualize
BU of 6e5g by Molmil
Crystal structure of human TEAD2-Yap binding domain covalently bound to an allosteric regulator
Descriptor: 1-(2-{[3-(trifluoromethyl)phenyl]amino}phenyl)ethan-1-one, Transcriptional enhancer factor TEF-4
Authors:Bum-Erdene, K, Gonzalez-Gutierrez, G, Meroueh, S.O.
Deposit date:2018-07-20
Release date:2019-01-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Small-Molecule Covalent Modification of Conserved Cysteine Leads to Allosteric Inhibition of the TEAD⋅Yap Protein-Protein Interaction.
Cell Chem Biol, 26, 2019
8BCZ
DownloadVisualize
BU of 8bcz by Molmil
SARS-CoV-2 Delta-RBD complexed with Fabs BA.2-36, BA.2-23, EY6A and COVOX-45
Descriptor: BA.2-23 heavy chain, BA.2-23 light chain, BA.2-36 heavy chain, ...
Authors:Duyvesteyn, H.M.E, Ren, J, Stuart, D.I.
Deposit date:2022-10-17
Release date:2023-03-22
Last modified:2023-04-12
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Rapid escape of new SARS-CoV-2 Omicron variants from BA.2-directed antibody responses.
Cell Rep, 42, 2023
6ZH9
DownloadVisualize
BU of 6zh9 by Molmil
Ternary complex CR3022 H11-H4 and RBD (SARS-CoV-2)
Descriptor: CR3022 Light chain, CR3022 heavy, Nanobody H11-H4, ...
Authors:Naismith, J.H, Mikolajek, H, Le Bas, A.
Deposit date:2020-06-21
Release date:2020-09-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2.
Nat.Struct.Mol.Biol., 27, 2020
7Q6E
DownloadVisualize
BU of 7q6e by Molmil
Beta049 fab in complex with SARS-CoV2 beta-Spike glycoprotein, The Beta mAb response underscores the antigenic distance to other SARS-CoV-2 variants
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-49 heavy chain, ...
Authors:Duyvesteyn, H.M.E, Ren, J, Stuart, D.I.
Deposit date:2021-11-07
Release date:2021-12-15
Last modified:2022-01-26
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants.
Cell Host Microbe, 30, 2022
7Q9F
DownloadVisualize
BU of 7q9f by Molmil
Beta-50 fab in complex with SARS-CoV-2 beta-Spike glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Duyvesteyn, H.M.E, Ren, J, Stuart, D.I.
Deposit date:2021-11-12
Release date:2021-12-15
Last modified:2022-01-26
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants.
Cell Host Microbe, 30, 2022
7Q9J
DownloadVisualize
BU of 7q9j by Molmil
Beta-26 fab in complex with SARS-CoV-2 beta-Spike glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-26 heavy chain, ...
Authors:Duyvesteyn, H.M.E, Ren, J, Stuart, D.I.
Deposit date:2021-11-12
Release date:2021-12-15
Last modified:2022-01-26
Method:ELECTRON MICROSCOPY (4 Å)
Cite:The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants.
Cell Host Microbe, 30, 2022
7Q9G
DownloadVisualize
BU of 7q9g by Molmil
COVOX-222 fab in complex with SARS-CoV-2 beta-Spike glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COVOX-222 heavy chain, ...
Authors:Duyvesteyn, H.M.E, Ren, J, Stuart, D.I.
Deposit date:2021-11-12
Release date:2021-12-15
Last modified:2022-01-26
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants.
Cell Host Microbe, 30, 2022
7Q9I
DownloadVisualize
BU of 7q9i by Molmil
Beta-43 fab in complex with SARS-CoV-2 beta-Spike glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-43 heavy chain, ...
Authors:Duyvesteyn, H.M.E, Ren, J, Stuart, D.I.
Deposit date:2021-11-12
Release date:2021-12-15
Last modified:2022-01-26
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants.
Cell Host Microbe, 30, 2022

221716

数据于2024-06-26公开中

PDB statisticsPDBj update infoContact PDBjnumon