8DAO
| Crystal structure of SARS-CoV-2 spike stem fusion peptide in complex with neutralizing antibody COV44-79 | Descriptor: | COV44-79 heavy chain constant domain, COV44-79 heavy chain variable domain, COV44-79 light chain constant domain, ... | Authors: | Lin, T.H, Lee, C.C.D, Yuan, M, Wilson, I.A. | Deposit date: | 2022-06-13 | Release date: | 2022-07-27 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Broadly neutralizing antibodies target the coronavirus fusion peptide. Science, 377, 2022
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8D36
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8DTT
| Crystal structure of SARS-CoV-2 spike stem helix peptide in complex with neutralizing antibody COV93-03 | Descriptor: | COV93-03 heavy chain, COV93-03 light chain, Spike protein S2' stem helix peptide | Authors: | Lee, C.C.D, Lin, T.H, Wilson, I.A. | Deposit date: | 2022-07-26 | Release date: | 2022-11-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses. Cell Host Microbe, 31, 2023
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8DTX
| Crystal structure of SARS-CoV-2 spike stem helix peptide in complex with neutralizing antibody COV89-22 | Descriptor: | COV89-22 heavy chain, COV89-22 light chain, Spike protein S2' stem helix peptide | Authors: | Lin, T.H, Lee, C.C.D, Wilson, I.A. | Deposit date: | 2022-07-26 | Release date: | 2022-11-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses. Cell Host Microbe, 31, 2023
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8DTR
| Crystal structure of SARS-CoV-2 spike stem helix peptide in complex with neutralizing antibody COV30-14 | Descriptor: | COV30-14 heavy chain, COV30-14 light chain, Spike protein S2' stem helix peptide | Authors: | Lee, C.C.D, Lin, T.H, Wilson, I.A. | Deposit date: | 2022-07-26 | Release date: | 2022-11-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses. Cell Host Microbe, 31, 2023
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6NV1
| Structure of drug-resistant V27A mutant of the influenza M2 proton channel bound to spiroadamantyl amine inhibitor | Descriptor: | (1r,1'S,3'S,5'S,7'S)-spiro[cyclohexane-1,2'-tricyclo[3.3.1.1~3,7~]decan]-4-amine, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, ... | Authors: | Thomaston, J.L, Liu, L, DeGrado, W.F. | Deposit date: | 2019-02-04 | Release date: | 2020-01-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | X-ray Crystal Structures of the Influenza M2 Proton Channel Drug-Resistant V27A Mutant Bound to a Spiro-Adamantyl Amine Inhibitor Reveal the Mechanism of Adamantane Resistance. Biochemistry, 59, 2020
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5A9W
| Structure of GDPCP BipA | Descriptor: | GTP-BINDING PROTEIN, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | Authors: | Kumar, V, Chen, Y, Ero, R, Li, Z, Gao, Y. | Deposit date: | 2015-07-23 | Release date: | 2015-08-26 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome. Proc.Natl.Acad.Sci.USA, 112, 2015
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5A9V
| Structure of apo BipA | Descriptor: | GTP-BINDING PROTEIN | Authors: | Kumar, V, Chen, Y, Ero, R, Li, Z, Gao, Y. | Deposit date: | 2015-07-23 | Release date: | 2015-09-02 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.31 Å) | Cite: | Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome. Proc.Natl.Acad.Sci.USA, 112, 2015
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5A9Y
| Structure of ppGpp BipA | Descriptor: | GTP-BINDING PROTEIN, GUANOSINE-5',3'-TETRAPHOSPHATE | Authors: | Kumar, V, Chen, Y, Ero, R, Li, Z, Gao, Y.-G. | Deposit date: | 2015-07-23 | Release date: | 2015-08-26 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome. Proc.Natl.Acad.Sci.USA, 112, 2015
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5A9X
| Structure of GDP bound BipA | Descriptor: | GTP-BINDING PROTEIN, GUANOSINE-5'-DIPHOSPHATE | Authors: | Kumar, V, Chen, Y, Ero, R, Li, Z, Gao, Y.-G. | Deposit date: | 2015-07-23 | Release date: | 2015-08-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome. Proc.Natl.Acad.Sci.USA, 112, 2015
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7KHF
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7KFK
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6IUY
| Structure of DsGPDH of Dunaliella salina | Descriptor: | 1,3-DIHYDROXYACETONEPHOSPHATE, GLYCEROL, Glycerol-3-phosphate dehydrogenase [NAD(+)], ... | Authors: | He, Q, Toh, J.D, Ero, R, Qiao, Z, Kumar, V, Gao, Y.G. | Deposit date: | 2018-12-01 | Release date: | 2019-12-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The unusual di-domain structure of Dunaliella salina glycerol-3-phosphate dehydrogenase enables direct conversion of dihydroxyacetone phosphate to glycerol. Plant J., 102, 2020
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4PW2
| Crystal structure of D-glucuronyl C5 epimerase | Descriptor: | CITRIC ACID, D-glucuronyl C5 epimerase B | Authors: | Ke, J, Qin, Y, Gu, X, Brunzelle, J.S, Xu, H.E, Ding, K. | Deposit date: | 2014-03-18 | Release date: | 2015-01-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and Functional Study of d-Glucuronyl C5-epimerase. J.Biol.Chem., 290, 2015
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3LQ8
| Structure of the kinase domain of c-Met bound to XL880 (GSK1363089) | Descriptor: | Hepatocyte growth factor receptor, N-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Authors: | Lougheed, J.C, Stout, T.J. | Deposit date: | 2010-02-08 | Release date: | 2010-05-19 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Inhibition of tumor cell growth, invasion, and metastasis by EXEL-2880 (XL880, GSK1363089), a novel inhibitor of HGF and VEGF receptor tyrosine kinases. Cancer Res., 69, 2009
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2OJU
| X-ray structure of complex of human cyclophilin J with cyclosporin A | Descriptor: | CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 3 | Authors: | Xia, Z, Huang, L. | Deposit date: | 2007-01-14 | Release date: | 2008-01-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Targeting Cyclophilin J, a Novel Peptidyl-Prolyl Isomerase, Can Induce Cellular G1/S Arrest and Repress the Growth of Hepatocellular Carcinoma To be Published
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2OK3
| X-ray structure of human cyclophilin J at 2.0 angstrom | Descriptor: | NICKEL (II) ION, Peptidyl-prolyl cis-trans isomerase-like 3 | Authors: | Xia, Z. | Deposit date: | 2007-01-15 | Release date: | 2008-01-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Targeting Cyclophilin J, a novel peptidyl-prolyl isomerase, can induce cellular G1/S arrest and repress the growth of Hepatocellular carcinoma To be Published
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6V4N
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6V4O
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5EPO
| The three-dimensional structure of Clostridium absonum 7alpha-hydroxysteroid dehydrogenase | Descriptor: | 7-alpha-hydroxysteroid deydrogenase, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Lou, D, Wang, B, Wang, F. | Deposit date: | 2015-11-12 | Release date: | 2016-03-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The three-dimensional structure of Clostridium absonum 7 alpha-hydroxysteroid dehydrogenase: new insights into the conserved arginines for NADP(H) recognition Sci Rep, 6, 2016
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3FFV
| Crystal Structure Analysis of Syd | Descriptor: | Protein syd | Authors: | Maurus, R, Brayer, G.D. | Deposit date: | 2008-12-04 | Release date: | 2009-01-27 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure, Binding, and Activity of Syd, a SecY-interacting Protein J.Biol.Chem., 284, 2009
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5ZF2
| Crystal structure of Trxlp from Edwardsiella tarda EIB202 | Descriptor: | SULFATE ION, Thioredoxin (H-type,TRX-H) | Authors: | Yang, C, Quan, S. | Deposit date: | 2018-03-02 | Release date: | 2019-03-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | The Edwardsiella piscicida thioredoxin-like protein inhibits ASK1-MAPKs signaling cascades to promote pathogenesis during infection. Plos Pathog., 15, 2019
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6K2U
| Crystal structure of Thr66 ADP-ribosylated ubiquitin | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, MAGNESIUM ION, Polyubiquitin-C, ... | Authors: | Wang, X, Zhou, Y, Zhu, Y. | Deposit date: | 2019-05-15 | Release date: | 2020-03-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.554 Å) | Cite: | Threonine ADP-Ribosylation of Ubiquitin by a Bacterial Effector Family Blocks Host Ubiquitination. Mol.Cell, 78, 2020
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3DVG
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3DVN
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