3A1A

Crystal Structure of the DNMT3A ADD domain

Summary for 3A1A

Related3A1B
DescriptorDNA (cytosine-5)-methyltransferase 3A, ZINC ION, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywordszinc-finger, alternative promoter usage, dna-binding, metal-binding, methyltransferase, nucleus, phosphoprotein, s-adenosyl-l-methionine, transferase
Biological sourceHomo sapiens (Human)
Cellular locationNucleus Q9Y6K1
Total number of polymer chains1
Total molecular weight16570
Authors
Otani, J.,Arita, K.,Ariyoshi, M.,Shirakawa, M. (deposition date: 2009-03-28, release date: 2009-11-10, Last modification date: 2011-07-13)
Primary citation
Otani, J.,Nankumo, T.,Arita, K.,Inamoto, S.,Ariyoshi, M.,Shirakawa, M.
Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain
Embo Rep., 10:1235-1241, 2009
PubMed: 19834512 (PDB entries with the same primary citation)
DOI: 10.1038/embor.2009.218
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.3 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliers 0.24340 3.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
170172
PDB entries from 2020-10-21