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3VXX

Crystal structure of methyl CpG binding domain of MBD4 in complex with the 5mCG/5mCG sequence

Summary for 3VXX
Entry DOI10.2210/pdb3vxx/pdb
Related3VXV 3VYB 3VYQ
DescriptorMethyl-CpG-binding domain protein 4, DNA (5'-D(*GP*TP*CP*AP*CP*TP*AP*CP*(5CM)P*GP*GP*AP*CP*A)-3'), DNA (5'-D(*GP*TP*CP*(5CM)P*GP*GP*TP*AP*GP*TP*GP*AP*CP*T)-3'), ... (6 entities in total)
Functional Keywordsmethyl cpg binding domain, protein-dna complex, versatile base recognition, hydrolase-dna complex, hydrolase/dna
Biological sourceMus musculus (mouse)
More
Cellular locationNucleus: Q9Z2D7
Total number of polymer chains3
Total formula weight16959.19
Authors
Otani, J.,Arita, K.,Kato, T.,Kinoshita, M.,Ariyoshi, M.,Shirakawa, M. (deposition date: 2012-09-21, release date: 2013-01-16, Last modification date: 2023-11-08)
Primary citationOtani, J.,Arita, K.,Kato, T.,Kinoshita, M.,Kimura, H.,Suetake, I.,Tajima, S.,Ariyoshi, M.,Shirakawa, M.
Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4
J.Biol.Chem., 288:6351-6362, 2013
Cited by
PubMed: 23316048
DOI: 10.1074/jbc.M112.431098
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.204 Å)
Structure validation

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