6TL5

Three dimensional structure of human carbonic anhydrase IX in complex with sulfonamide

Summary for 6TL5

Entry DOI	10.2210/pdb6tl5/pdb
Descriptor	Carbonic anhydrase 9, 3,5-diphenylbenzenesulfonamide, ZINC ION, ... (4 entities in total)
Functional Keywords	lyase
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	114246.01
Authors	Leitans, J.,Tars, K. (deposition date: 2019-12-01, release date: 2020-12-16, Last modification date: 2024-01-24)
Primary citation	Dudutiene, V.,Zubriene, A.,Kairys, V.,Smirnov, A.,Smirnoviene, J.,Leitans, J.,Kazaks, A.,Tars, K.,Manakova, L.,Grazulis, S.,Matulis, D. Isoform-Selective Enzyme Inhibitors by Exploring Pocket Size According to the Lock-and-Key Principle. Biophys.J., 119:1513-1524, 2020 Cited by PubMed: 32971003 DOI: 10.1016/j.bpj.2020.08.037 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.21 Å)

Structure validation