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3CFC
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BU of 3cfc by Molmil
High-resolution structure of blue fluorescent antibody EP2-19G2
Descriptor: BLUE FLUORESCENT ANTIBODY EP2-19G2-IGG2B HEAVY CHAIN, BLUE FLUORESCENT ANTIBODY EP2-19G2-KAPPA LIGHT CHAIN, GLYCEROL
Authors:Debler, E.W, Wilson, I.A.
Deposit date:2008-03-03
Release date:2008-03-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex.
Science, 319, 2008
3CFB
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BU of 3cfb by Molmil
High-resolution structure of blue fluorescent antibody EP2-19G2 in complex with stilbene hapten at 100K
Descriptor: 4-(4-STYRYL-PHENYLCARBAMOYL)-BUTYRIC ACID, BLUE FLUORESCENT ANTIBODY EP2-19G2-IGG2B HEAVY CHAIN, BLUE FLUORESCENT ANTIBODY EP2-19G2-KAPPA LIGHT CHAIN, ...
Authors:Debler, E.W, Wilson, I.A.
Deposit date:2008-03-03
Release date:2008-03-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex.
Science, 319, 2008
3CN0
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BU of 3cn0 by Molmil
Human transthyretin (TTR) in complex with 3,5-Dimethyl-4-hydroxystilbene
Descriptor: 2,6-dimethyl-4-[(E)-2-phenylethenyl]phenol, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2008-03-24
Release date:2008-10-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Toward optimization of the linker substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies.
J.Med.Chem., 51, 2008
3CN1
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BU of 3cn1 by Molmil
Human transthyretin (TTR) in complex with 3,5-Dibromo-4-hydroxystilbene
Descriptor: 2,6-dibromo-4-[(E)-2-phenylethenyl]phenol, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2008-03-24
Release date:2008-10-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Toward optimization of the linker substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies.
J.Med.Chem., 51, 2008
2G2R
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BU of 2g2r by Molmil
Green-fluorescent antibody 11G10 in complex with its hapten (nitro-stilbene derivative)
Descriptor: Green-fluorescent antibody (11G10)-heavy chain, Green-fluorescent antibody (11G10)-light chain, N-(TRANS-4'-NITRO-4-STILBENYL)-N-METHYL-5-AMINO-PENTANOIC ACID, ...
Authors:Debler, E.W, Wilson, I.A.
Deposit date:2006-02-16
Release date:2006-12-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The Effects of Antibodies on Stilbene Excited-State Energetics.
Angew.Chem.Int.Ed.Engl., 45, 2006
3LZF
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BU of 3lzf by Molmil
Crystal Structure of Fab 2D1 in Complex with the 1918 Influenza Virus Hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2D1 Fab, ...
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2010-03-01
Release date:2010-04-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus.
Science, 328, 2010
3MJ9
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BU of 3mj9 by Molmil
Crystal structure of JAML in complex with the stimulatory antibody HL4E10
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Junctional adhesion molecule-like, STIMULATORY HAMSTER ANTIBODY HL4E10 FAB HEAVY CHAIN, ...
Authors:Verdino, P, Wilson, I.A.
Deposit date:2010-04-12
Release date:2011-02-23
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Molecular insights into gamma delta T cell costimulation by an anti-JAML antibody.
Structure, 19, 2011
3LZG
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BU of 3lzg by Molmil
Crystal structure of a 2009 H1N1 influenza virus hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Xu, R, Wilson, I.A.
Deposit date:2010-03-01
Release date:2010-04-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus.
Science, 328, 2010
3MJ8
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BU of 3mj8 by Molmil
Crystal structure of HL4E10 Fab, a hamster Ab stimulatory for gammadelta T cells
Descriptor: STIMULATORY HAMSTER ANTIBODY HL4E10 FAB HEAVY CHAIN, STIMULATORY HAMSTER ANTIBODY HL4E10 FAB LIGHT CHAIN
Authors:Verdino, P, Wilson, I.A.
Deposit date:2010-04-12
Release date:2011-04-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:cDNA sequence and Fab crystal structure of HL4E10, a hamster IgG lambda light chain antibody stimulatory for gammadelta T cells.
Plos One, 6, 2011
3MBE
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BU of 3mbe by Molmil
TCR 21.30 in complex with MHC class II I-Ag7HEL(11-27)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MHC CLASS II H2-IAg7 ALPHA CHAIN, ...
Authors:Corper, A.L, Yoshida, K, Teyton, L, Wilson, I.A.
Deposit date:2010-03-25
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.886 Å)
Cite:The diabetogenic mouse MHC class II molecule I-Ag7 is endowed with a switch that modulates TCR affinity.
J.Clin.Invest., 120, 2010
4GMT
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BU of 4gmt by Molmil
Crystal structure of heterosubtypic Fab S139/1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab S139/1 heavy chain, ...
Authors:Lee, P.S, Ekiert, D.C, Wilson, I.A.
Deposit date:2012-08-16
Release date:2012-10-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Heterosubtypic antibody recognition of the influenza virus hemagglutinin receptor binding site enhanced by avidity.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GDJ
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BU of 4gdj by Molmil
A subtype N10 neuraminidase-like protein of A/little yellow-shouldered bat/Guatemala/060/2010
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuraminidase, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2012-07-31
Release date:2012-09-26
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of two subtype N10 neuraminidase-like proteins from bat influenza A viruses reveal a diverged putative active site.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GHA
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BU of 4gha by Molmil
Crystal structure of Marburg virus VP35 RNA binding domain bound to 12-bp dsRNA
Descriptor: Polymerase cofactor VP35, RNA (5'-R(*CP*UP*AP*GP*AP*CP*GP*UP*CP*UP*AP*G)-3')
Authors:Bale, S, Jean-Philippe, J, Bornholdt, Z.A, Kimberlin, C.K, Halfmann, P, Zandonatti, M.A, Kunert, J, Kroon, G.J.A, Kawaoka, Y, MacRae, I.J, Wilson, I.A, Saphire, E.O.
Deposit date:2012-08-07
Release date:2012-08-22
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Marburg Virus VP35 Can Both Fully Coat the Backbone and Cap the Ends of dsRNA for Interferon Antagonism.
Plos Pathog., 8, 2012
4GH9
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BU of 4gh9 by Molmil
Crystal structure of Marburg virus VP35 RNA binding domain
Descriptor: ACETATE ION, Polymerase cofactor VP35
Authors:Bale, S, Jean-Philippe, J, Bornholdt, Z.A, Kimberlin, C.K, Halfmann, P, Zandonatti, M.A, Kunert, J, Kroon, G.J.A, Kawaoka, Y, MacRae, I.J, Wilson, I.A, Saphire, E.O.
Deposit date:2012-08-07
Release date:2012-08-15
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Marburg Virus VP35 Can Both Fully Coat the Backbone and Cap the Ends of dsRNA for Interferon Antagonism.
Plos Pathog., 8, 2012
4GXX
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BU of 4gxx by Molmil
Crystal structure of the "avianized" 1918 influenza virus hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ...
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2012-09-04
Release date:2012-12-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Influenza Human Monoclonal Antibody 1F1 Interacts with Three Major Antigenic Sites and Residues Mediating Human Receptor Specificity in H1N1 Viruses.
Plos Pathog., 8, 2012
4GZO
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BU of 4gzo by Molmil
N2 neuraminidase of A/Tanzania/205/2010 H3N2 in complex with hepes
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2012-09-06
Release date:2012-10-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors.
J.Virol., 86, 2012
4GZX
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BU of 4gzx by Molmil
N2 neuraminidase D151G mutant of A/Tanzania/205/2010 H3N2 in complex with human sialic acid receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2012-09-06
Release date:2012-10-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors.
J.Virol., 86, 2012
4GZS
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BU of 4gzs by Molmil
N2 neuraminidase D151G mutant of a/Tanzania/205/2010 H3N2 in complex with hepes
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2012-09-06
Release date:2012-10-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors.
J.Virol., 86, 2012
5VTV
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BU of 5vtv by Molmil
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin G225M/L226T/S228A mutant in complex with 3'-SLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-05-18
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin.
Cell Host Microbe, 21, 2017
5VTQ
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BU of 5vtq by Molmil
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin G225L/L226S mutant in complex with 3'-SLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-05-17
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin.
Cell Host Microbe, 21, 2017
5VTY
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BU of 5vty by Molmil
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin G225Q/L226A mutant in complex with 3'-SLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-05-18
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin.
Cell Host Microbe, 21, 2017
5VTX
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BU of 5vtx by Molmil
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin G225M/L226T/S228A mutant apo form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-05-18
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin.
Cell Host Microbe, 21, 2017
5VTU
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BU of 5vtu by Molmil
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin G225L/L226S mutant apo form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-05-18
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin.
Cell Host Microbe, 21, 2017
5WDU
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BU of 5wdu by Molmil
HIV-1 Env BG505 SOSIP.664 H72C-H564C trimer in complex with bNAbs PGT122 Fab, 35O22 Fab and NIH45-46 scFv
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:Julien, J.-P, Torrents de la Pena, A, Sanders, R.W, Wilson, I.A.
Deposit date:2017-07-06
Release date:2018-04-04
Last modified:2022-11-30
Method:X-RAY DIFFRACTION (7 Å)
Cite:Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization.
Cell Rep, 20, 2017
7JN5
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BU of 7jn5 by Molmil
Crystal structure of SARS-CoV receptor binding domain in complex with human antibody CR3022
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR3022 heavy chain, ...
Authors:Wu, N.C, Yuan, M, Zhu, X, Wilson, I.A.
Deposit date:2020-08-03
Release date:2020-10-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.705 Å)
Cite:A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody.
Plos Pathog., 16, 2020

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数据于2024-07-17公开中

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