4GZS

N2 neuraminidase D151G mutant of a/Tanzania/205/2010 H3N2 in complex with hepes

Summary for 4GZS

Entry DOI	10.2210/pdb4gzs/pdb
Related	4GZO 4GZP 4GZQ 4GZT 4GZW 4GZX
Descriptor	Neuraminidase, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	beta-propella, influenza virus, neuraminidase, hemagglutinin, hemadsorption, viral infection, viral protein
Biological source	Influenza A virus
Total number of polymer chains	4
Total formula weight	181037.07
Authors	Zhu, X.,Wilson, I.A. (deposition date: 2012-09-06, release date: 2012-10-17, Last modification date: 2023-09-13)
Primary citation	Zhu, X.,McBride, R.,Nycholat, C.M.,Yu, W.,Paulson, J.C.,Wilson, I.A. Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors. J.Virol., 86:13371-13383, 2012 Cited by PubMed: 23015718 DOI: 10.1128/JVI.01426-12 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation